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- W1878362608 abstract "This chapter discusses progress in cerebral microvascular studies related to the function of the blood–brain barrier (BBB). It is generally accepted that the cerebral microvessels are an integral part of the BBB. However, the extent of micro vascular participation and the mechanisms responsible for some of the BBB phenomena have been difficult to evaluate in the in vivo studies because of the concomitant influence of other cerebral elements. The recent available techniques for the isolation of cerebral microvessels and the establishment of pure endothelial cell cultures provide a model for the investigation of their properties and function separately from the rest of the brain. The chapter describes the method and properties of cerebral endothelial cell cultures derived from isolated cerebral microvessels. It also discusses the available information concerning the properties and function of isolated cerebral microvessels, especially in relation to the BBB, based on old and new findings." @default.
- W1878362608 created "2016-06-24" @default.
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- W1878362608 date "1982-01-01" @default.
- W1878362608 modified "2023-10-18" @default.
- W1878362608 title "Progress in Cerebral Microvascular Studies Related to the Function of the Blood-Brain Barrier" @default.
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- W1878362608 doi "https://doi.org/10.1016/b978-0-12-008303-9.50014-1" @default.
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