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• W1874214683 abstract "Publisher Summary Zebrafish has been successfully used to analyze embryonic development and organogenesis. In particular, large-scale genetic screens, which have propelled the Zebrafish to scientific prominence, demonstrate that an entire vertebrate genome can be analyzed in detail using random mutagenesis. The isolated mutants have already significantly contributed to the understanding of early vertebrate development and organogenesis. Zebrafish are uniquely capable of being utilized to carry out forward genetic screens and study genes using a host of reverse genetic approaches. Gene overexpression and knockdown techniques are routinely used and have greatly added to current understanding of molecular mechanisms. As connections between development and human disease become more apparent, increased emphasis will be placed on understanding the basic biology of organ development. Because of the many features that make the Zebrafish attractive to study organogenesis, its importance in unraveling pathways and genes involved in organ development will undoubtedly grow. As unlikely as it may seem at first glance, the use of the Zebrafish as a model organism lead to the identification of novel targets for therapeutic intervention and treatments for human disease." @default.
• W1874214683 created "2016-06-24" @default.
• W1874214683 creator A5007729049 @default.
• W1874214683 creator A5059172937 @default.
• W1874214683 creator A5073785005 @default.
• W1874214683 date "2004-01-01" @default.
• W1874214683 modified "2023-09-23" @default.
• W1874214683 title "From Guts to Brains: Using Zebrafish Genetics to Understand the Innards of Organogenesis" @default.
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