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- W187719115 abstract "Quercetin, kaempferol and to a lesser extent rutin have been reported to have antidiabetic activities when assessed by various assay models including in vitro α-glucosidase inhibition studies. A related structural analogue, kaempferol-3- O-rutinoside (KR) however has not yet been studied for such biological effects. It was found that KR is a potent inhibitor of α-glucosidase in vitro with over 8-times more activity than the reference antidiabetic drug, acarbose. Furthermore, KR displayed a synergistic effect with a less potent flavonoid aglycones, kaempferol and quercetin. The structure-activity profile of these drugs and implications of drug combinations are discussed." @default.
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- W187719115 date "2011-02-01" @default.
- W187719115 modified "2023-10-15" @default.
- W187719115 title "α-Glucosidase Inhibitory Activity of Kaempferol-3-<i>O</i>-rutinoside" @default.
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- W187719115 doi "https://doi.org/10.1177/1934578x1100600211" @default.
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