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- W1880816091 abstract "The challenge posed to the health sector by the use of catheter is as synonymous to its importance. Catheters encouragebiofilm formation leading to bacteriuria, cystitis, urethritis, pyelonephritis and death in severe cases. This study was aimedat the prevention of E. coli biofilm formation using methanolic extracts of 3 different plants, Psidium guajava, Mangifera indicaand Ocimum gratissimum. Plant extractions were carried using the solvent methanol via cold extraction. Varying concentrationsof the extracts were prepared (5.0, 10.0 and 20.0 mg/mL) and used to coat 63 catheters using mild heat from water bath. Biofilmformation was analyzed using aerobic plate count and Optical density (OD600) count. From the results obtained Psidium guajava,Mangifera indica and Ocimum gratissimum were not able to prevent the growth E. coli species but delayed the onset of biofilmformation for about a week. Ocimum gratissium had the highest inhibitory effect at 5.0 mg/mL, 10.0 mg/L and 20.0 mg/mL withcolony forming unit ranging from (2.2×105 -7.0×104 and 5.7×105- 3.7×105) for day 5 and 7 analysis respectively. Psidium guajavahad the lowest inhibitory effect at these concentrations, with colony forming unit ranging from (4.3×105-1.9×103 and 7.7×105-3.8×105) for day 5 and 7 analysis respectively. Although the three extracts varied in their antimicrobial capacity, the differenceshowever, were statistically not significant. Psidium guajava, Mangifera indica and Ocimum gratissimum still remains a good choiceagainst several pathogenic organisms and in ethnomedicine but can only be used for short term catheterization" @default.
- W1880816091 created "2016-06-24" @default.
- W1880816091 creator A5060776276 @default.
- W1880816091 date "2013-09-01" @default.
- W1880816091 modified "2023-09-27" @default.
- W1880816091 title "Prevention of Escherichia coli biofilms Formation on Urinary Catheter by some Selected PlantExtracts" @default.
- W1880816091 hasPublicationYear "2013" @default.
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