Matches in SemOpenAlex for { <https://semopenalex.org/work/W1880469068> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W1880469068 endingPage "3100" @default.
- W1880469068 startingPage "3094" @default.
- W1880469068 abstract "PURPOSE Patients with palpable extraprostatic disease (T3) have a poor prostate-specific antigen (PSA) failure-free (bNED) survival rate after radical prostatectomy (RP) or external-beam radiation therapy (RT). This study was performed to validate or refute the prognostic value of the previously defined calculated prostate cancer volume (cV(Ca)). PATIENTS AND METHODS For patients with clinically localized disease (T1c,2), a Cox regression multivariable analysis was used to assess the ability of the cV(Ca) value to predict time to posttherapy PSA failure following RP or RT. RESULTS The cV(Ca) value was a significant predictor (P < or = .0005) of time to posttherapy PSA failure in both an RP and RT data set independent of the one used to derive the cV(Ca)-based clinical staging system. In both RP- and RT-managed patients, estimates of 3-year bNED survival were not statistically different for patients with either T1c,2 disease and a cV(Ca) greater than 4.0 cm3 (RP, 27%; RT, 18%) or T3 disease (RP, 37%; RT, 34%). Despite pathologic T2 disease, the 3-year estimate of bNED survival was at most 51% in RP-managed patients with T1c,2 disease and cV(Ca) greater than 4.0 cm3. CONCLUSION A cV(Ca) greater than 4.0 cm3 identified patients with T1c.2 disease whose bNED survival was poor after RT or RP despite pathologic T2 disease that suggests the presence of occult micrometastatic disease in many of these patients. Prospective randomized trials to evaluate the impact on survival of adjuvant systemic therapy in these high-risk patients are justified." @default.
- W1880469068 created "2016-06-24" @default.
- W1880469068 creator A5005589801 @default.
- W1880469068 creator A5019239201 @default.
- W1880469068 creator A5023892217 @default.
- W1880469068 creator A5026425735 @default.
- W1880469068 creator A5028882558 @default.
- W1880469068 creator A5031239757 @default.
- W1880469068 creator A5035936938 @default.
- W1880469068 creator A5046274125 @default.
- W1880469068 creator A5068089995 @default.
- W1880469068 creator A5069654212 @default.
- W1880469068 creator A5078796303 @default.
- W1880469068 date "1998-09-01" @default.
- W1880469068 modified "2023-10-11" @default.
- W1880469068 title "Calculated prostate cancer volume greater than 4.0 cm3 identifies patients with localized prostate cancer who have a poor prognosis following radical prostatectomy or external-beam radiation therapy." @default.
- W1880469068 doi "https://doi.org/10.1200/jco.1998.16.9.3094" @default.
- W1880469068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9738580" @default.
- W1880469068 hasPublicationYear "1998" @default.
- W1880469068 type Work @default.
- W1880469068 sameAs 1880469068 @default.
- W1880469068 citedByCount "25" @default.
- W1880469068 countsByYear W18804690682012 @default.
- W1880469068 countsByYear W18804690682013 @default.
- W1880469068 countsByYear W18804690682014 @default.
- W1880469068 countsByYear W18804690682015 @default.
- W1880469068 countsByYear W18804690682022 @default.
- W1880469068 crossrefType "journal-article" @default.
- W1880469068 hasAuthorship W1880469068A5005589801 @default.
- W1880469068 hasAuthorship W1880469068A5019239201 @default.
- W1880469068 hasAuthorship W1880469068A5023892217 @default.
- W1880469068 hasAuthorship W1880469068A5026425735 @default.
- W1880469068 hasAuthorship W1880469068A5028882558 @default.
- W1880469068 hasAuthorship W1880469068A5031239757 @default.
- W1880469068 hasAuthorship W1880469068A5035936938 @default.
- W1880469068 hasAuthorship W1880469068A5046274125 @default.
- W1880469068 hasAuthorship W1880469068A5068089995 @default.
- W1880469068 hasAuthorship W1880469068A5069654212 @default.
- W1880469068 hasAuthorship W1880469068A5078796303 @default.
- W1880469068 hasConcept C121608353 @default.
- W1880469068 hasConcept C126322002 @default.
- W1880469068 hasConcept C126894567 @default.
- W1880469068 hasConcept C141071460 @default.
- W1880469068 hasConcept C143998085 @default.
- W1880469068 hasConcept C188816634 @default.
- W1880469068 hasConcept C2775908122 @default.
- W1880469068 hasConcept C2776235491 @default.
- W1880469068 hasConcept C2778162587 @default.
- W1880469068 hasConcept C2779466945 @default.
- W1880469068 hasConcept C2780192828 @default.
- W1880469068 hasConcept C2781406297 @default.
- W1880469068 hasConcept C50382708 @default.
- W1880469068 hasConcept C509974204 @default.
- W1880469068 hasConcept C71924100 @default.
- W1880469068 hasConceptScore W1880469068C121608353 @default.
- W1880469068 hasConceptScore W1880469068C126322002 @default.
- W1880469068 hasConceptScore W1880469068C126894567 @default.
- W1880469068 hasConceptScore W1880469068C141071460 @default.
- W1880469068 hasConceptScore W1880469068C143998085 @default.
- W1880469068 hasConceptScore W1880469068C188816634 @default.
- W1880469068 hasConceptScore W1880469068C2775908122 @default.
- W1880469068 hasConceptScore W1880469068C2776235491 @default.
- W1880469068 hasConceptScore W1880469068C2778162587 @default.
- W1880469068 hasConceptScore W1880469068C2779466945 @default.
- W1880469068 hasConceptScore W1880469068C2780192828 @default.
- W1880469068 hasConceptScore W1880469068C2781406297 @default.
- W1880469068 hasConceptScore W1880469068C50382708 @default.
- W1880469068 hasConceptScore W1880469068C509974204 @default.
- W1880469068 hasConceptScore W1880469068C71924100 @default.
- W1880469068 hasIssue "9" @default.
- W1880469068 hasLocation W18804690681 @default.
- W1880469068 hasLocation W18804690682 @default.
- W1880469068 hasOpenAccess W1880469068 @default.
- W1880469068 hasPrimaryLocation W18804690681 @default.
- W1880469068 hasRelatedWork W1888477076 @default.
- W1880469068 hasRelatedWork W2032157250 @default.
- W1880469068 hasRelatedWork W2418143924 @default.
- W1880469068 hasRelatedWork W2777583152 @default.
- W1880469068 hasRelatedWork W2957009455 @default.
- W1880469068 hasRelatedWork W4230379269 @default.
- W1880469068 hasRelatedWork W4255881101 @default.
- W1880469068 hasRelatedWork W42639213 @default.
- W1880469068 hasRelatedWork W4321059387 @default.
- W1880469068 hasRelatedWork W2023475404 @default.
- W1880469068 hasVolume "16" @default.
- W1880469068 isParatext "false" @default.
- W1880469068 isRetracted "false" @default.
- W1880469068 magId "1880469068" @default.
- W1880469068 workType "article" @default.