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• W1878780595 abstract "White TiO2 nanoparticles (NPs) have been widely used for cancer photodynamic therapy based on their ultraviolet light-triggered properties. To date, biomedical applications using white TiO2 NPs have been limited, since ultraviolet light is a well-known mutagen and shallow penetration. This work is the first report about hydrogenated black TiO2 (H-TiO2 ) NPs with near infrared absorption explored as photothermal agent for cancer photothermal therapy to circumvent the obstacle of ultraviolet light excitation. Here, it is shown that photothermal effect of H-TiO2 NPs can be attributed to their dramatically enhanced nonradiative recombination. After polyethylene glycol (PEG) coating, H-TiO2 -PEG NPs exhibit high photothermal conversion efficiency of 40.8%, and stable size distribution in serum solution. The toxicity and cancer therapy effect of H-TiO2 -PEG NPs are relative systemically evaluated in vitro and in vivo. The findings herein demonstrate that infrared-irradiated H-TiO2 -PEG NPs exhibit low toxicity, high efficiency as a photothermal agent for cancer therapy, and are promising for further biomedical applications." @default.
• W1878780595 created "2016-06-24" @default.
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• W1878780595 date "2015-05-26" @default.
• W1878780595 modified "2023-10-10" @default.
• W1878780595 title "A Near Infrared Light Triggered Hydrogenated Black TiO₂for Cancer Photothermal Therapy" @default.
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• W1878780595 doi "https://doi.org/10.1002/adhm.201500273" @default.
• W1878780595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26010821" @default.
• W1878780595 hasPublicationYear "2015" @default.
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