FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1879202914> ?p ?o ?g. }

• W1879202914 endingPage "202" @default.
• W1879202914 startingPage "196" @default.
• W1879202914 abstract "Calu-3 cells, a human lung carcinoma cell line with properties like serous cells of the upper airway, were used to develop an in vitro model for airway antibacterial activity. Calu-3 cell monolayers were cultured on permeable supports at an air-liquid interface. Apical surface fluid (ASF) was collected by washing; antibacterial activity was assayed by incubating ASF washings with bacteria for 18 h and counting surviving colony-forming units. ASF washings killed Escherichia coli and Pseudomonas aeruginosa. Antibacterial activity was salt sensitive and dependent on protein concentration. After washing, approximately 30 h were required before antibacterial activity recovered to its initial level. After culturing with topical corticosteroids (budesonide, triamcinolone, or beclomethasone, 0.1 microg/ml for 48 h), ASF antibacterial activity was 4- to 10-fold greater than the ASF from control monolayers. The increase in antibacterial activity was dose-dependent. The beta(2)-agonists salbutamol and terbutaline (100 microg/ml for 48 h) decreased ASF antibacterial activity by 5- to 8-fold. The nonsteroidal anti-inflammatory agents ibuprofen and cromolyn sodium had no effect. Our results are most consistent with agonist-dependent changes in the composition of ASF antibacterial proteins. We conclude that Calu-3 cells synthesize and secrete antibacterial proteins and that clinical agents can alter these functions." @default.
• W1879202914 created "2016-06-24" @default.
• W1879202914 creator A5024562321 @default.
• W1879202914 creator A5044544424 @default.
• W1879202914 creator A5090796140 @default.
• W1879202914 date "2001-08-01" @default.
• W1879202914 modified "2023-09-27" @default.
• W1879202914 title "Antibacterial Activity of Apical Surface Fluid from the Human Airway Cell Line Calu-3" @default.
• W1879202914 cites W1969971789 @default.
• W1879202914 cites W1974216262 @default.
• W1879202914 cites W1981406037 @default.
• W1879202914 cites W1981933466 @default.
• W1879202914 cites W1985191154 @default.
• W1879202914 cites W1995053645 @default.
• W1879202914 cites W1998413155 @default.
• W1879202914 cites W2004907878 @default.
• W1879202914 cites W2007415402 @default.
• W1879202914 cites W2022634662 @default.
• W1879202914 cites W2023746910 @default.
• W1879202914 cites W2031005159 @default.
• W1879202914 cites W2046354137 @default.
• W1879202914 cites W2058223359 @default.
• W1879202914 cites W2059361679 @default.
• W1879202914 cites W2061117470 @default.
• W1879202914 cites W2065273951 @default.
• W1879202914 cites W2078920860 @default.
• W1879202914 cites W2097098774 @default.
• W1879202914 cites W2098768419 @default.
• W1879202914 cites W2102730957 @default.
• W1879202914 cites W2108043979 @default.
• W1879202914 cites W2145517314 @default.
• W1879202914 cites W2147049357 @default.
• W1879202914 cites W2155345300 @default.
• W1879202914 cites W2167403314 @default.
• W1879202914 cites W2336210752 @default.
• W1879202914 doi "https://doi.org/10.1165/ajrcmb.25.2.4211" @default.
• W1879202914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11509329" @default.
• W1879202914 hasPublicationYear "2001" @default.
• W1879202914 type Work @default.
• W1879202914 sameAs 1879202914 @default.
• W1879202914 citedByCount "29" @default.
• W1879202914 countsByYear W18792029142012 @default.
• W1879202914 countsByYear W18792029142013 @default.
• W1879202914 countsByYear W18792029142015 @default.
• W1879202914 countsByYear W18792029142017 @default.
• W1879202914 countsByYear W18792029142018 @default.
• W1879202914 countsByYear W18792029142019 @default.
• W1879202914 countsByYear W18792029142020 @default.
• W1879202914 countsByYear W18792029142021 @default.
• W1879202914 countsByYear W18792029142022 @default.
• W1879202914 countsByYear W18792029142023 @default.
• W1879202914 crossrefType "journal-article" @default.
• W1879202914 hasAuthorship W1879202914A5024562321 @default.
• W1879202914 hasAuthorship W1879202914A5044544424 @default.
• W1879202914 hasAuthorship W1879202914A5090796140 @default.
• W1879202914 hasConcept C104317684 @default.
• W1879202914 hasConcept C153911025 @default.
• W1879202914 hasConcept C178790620 @default.
• W1879202914 hasConcept C185592680 @default.
• W1879202914 hasConcept C2778996431 @default.
• W1879202914 hasConcept C2780104969 @default.
• W1879202914 hasConcept C3019249092 @default.
• W1879202914 hasConcept C501593827 @default.
• W1879202914 hasConcept C523546767 @default.
• W1879202914 hasConcept C54355233 @default.
• W1879202914 hasConcept C547475151 @default.
• W1879202914 hasConcept C55493867 @default.
• W1879202914 hasConcept C81885089 @default.
• W1879202914 hasConcept C86803240 @default.
• W1879202914 hasConcept C89423630 @default.
• W1879202914 hasConcept C98274493 @default.
• W1879202914 hasConceptScore W1879202914C104317684 @default.
• W1879202914 hasConceptScore W1879202914C153911025 @default.
• W1879202914 hasConceptScore W1879202914C178790620 @default.
• W1879202914 hasConceptScore W1879202914C185592680 @default.
• W1879202914 hasConceptScore W1879202914C2778996431 @default.
• W1879202914 hasConceptScore W1879202914C2780104969 @default.
• W1879202914 hasConceptScore W1879202914C3019249092 @default.
• W1879202914 hasConceptScore W1879202914C501593827 @default.
• W1879202914 hasConceptScore W1879202914C523546767 @default.
• W1879202914 hasConceptScore W1879202914C54355233 @default.
• W1879202914 hasConceptScore W1879202914C547475151 @default.
• W1879202914 hasConceptScore W1879202914C55493867 @default.
• W1879202914 hasConceptScore W1879202914C81885089 @default.
• W1879202914 hasConceptScore W1879202914C86803240 @default.
• W1879202914 hasConceptScore W1879202914C89423630 @default.
• W1879202914 hasConceptScore W1879202914C98274493 @default.
• W1879202914 hasIssue "2" @default.
• W1879202914 hasLocation W18792029141 @default.
• W1879202914 hasLocation W18792029142 @default.
• W1879202914 hasOpenAccess W1879202914 @default.
• W1879202914 hasPrimaryLocation W18792029141 @default.
• W1879202914 hasRelatedWork W2036347073 @default.
• W1879202914 hasRelatedWork W2061297944 @default.
• W1879202914 hasRelatedWork W2076614389 @default.
• W1879202914 hasRelatedWork W2795634977 @default.
• W1879202914 hasRelatedWork W2898274243 @default.
• W1879202914 hasRelatedWork W3020915007 @default.

• next