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- W1880666418 abstract "A phytochemical study of dart and arrow poison from the Matis tribe led to the identification of D-(-)-quinic acid, L-malic acid, ethyldimethylamine, magnoflorine, and five new bisbenzyltetrahydroisoquinoline alkaloids (BBIQAs), 1-5. D-Tubocurarine could not be identified among these products. BBIQA (3) contains a unique linkage at C-8 and C-11'. All structures were characterized by a combination of NMR and HRESIMS data. The effects of Matis poison and individual BBIQAs (1-3) on rat muscle nAChR expressed in Xenopus oocytes have been investigated using the two-electrode voltage clamp technique." @default.
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- W1880666418 date "2015-10-23" @default.
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- W1880666418 title "Curare Alkaloids: Constituents of a Matis Dart Poison" @default.
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- W1880666418 doi "https://doi.org/10.1021/acs.jnatprod.5b00457" @default.
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