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- W1874475329 abstract "Considering the optimal alignment of two i.i.d. random sequences of length $n$, we show that when the scoring function is chosen randomly, almost surely the empirical distribution of aligned letter pairs in all optimal alignments converges to a unique limiting distribution as $n$ tends to infinity. This result is interesting because it helps understanding the microscopic path structure of a special type of last passage percolation problem with correlated weights, an area of long-standing open problems. Characterizing the microscopic path structure yields furthermore a robust alternative to optimal alignment scores for testing the relatedness of genetic sequences." @default.
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- W1874475329 date "2012-11-23" @default.
- W1874475329 modified "2023-09-22" @default.
- W1874475329 title "Distribution of Aligned Letter Pairs in Optimal Alignments of Random Sequences" @default.
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