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- W187817875 abstract "Purpose: The clinical problem of cervical dentinal hypersensitivity (CDS) can be managed by strategies that occlude patent dentine tubules exposed to the oral environment, or that reduce the excitability of pulpal nerves. Materials and methods: This randomized clinical trial with 89 subjects (53 from private practice and 36 from public sector dental clinics) compared the therapeutic effect of a 10% CPP-ACP creme (GC Tooth Mousse) applied topically each night before retiring in conjunction with a conventional dentifrice twice daily, to the twice daily use of an established potassium nitrate dentifrice (Colgate Sensitive). Treatments were used over 6 weeks, and this was followed by a 4 week washout period. CDS responses to 4 types of stimuli were self-rated using a visual-analogue scale at 4, 6, and 10 weeks, and a composite CDS score calculated. All data were analyzed in a blinded manner. Results: The two treatment groups were well matched with no significance difference in baseline scores. In both the CPP-ACP and potassium nitrate groups, when compared with their relevant baseline values, CDS scores were reduced significantly at 4 weeks when assessed using a repeated measures ANOVA (P<0.02). This effect was sustained at 6 weeks, and across the ensuing 4 week washout period. At all time points, there was no significant difference between the two treatment groups. The reduction in CDS scores was more pronounced in public sector dental patients than in those drawn from private practice. Conclusions: Despite differences in their apparent mechanisms of action, both CPP-ACP creme and the potassium nitrate dentifrice gave similar clinically useful reductions in CDS." @default.
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- W187817875 date "2010-01-01" @default.
- W187817875 modified "2023-09-26" @default.
- W187817875 title "The effects of GC Tooth Mousse on cervical dentinal sensitivity: A controlled clinical trial" @default.
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