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- W1880092793 endingPage "57" @default.
- W1880092793 startingPage "45" @default.
- W1880092793 abstract "Peritoneal spread of tumors is a major problem in cancer management. Patients develop a marked deterioration in quality of life and shortened survival. This is in part due to bowel obstructions, marked ascites, and overall increase debilitation. Standard medical management has shown to be inadequate for the treatment of these problems. Surgery can palliate symptoms, however, it is unable to be complete at the microscopic level by a significant spillage of tumor cells throughout the abdomen. Chemotherapy can have some improvement in symptoms however it is short lived due to poor penetration into the peritoneal cavity. The role of intraperitoneal chemotherapy is to maximize tumor penetration and optimize cell death while minimizing systemic toxicity. Hyperthermic intraperitoneal chemotherapy (HIPEC) and early post-operative intraperitoneal chemotherapy (EPIC) are two treatment methods that serve this role and have been shown to improve survival. This review will discuss different chemotherapies used for both of these treatment options." @default.
- W1880092793 created "2016-06-24" @default.
- W1880092793 creator A5010369459 @default.
- W1880092793 creator A5028106795 @default.
- W1880092793 creator A5069610449 @default.
- W1880092793 creator A5070561439 @default.
- W1880092793 date "2016-02-01" @default.
- W1880092793 modified "2023-10-03" @default.
- W1880092793 title "Chemotherapy for intraperitoneal use: a review of hyperthermic intraperitoneal chemotherapy and early post-operative intraperitoneal chemotherapy." @default.
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