Matches in SemOpenAlex for { <https://semopenalex.org/work/W1877180868> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1877180868 endingPage "387" @default.
- W1877180868 startingPage "376" @default.
- W1877180868 abstract "With the availability of hundreds and soon thousands of complete genomes, the construction of genome-scale metabolic models for these organisms has attracted much attention. Manual work still dominates the process of model generation, however, and leads to the huge gap between the number of complete genomes and genome-scale metabolic models. The challenge in constructing genome-scale models from existing databases is that usually such a directly extracted model is incomplete and contains network holes. Network holes occur when a network is disconnected and certain metabolites cannot be produced or consumed. In order to construct a valid metabolic model, network holes need to be filled by introducing candidate reactions into the network. As a step toward the high-throughput generation of biological models, we propose a Bayesian approach to improving draft genome-scale metabolic models. A collection of 23 types of biological and topological evidence is extracted from the SEED [1], KEGG [2], and BiGG [3] databases. Based on this evidence, we create 23 individual predictors using Bayesian approaches. To combine these individual predictors and unify their predictive results, we build an ensemble of individual predictors on majority vote and four classifiers: naive Bayes classifier, Bayesian network, multilayer perceptron network and AdaBoost. A set of experiments is performed to train and test individual predictors and integrative mechanisms of single predictors and to evaluate the performance of our approach." @default.
- W1877180868 created "2016-06-24" @default.
- W1877180868 creator A5053682943 @default.
- W1877180868 creator A5055295290 @default.
- W1877180868 date "2009-01-01" @default.
- W1877180868 modified "2023-10-18" @default.
- W1877180868 title "A Bayesian Approach to High-Throughput Biological Model Generation" @default.
- W1877180868 cites W1543388089 @default.
- W1877180868 cites W1603241183 @default.
- W1877180868 cites W1814099126 @default.
- W1877180868 cites W2004548026 @default.
- W1877180868 cites W2010075076 @default.
- W1877180868 cites W2010579377 @default.
- W1877180868 cites W2086016524 @default.
- W1877180868 cites W2096245011 @default.
- W1877180868 cites W2111031006 @default.
- W1877180868 cites W2114034054 @default.
- W1877180868 cites W2115542536 @default.
- W1877180868 cites W2119215577 @default.
- W1877180868 cites W2122638857 @default.
- W1877180868 cites W2123060905 @default.
- W1877180868 cites W2126175129 @default.
- W1877180868 cites W4256259619 @default.
- W1877180868 doi "https://doi.org/10.1007/978-3-642-00727-9_35" @default.
- W1877180868 hasPublicationYear "2009" @default.
- W1877180868 type Work @default.
- W1877180868 sameAs 1877180868 @default.
- W1877180868 citedByCount "0" @default.
- W1877180868 crossrefType "book-chapter" @default.
- W1877180868 hasAuthorship W1877180868A5053682943 @default.
- W1877180868 hasAuthorship W1877180868A5055295290 @default.
- W1877180868 hasBestOaLocation W18771808682 @default.
- W1877180868 hasConcept C101810790 @default.
- W1877180868 hasConcept C104317684 @default.
- W1877180868 hasConcept C107673813 @default.
- W1877180868 hasConcept C119857082 @default.
- W1877180868 hasConcept C12267149 @default.
- W1877180868 hasConcept C124101348 @default.
- W1877180868 hasConcept C141231307 @default.
- W1877180868 hasConcept C154945302 @default.
- W1877180868 hasConcept C179717631 @default.
- W1877180868 hasConcept C207201462 @default.
- W1877180868 hasConcept C28225019 @default.
- W1877180868 hasConcept C33724603 @default.
- W1877180868 hasConcept C41008148 @default.
- W1877180868 hasConcept C50644808 @default.
- W1877180868 hasConcept C52001869 @default.
- W1877180868 hasConcept C54355233 @default.
- W1877180868 hasConcept C60908668 @default.
- W1877180868 hasConcept C70721500 @default.
- W1877180868 hasConcept C86803240 @default.
- W1877180868 hasConcept C95623464 @default.
- W1877180868 hasConceptScore W1877180868C101810790 @default.
- W1877180868 hasConceptScore W1877180868C104317684 @default.
- W1877180868 hasConceptScore W1877180868C107673813 @default.
- W1877180868 hasConceptScore W1877180868C119857082 @default.
- W1877180868 hasConceptScore W1877180868C12267149 @default.
- W1877180868 hasConceptScore W1877180868C124101348 @default.
- W1877180868 hasConceptScore W1877180868C141231307 @default.
- W1877180868 hasConceptScore W1877180868C154945302 @default.
- W1877180868 hasConceptScore W1877180868C179717631 @default.
- W1877180868 hasConceptScore W1877180868C207201462 @default.
- W1877180868 hasConceptScore W1877180868C28225019 @default.
- W1877180868 hasConceptScore W1877180868C33724603 @default.
- W1877180868 hasConceptScore W1877180868C41008148 @default.
- W1877180868 hasConceptScore W1877180868C50644808 @default.
- W1877180868 hasConceptScore W1877180868C52001869 @default.
- W1877180868 hasConceptScore W1877180868C54355233 @default.
- W1877180868 hasConceptScore W1877180868C60908668 @default.
- W1877180868 hasConceptScore W1877180868C70721500 @default.
- W1877180868 hasConceptScore W1877180868C86803240 @default.
- W1877180868 hasConceptScore W1877180868C95623464 @default.
- W1877180868 hasLocation W18771808681 @default.
- W1877180868 hasLocation W18771808682 @default.
- W1877180868 hasOpenAccess W1877180868 @default.
- W1877180868 hasPrimaryLocation W18771808681 @default.
- W1877180868 hasRelatedWork W1506481126 @default.
- W1877180868 hasRelatedWork W1599577651 @default.
- W1877180868 hasRelatedWork W2016517455 @default.
- W1877180868 hasRelatedWork W2979979539 @default.
- W1877180868 hasRelatedWork W3165520694 @default.
- W1877180868 hasRelatedWork W3168994312 @default.
- W1877180868 hasRelatedWork W3185179407 @default.
- W1877180868 hasRelatedWork W4249229055 @default.
- W1877180868 hasRelatedWork W4280611221 @default.
- W1877180868 hasRelatedWork W4316082230 @default.
- W1877180868 isParatext "false" @default.
- W1877180868 isRetracted "false" @default.
- W1877180868 magId "1877180868" @default.
- W1877180868 workType "book-chapter" @default.