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• W187320833 abstract "Many Gram-negative pathogens evade the host's immune response by utilizing a specialized protein secretion machinery, known as type III secretion system (TTSS). Virulence factors such as the Yersinia outer protein E (YopE) are delivered directly into the cytosol of target cells in a TTSS-dependent fashion. This unique translocation mechanism can be used by attenuated Salmonella carrier vaccines for the delivery of heterologous antigens fused to YopE into the MHC class I-restricted antigen processing pathway. In orally immunized mice, this novel vaccination strategy results in the induction of pronounced peptide-specific cytotoxic CD8 T cell responses." @default.
• W187320833 created "2016-06-24" @default.
• W187320833 creator A5039095660 @default.
• W187320833 date "2006-03-09" @default.
• W187320833 modified "2023-09-24" @default.
• W187320833 title "Yersinia Outer Protein E, YopE" @default.
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• W187320833 doi "https://doi.org/10.1007/0-306-48416-1_81" @default.
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