Matches in SemOpenAlex for { <https://semopenalex.org/work/W1879944265> ?p ?o ?g. }
- W1879944265 endingPage "458s" @default.
- W1879944265 startingPage "456s" @default.
- W1879944265 abstract "Several nondigestible but fermentable dietary carbohydrates are able to regulate lipemia and triglyceridemia in both humans and animals. The mechanism of their serum lipid-lowering effect remains to be elucidated. Oligofructose, which is a mixture of nondigestible and fermentable fructans, can decrease triacylglycerol in VLDL when given to rats. The triacylglycerol-lowering action of oligofructose is due to a reduction of de novo fatty acid synthesis in the liver through inhibition of all lipogenic enzymes, namely acetyl-CoA carboxylase (EC 6.4.1.2), fatty acid synthase, malic enzyme (EC 1.1.1.40), ATP citrate lyase (EC 4.1.3.8), and glucose-6-phosphate dehydrogenase (EC 1.1.1.49). Our results suggest that oligofructose decreases lipogenic enzyme gene expression. Postprandial insulin and glucose concentrations are low in the serum of oligofructose-fed animals and this could explain, at least partially, the metabolic effect of oligofructose. Moreover, some events occurring in the gastrointestinal tract after oligofructose feeding could be involved in the antilipogenic effect of this fructan: the production of propionate through fermentation, a modulation of the intestinal production of incretins (namely glucose-dependent insulinotropic peptide and glucagon-like peptide-1), or the modification of the availability of digestible carbohydrates. Recent studies showed that the hypotriglyceridemic effect of fructans also occurs in humans." @default.
- W1879944265 created "2016-06-24" @default.
- W1879944265 creator A5009659727 @default.
- W1879944265 creator A5029648123 @default.
- W1879944265 date "2001-02-01" @default.
- W1879944265 modified "2023-10-16" @default.
- W1879944265 title "Effects of fructans-type prebiotics on lipid metabolism" @default.
- W1879944265 cites W1773263217 @default.
- W1879944265 cites W1813690525 @default.
- W1879944265 cites W2009094549 @default.
- W1879944265 cites W2016617572 @default.
- W1879944265 cites W2020916024 @default.
- W1879944265 cites W2022934952 @default.
- W1879944265 cites W2047589729 @default.
- W1879944265 cites W2051711682 @default.
- W1879944265 cites W2056221656 @default.
- W1879944265 cites W2060409973 @default.
- W1879944265 cites W2065094293 @default.
- W1879944265 cites W2067972685 @default.
- W1879944265 cites W2069240962 @default.
- W1879944265 cites W2078245285 @default.
- W1879944265 cites W2093014027 @default.
- W1879944265 cites W2094130134 @default.
- W1879944265 cites W2095913945 @default.
- W1879944265 cites W2100069519 @default.
- W1879944265 cites W2122444611 @default.
- W1879944265 cites W2141122773 @default.
- W1879944265 cites W2143514776 @default.
- W1879944265 cites W2149935651 @default.
- W1879944265 cites W2152593520 @default.
- W1879944265 cites W21551744 @default.
- W1879944265 cites W2159349197 @default.
- W1879944265 cites W2163286174 @default.
- W1879944265 cites W2171142773 @default.
- W1879944265 cites W2171642996 @default.
- W1879944265 cites W2289246341 @default.
- W1879944265 cites W2296712413 @default.
- W1879944265 cites W2304844659 @default.
- W1879944265 cites W4212832781 @default.
- W1879944265 doi "https://doi.org/10.1093/ajcn/73.2.456s" @default.
- W1879944265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11157357" @default.
- W1879944265 hasPublicationYear "2001" @default.
- W1879944265 type Work @default.
- W1879944265 sameAs 1879944265 @default.
- W1879944265 citedByCount "193" @default.
- W1879944265 countsByYear W18799442652012 @default.
- W1879944265 countsByYear W18799442652013 @default.
- W1879944265 countsByYear W18799442652014 @default.
- W1879944265 countsByYear W18799442652015 @default.
- W1879944265 countsByYear W18799442652016 @default.
- W1879944265 countsByYear W18799442652017 @default.
- W1879944265 countsByYear W18799442652018 @default.
- W1879944265 countsByYear W18799442652019 @default.
- W1879944265 countsByYear W18799442652020 @default.
- W1879944265 countsByYear W18799442652021 @default.
- W1879944265 countsByYear W18799442652022 @default.
- W1879944265 countsByYear W18799442652023 @default.
- W1879944265 crossrefType "journal-article" @default.
- W1879944265 hasAuthorship W1879944265A5009659727 @default.
- W1879944265 hasAuthorship W1879944265A5029648123 @default.
- W1879944265 hasBestOaLocation W18799442651 @default.
- W1879944265 hasConcept C111133373 @default.
- W1879944265 hasConcept C141359234 @default.
- W1879944265 hasConcept C181199279 @default.
- W1879944265 hasConcept C185592680 @default.
- W1879944265 hasConcept C204999636 @default.
- W1879944265 hasConcept C2776970464 @default.
- W1879944265 hasConcept C4733338 @default.
- W1879944265 hasConcept C55493867 @default.
- W1879944265 hasConcept C73583747 @default.
- W1879944265 hasConceptScore W1879944265C111133373 @default.
- W1879944265 hasConceptScore W1879944265C141359234 @default.
- W1879944265 hasConceptScore W1879944265C181199279 @default.
- W1879944265 hasConceptScore W1879944265C185592680 @default.
- W1879944265 hasConceptScore W1879944265C204999636 @default.
- W1879944265 hasConceptScore W1879944265C2776970464 @default.
- W1879944265 hasConceptScore W1879944265C4733338 @default.
- W1879944265 hasConceptScore W1879944265C55493867 @default.
- W1879944265 hasConceptScore W1879944265C73583747 @default.
- W1879944265 hasIssue "2" @default.
- W1879944265 hasLocation W18799442651 @default.
- W1879944265 hasLocation W18799442652 @default.
- W1879944265 hasOpenAccess W1879944265 @default.
- W1879944265 hasPrimaryLocation W18799442651 @default.
- W1879944265 hasRelatedWork W1983309478 @default.
- W1879944265 hasRelatedWork W1998036938 @default.
- W1879944265 hasRelatedWork W2003189117 @default.
- W1879944265 hasRelatedWork W2053974957 @default.
- W1879944265 hasRelatedWork W2054450322 @default.
- W1879944265 hasRelatedWork W2066775909 @default.
- W1879944265 hasRelatedWork W2092690682 @default.
- W1879944265 hasRelatedWork W2393545005 @default.
- W1879944265 hasRelatedWork W2413585439 @default.
- W1879944265 hasRelatedWork W2886344725 @default.
- W1879944265 hasVolume "73" @default.
- W1879944265 isParatext "false" @default.
- W1879944265 isRetracted "false" @default.
- W1879944265 magId "1879944265" @default.