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- W187054304 abstract "Nowadays, the development of pharmaceutical neuroenhancers attracts considerable attention due to their applicability and controversial implications within human society. Modafinil is one such neurorenhancer that has gained notoriety due to its widespread use in military and college environments. Several studies in the field of cognitive neuroscience, psychophysics and pharmacology have reported on the human brain differential processing under the influence of modafinil. Unfortunately, the underlying mechanisms by which modafinil modulates excitatory and inhibitory neural populations on cortical and subcortical neural networks as well as its positive or negative effects are not well understood. To cope with this, we propose a biologically-inspired, large-scale computational model for studying modafinil effects on electroencephalographic neural correlates of attention. Numerical simulations are performed and reconciled with recent experimental findings on the influence of modafinil on the locus coeruleus (LC) and the corticothalamic pathways. It is concluded that neural computational models represent a promising approach to gain insight into the neurodynamics of cognitive neuroenhancers." @default.
- W187054304 created "2016-06-24" @default.
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- W187054304 date "2013-01-01" @default.
- W187054304 modified "2023-09-24" @default.
- W187054304 title "Modeling the Effects of Modafinil on Selective Attention Electroencephalographic Neural Correlates" @default.
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- W187054304 doi "https://doi.org/10.1007/978-94-007-6253-4_5" @default.
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