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• W1870794863 abstract "Surface morphology of calcium alginate hydrogel microspheres (CAHM) with ultrahigh water content has been found to affect the interaction with proteins and cells in vivo. In this study, an optical interferometer is developed to firstly characterize spherical surface morphology of CAHM in wet and in situ under normal pressure and temperature. CAHM shows smoother surface with significant lower roughness than flat alginate membrane, which also contribute to significantly different surface morphology between spherical microcapsules and flat membrane after coating with chitosan. These results help to update the previous knowledge that flat surface can be used to simulate spherical surface for understanding hydrogel behavior to protein adsorption. Meanwhile, CAHM is characterized by SEM techniques with drying process at varying degrees, which demonstrates deviated surface morphology to the original wet surface. Therefore, the optical interferometer is proved a useful tool to acquire the authentic and accurate surface information of spherical hydrogels at applied wet state." @default.
• W1870794863 created "2016-06-24" @default.
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• W1870794863 date "2015-11-01" @default.
• W1870794863 modified "2023-09-26" @default.
• W1870794863 title "Investigation of spherical hydrogel surface with optical interferometer" @default.
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• W1870794863 doi "https://doi.org/10.1016/j.colsurfa.2015.08.028" @default.
• W1870794863 hasPublicationYear "2015" @default.
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