FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1878962892> ?p ?o ?g. }

• W1878962892 abstract "Dietary trans-resveratrol (RES) is rapidly metabolized into sulfated and glucuronated conjugates in humans. This study focused on the in vitro determination of the antioxidant capacity of RES and its main physiological metabolites and on its relevance in vivo. In vitro, RES, RES-3-O-sulfate (R3S) and 3-O-glucuronide (R3G) showed antioxidant activities at a concentration of 1mM when compared to Trolox using an assay in which the antioxidant inhibits iron-induced linoleic acid oxidation: 0.87±0.08mM Trolox equivalents (TE) for RES, 0.52±0.01mM TE for R3S and 0.36±0.02mM TE for R3G. At a concentration of 1μM, compounds promoted linoleic acid peroxidation (RES -0.30±0.09mM TE, R3S -0.48±0.05mM TE and R3G -0.57±0.07mM TE). To elucidate whether these effects were reflected in vivo, total antioxidant capacity, reactive oxygen species (ROS), conjugated fatty acid dienes (CD), superoxide dismutase (SOD) and catalase (CAT) activities were determined in human plasma and erythrocytes over 24h, after oral intake of either 0.05g RES as piceid or 5g RES. Oral administration of RES did not show an impact on total antioxidant capacity, ROS or CD. However, enzymatic activities of ROS scavenging SOD and CAT were significantly lower after high-dose compared to low-dose administration of RES (P<.03 and P<.01). In conclusion, in healthy subjects, neither 0.05g nor 5g RES changed blood oxidative state, although our in vitro data point to a prooxidative activity of low concentrations of RES and its metabolites, which could be important in vivo for individuals with compromised antioxidant defense capacity." @default.
• W1878962892 created "2016-06-24" @default.
• W1878962892 creator A5000025423 @default.
• W1878962892 creator A5000537301 @default.
• W1878962892 creator A5004292301 @default.
• W1878962892 creator A5025690696 @default.
• W1878962892 creator A5026514914 @default.
• W1878962892 creator A5054404247 @default.
• W1878962892 creator A5067554823 @default.
• W1878962892 creator A5091836832 @default.
• W1878962892 date "2016-01-01" @default.
• W1878962892 modified "2023-09-29" @default.
• W1878962892 title "Concentration-dependent effects of resveratrol and metabolites on the redox status of human erythrocytes in single-dose studies" @default.
• W1878962892 cites W191793640 @default.
• W1878962892 cites W1963978740 @default.
• W1878962892 cites W1965234101 @default.
• W1878962892 cites W1967964480 @default.
• W1878962892 cites W1974814867 @default.
• W1878962892 cites W1977155630 @default.
• W1878962892 cites W1984829837 @default.
• W1878962892 cites W1987927672 @default.
• W1878962892 cites W1995665560 @default.
• W1878962892 cites W1996054359 @default.
• W1878962892 cites W2000682020 @default.
• W1878962892 cites W2007406202 @default.
• W1878962892 cites W2007492343 @default.
• W1878962892 cites W2007541295 @default.
• W1878962892 cites W2019447370 @default.
• W1878962892 cites W2035330181 @default.
• W1878962892 cites W2038796223 @default.
• W1878962892 cites W2039611002 @default.
• W1878962892 cites W2045309171 @default.
• W1878962892 cites W2050625990 @default.
• W1878962892 cites W2053542354 @default.
• W1878962892 cites W2060046111 @default.
• W1878962892 cites W2060220831 @default.
• W1878962892 cites W2086196309 @default.
• W1878962892 cites W2088934129 @default.
• W1878962892 cites W2093770918 @default.
• W1878962892 cites W2096660213 @default.
• W1878962892 cites W2104525350 @default.
• W1878962892 cites W2117499294 @default.
• W1878962892 cites W2118315807 @default.
• W1878962892 cites W2128001813 @default.
• W1878962892 cites W2151440119 @default.
• W1878962892 cites W2152036317 @default.
• W1878962892 cites W2153281249 @default.
• W1878962892 cites W2154949516 @default.
• W1878962892 cites W2155590575 @default.
• W1878962892 cites W2168526937 @default.
• W1878962892 cites W2183041667 @default.
• W1878962892 cites W2201036107 @default.
• W1878962892 cites W2332117966 @default.
• W1878962892 cites W3149349019 @default.
• W1878962892 cites W384863521 @default.
• W1878962892 doi "https://doi.org/10.1016/j.jnutbio.2015.08.032" @default.
• W1878962892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26454510" @default.
• W1878962892 hasPublicationYear "2016" @default.
• W1878962892 type Work @default.
• W1878962892 sameAs 1878962892 @default.
• W1878962892 citedByCount "11" @default.
• W1878962892 countsByYear W18789628922016 @default.
• W1878962892 countsByYear W18789628922017 @default.
• W1878962892 countsByYear W18789628922018 @default.
• W1878962892 countsByYear W18789628922019 @default.
• W1878962892 countsByYear W18789628922020 @default.
• W1878962892 countsByYear W18789628922021 @default.
• W1878962892 crossrefType "journal-article" @default.
• W1878962892 hasAuthorship W1878962892A5000025423 @default.
• W1878962892 hasAuthorship W1878962892A5000537301 @default.
• W1878962892 hasAuthorship W1878962892A5004292301 @default.
• W1878962892 hasAuthorship W1878962892A5025690696 @default.
• W1878962892 hasAuthorship W1878962892A5026514914 @default.
• W1878962892 hasAuthorship W1878962892A5054404247 @default.
• W1878962892 hasAuthorship W1878962892A5067554823 @default.
• W1878962892 hasAuthorship W1878962892A5091836832 @default.
• W1878962892 hasBestOaLocation W18789628921 @default.
• W1878962892 hasConcept C150903083 @default.
• W1878962892 hasConcept C185592680 @default.
• W1878962892 hasConcept C207001950 @default.
• W1878962892 hasConcept C2775838275 @default.
• W1878962892 hasConcept C2776231299 @default.
• W1878962892 hasConcept C2776816829 @default.
• W1878962892 hasConcept C2778004101 @default.
• W1878962892 hasConcept C2778979269 @default.
• W1878962892 hasConcept C2779780233 @default.
• W1878962892 hasConcept C2780809830 @default.
• W1878962892 hasConcept C2780829032 @default.
• W1878962892 hasConcept C2993539680 @default.
• W1878962892 hasConcept C48349386 @default.
• W1878962892 hasConcept C543025807 @default.
• W1878962892 hasConcept C55493867 @default.
• W1878962892 hasConcept C86803240 @default.
• W1878962892 hasConcept C98274493 @default.
• W1878962892 hasConceptScore W1878962892C150903083 @default.
• W1878962892 hasConceptScore W1878962892C185592680 @default.
• W1878962892 hasConceptScore W1878962892C207001950 @default.
• W1878962892 hasConceptScore W1878962892C2775838275 @default.
• W1878962892 hasConceptScore W1878962892C2776231299 @default.
• W1878962892 hasConceptScore W1878962892C2776816829 @default.

• next