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- W1880409898 abstract "This chapter reviews cognitive and neuroimaging findings for each of the six anxiety disorders: obsessive‐compulsive disorder, posttraumatic stress disorder, panic disorder, specific phobia, social phobia, and generalized anxiety disorder. Cognitive biases toward threats are common to all six disorders and may correspond to hyperactivation of right hemisphere regions dedicated to threat. Brain structures subserving anxiety pathology include orbital frontal, prefrontal, anterior cingulate, and right parietal cortices, as well as the amygdala, hippocampus, and caudate. Neuropsychological data from extant research on cognitive, affective, and brain processes indicate that anxiety is not a homogenous entity and that attempts to map its neural circuitry must consider symptom variability and comorbidity with other types of psychopathology. This review of the neuroscience findings in anxiety disorders covers a wide array of methods that together provide knowledge of the brain mechanisms involved in the circuitry governing pathological forms of anxiety. The chapter discusses what is known about the neural circuitry of anxiety disorders by examining the relevant cognitive research and structural and functional neuroimaging data, including morphometric magnetic resonance imaging (MRI), functional MRI (f MRI), and positron emission tomography (PET). Various radiotracers are used such as [18F] fluorodeoxyglucose (FDG) for glucose metabolism and 15O‐labeled water for blood flow, single‐ photon emission computed tomography (SPECT) with 133Xenon or 99mTc‐ HMPAO, and scalp‐recorded electroencephalography (EEG)." @default.
- W1880409898 created "2016-06-24" @default.
- W1880409898 creator A5008740887 @default.
- W1880409898 creator A5086709175 @default.
- W1880409898 date "2005-01-01" @default.
- W1880409898 modified "2023-09-23" @default.
- W1880409898 title "Distinguishing Neural Substrates of Heterogeneity Among Anxiety Disorders" @default.
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