Matches in SemOpenAlex for { <https://semopenalex.org/work/W1875175558> ?p ?o ?g. }
- W1875175558 endingPage "258" @default.
- W1875175558 startingPage "244" @default.
- W1875175558 abstract "Tissue thinning and spreading, a morphogenetic movement termed epiboly, is used widely during animal development. In zebrafish, epiboly is a prominent cell movement during gastrulation, whereby a squamous epithelium (the enveloping layer), a multi-layer of loosely packed cells (the deep cells), and a yolk nuclear syncytium (the yolk syncytial layer) undergo coordinated expansion to engulf the yolk and close the blastopore. Elucidating the mechanisms that underlie epiboly is important not only for understanding animal development in general, but also for providing insights into fundamental cell behaviors including cell intercalation, cell adhesion, cell signaling, and epithelial morphogenesis. Here, recent work is reviewed with a focus on findings that advance our understanding of (1) the role of actomyosin motors in the yolk cell to drive epiboly, (2) the mechanisms that underlie the spreading of the epithelial enveloping layer, and (3) the regulation of deep cell movements by E-cadherin based adhesion. A discussion of how these new insights add to the current view of epiboly and future prospects is also presented. Overall, the study of zebrafish epiboly can provide general and broadly applicable insights into the genetic, molecular, and cellular control of morphogenesis." @default.
- W1875175558 created "2016-06-24" @default.
- W1875175558 creator A5002127292 @default.
- W1875175558 date "2015-10-28" @default.
- W1875175558 modified "2023-10-06" @default.
- W1875175558 title "Zebrafish epiboly: Spreading thin over the yolk" @default.
- W1875175558 cites W1528309942 @default.
- W1875175558 cites W1545772717 @default.
- W1875175558 cites W1595083713 @default.
- W1875175558 cites W1602754405 @default.
- W1875175558 cites W1625114030 @default.
- W1875175558 cites W1755300801 @default.
- W1875175558 cites W1959073095 @default.
- W1875175558 cites W1961074127 @default.
- W1875175558 cites W1963558962 @default.
- W1875175558 cites W1963826137 @default.
- W1875175558 cites W1964671479 @default.
- W1875175558 cites W1966704740 @default.
- W1875175558 cites W1971987459 @default.
- W1875175558 cites W1976391205 @default.
- W1875175558 cites W1978806262 @default.
- W1875175558 cites W1983460993 @default.
- W1875175558 cites W1985999273 @default.
- W1875175558 cites W1986394211 @default.
- W1875175558 cites W1986433824 @default.
- W1875175558 cites W1986646687 @default.
- W1875175558 cites W1987279648 @default.
- W1875175558 cites W1987300109 @default.
- W1875175558 cites W1996436456 @default.
- W1875175558 cites W1998287390 @default.
- W1875175558 cites W1999731577 @default.
- W1875175558 cites W2001183171 @default.
- W1875175558 cites W2001449914 @default.
- W1875175558 cites W2001609703 @default.
- W1875175558 cites W2003526213 @default.
- W1875175558 cites W2004081285 @default.
- W1875175558 cites W2004283021 @default.
- W1875175558 cites W2006664822 @default.
- W1875175558 cites W2006758304 @default.
- W1875175558 cites W2007797957 @default.
- W1875175558 cites W2009908021 @default.
- W1875175558 cites W2011916521 @default.
- W1875175558 cites W2014809662 @default.
- W1875175558 cites W2017065102 @default.
- W1875175558 cites W2017693326 @default.
- W1875175558 cites W2020588469 @default.
- W1875175558 cites W2021232061 @default.
- W1875175558 cites W2024819483 @default.
- W1875175558 cites W2026226466 @default.
- W1875175558 cites W2028659881 @default.
- W1875175558 cites W2032930150 @default.
- W1875175558 cites W2035075323 @default.
- W1875175558 cites W2039137573 @default.
- W1875175558 cites W2041677910 @default.
- W1875175558 cites W2042551507 @default.
- W1875175558 cites W2044911975 @default.
- W1875175558 cites W2049368206 @default.
- W1875175558 cites W2050064867 @default.
- W1875175558 cites W2050286713 @default.
- W1875175558 cites W2054132545 @default.
- W1875175558 cites W2054717718 @default.
- W1875175558 cites W2054940555 @default.
- W1875175558 cites W2056908201 @default.
- W1875175558 cites W2058525645 @default.
- W1875175558 cites W2060772796 @default.
- W1875175558 cites W2061927929 @default.
- W1875175558 cites W2069838915 @default.
- W1875175558 cites W2072275890 @default.
- W1875175558 cites W2072901983 @default.
- W1875175558 cites W2074572575 @default.
- W1875175558 cites W2081155310 @default.
- W1875175558 cites W2082839015 @default.
- W1875175558 cites W2089491135 @default.
- W1875175558 cites W2089613312 @default.
- W1875175558 cites W2092032317 @default.
- W1875175558 cites W2096051459 @default.
- W1875175558 cites W2099442298 @default.
- W1875175558 cites W2108575498 @default.
- W1875175558 cites W2109461200 @default.
- W1875175558 cites W2121948301 @default.
- W1875175558 cites W2123723680 @default.
- W1875175558 cites W2123787611 @default.
- W1875175558 cites W2125349610 @default.
- W1875175558 cites W2125522271 @default.
- W1875175558 cites W2125983595 @default.
- W1875175558 cites W2129502556 @default.
- W1875175558 cites W2132204920 @default.
- W1875175558 cites W2132581785 @default.
- W1875175558 cites W2132697535 @default.
- W1875175558 cites W2136963255 @default.
- W1875175558 cites W2140384676 @default.
- W1875175558 cites W2141122881 @default.
- W1875175558 cites W2144815801 @default.
- W1875175558 cites W2149361658 @default.
- W1875175558 cites W2151103961 @default.
- W1875175558 cites W2154318942 @default.
- W1875175558 cites W2155292382 @default.
- W1875175558 cites W2156012303 @default.