FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1873658051> ?p ?o ?g. }

• W1873658051 endingPage "236" @default.
• W1873658051 startingPage "224" @default.
• W1873658051 abstract "Despite decades of research, and the growing healthcare and societal burden of chronic obstructive pulmonary disease (COPD), therapeutic COPD breakthroughs have not occurred. Sub-optimal COPD patient phenotyping, an incomplete understanding of COPD pathogenesis and a scarcity of sensitive tools that provide patient-relevant intermediate endpoints likely all play a role in the lack of new, efficacious COPD interventions. In other words, COPD patients are still diagnosed based on the presence of persistent airflow limitation measured using spirometry. Spirometry measurements reflect the global sum of all the different possible COPD pathologies and perhaps because of this, we lose sight of the different contributions of airway and parenchymal abnormalities. With recent advances in thoracic X-ray computed tomography (CT) and magnetic resonance imaging (MRI), lung structure and function abnormalities may be regionally identified and measured. These imaging endpoints may serve as biomarkers of COPD that can be used to better phenotype patients. Therefore, here we review novel CT and MRI measurements that help reveal COPD phenotypes and what COPD really 'looks' like, beyond spirometric indices. We discuss MR and CT imaging approaches for generating reproducible and sensitive measurements of COPD phenotypes related to pulmonary ventilation and perfusion as well as airway and parenchyma anatomical and morphological features. These measurements may provide a way to advance the development and testing of new COPD interventions and therapies." @default.
• W1873658051 created "2016-06-24" @default.
• W1873658051 creator A5006121510 @default.
• W1873658051 creator A5072668158 @default.
• W1873658051 creator A5072863758 @default.
• W1873658051 date "2015-08-26" @default.
• W1873658051 modified "2023-09-26" @default.
• W1873658051 title "<i>This</i> is what <scp>COPD</scp> looks like" @default.
• W1873658051 cites W1480645468 @default.
• W1873658051 cites W1548771082 @default.
• W1873658051 cites W1556612514 @default.
• W1873658051 cites W1602966110 @default.
• W1873658051 cites W160956535 @default.
• W1873658051 cites W1736409832 @default.
• W1873658051 cites W1777171562 @default.
• W1873658051 cites W1892298169 @default.
• W1873658051 cites W1931324049 @default.
• W1873658051 cites W1958194375 @default.
• W1873658051 cites W1965294032 @default.
• W1873658051 cites W1966411814 @default.
• W1873658051 cites W1974102437 @default.
• W1873658051 cites W1986412167 @default.
• W1873658051 cites W1986540339 @default.
• W1873658051 cites W1990835448 @default.
• W1873658051 cites W1994565438 @default.
• W1873658051 cites W1994612769 @default.
• W1873658051 cites W1996223625 @default.
• W1873658051 cites W2001844754 @default.
• W1873658051 cites W2007995867 @default.
• W1873658051 cites W2013383969 @default.
• W1873658051 cites W2018135407 @default.
• W1873658051 cites W2020162806 @default.
• W1873658051 cites W2020707691 @default.
• W1873658051 cites W2022459513 @default.
• W1873658051 cites W2027928218 @default.
• W1873658051 cites W2029310315 @default.
• W1873658051 cites W2035830082 @default.
• W1873658051 cites W2038014686 @default.
• W1873658051 cites W2042902143 @default.
• W1873658051 cites W2045094422 @default.
• W1873658051 cites W2050442457 @default.
• W1873658051 cites W2054404145 @default.
• W1873658051 cites W2057733730 @default.
• W1873658051 cites W2059587208 @default.
• W1873658051 cites W2064641470 @default.
• W1873658051 cites W2065660578 @default.
• W1873658051 cites W2079567903 @default.
• W1873658051 cites W2080034954 @default.
• W1873658051 cites W2080039982 @default.
• W1873658051 cites W2080601435 @default.
• W1873658051 cites W2082907106 @default.
• W1873658051 cites W2087387762 @default.
• W1873658051 cites W2088912872 @default.
• W1873658051 cites W2089742824 @default.
• W1873658051 cites W2093821100 @default.
• W1873658051 cites W2097351207 @default.
• W1873658051 cites W2097659543 @default.
• W1873658051 cites W2102218823 @default.
• W1873658051 cites W2104038900 @default.
• W1873658051 cites W2106781751 @default.
• W1873658051 cites W2112113837 @default.
• W1873658051 cites W2116856128 @default.
• W1873658051 cites W2117489289 @default.
• W1873658051 cites W2119551554 @default.
• W1873658051 cites W2120397327 @default.
• W1873658051 cites W2120833879 @default.
• W1873658051 cites W2122590281 @default.
• W1873658051 cites W2127547306 @default.
• W1873658051 cites W2127951128 @default.
• W1873658051 cites W2129736581 @default.
• W1873658051 cites W2130384788 @default.
• W1873658051 cites W2133464295 @default.
• W1873658051 cites W2135002409 @default.
• W1873658051 cites W2139131213 @default.
• W1873658051 cites W2139391374 @default.
• W1873658051 cites W2139507936 @default.
• W1873658051 cites W2140461832 @default.
• W1873658051 cites W2145200901 @default.
• W1873658051 cites W2145276357 @default.
• W1873658051 cites W2145466675 @default.
• W1873658051 cites W2153364064 @default.
• W1873658051 cites W2153423130 @default.
• W1873658051 cites W2155662634 @default.
• W1873658051 cites W2163267243 @default.
• W1873658051 cites W2171506107 @default.
• W1873658051 cites W2171647346 @default.
• W1873658051 cites W2291379829 @default.
• W1873658051 cites W4251615963 @default.
• W1873658051 cites W4297903471 @default.
• W1873658051 doi "https://doi.org/10.1111/resp.12611" @default.
• W1873658051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26333307" @default.
• W1873658051 hasPublicationYear "2015" @default.
• W1873658051 type Work @default.
• W1873658051 sameAs 1873658051 @default.
• W1873658051 citedByCount "42" @default.
• W1873658051 countsByYear W18736580512016 @default.
• W1873658051 countsByYear W18736580512017 @default.
• W1873658051 countsByYear W18736580512018 @default.

• next