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- W188049268 abstract "Cellular hypersensitivity (cell-mediated immunity) is an immunologic reaction that is dependent upon the activity of sensitized lymphocytes rather than specific immunoglobulin. In most cases the lymphocytes do not act directly as effectors, but elaborate soluble products which are known as lymphokines. The classic example of a cell-mediated immune reaction is that of “delayed hypersensitivity,” which is the cutaneous manifestation of this form of response. It is also referred to, especially in the older literature, as “tuberculin” type hypersensitivity. The delayed reaction is a slowly evolving inflammatory reaction (24–48 h to reach maximal size) which develops at the site of injection of antigen into a previously sensitized individual. It appears grossly as an indurated lump and microscopically, at least in man and the guinea pig, as a collection of lymphocytes and macrophages which are usually collectively referred to as “mononuclear” cells. The delayed hypersensitivity reaction can be transferred to a normal, nonimmune individual by sensitized lymphocytes, but not by serum." @default.
- W188049268 created "2016-06-24" @default.
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- W188049268 date "1979-01-01" @default.
- W188049268 modified "2023-09-26" @default.
- W188049268 title "Cellular Hypersensitivity and Inflammation" @default.
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- W188049268 doi "https://doi.org/10.1007/978-3-642-67311-5_9" @default.
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