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- W188090560 endingPage "362" @default.
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- W188090560 abstract "Gonadotropin dependant precocious puberty is a heterogeneous disease with variable clinical presentations ranging from incomplete forms of precocious pubertal development to rapidly progressive forms. Although there is some controversy about the indications for treatment of central precocious puberty, in this chapter we review and clarify the indications as well as summarize the various methods available for monitoring therapy. Gonadotropin releasing hormone agonists (GnRHa) are currently considered the treatment of choice for central precocious puberty (CPP). Long-term outcome studies have shown that GnRHa have completely reversible suppressive effects on the hypothalamic-pituitary-gonadal axis, preserve final adult height, and have no long-term effects on bone mineral density and body composition in children with CPP. Newer therapies for use in CPP such as GnRH antagonists and third generation aromatase inhibitors are currently being studied and may be additional treatment options in the future" @default.
- W188090560 created "2016-06-24" @default.
- W188090560 creator A5039488789 @default.
- W188090560 creator A5046580611 @default.
- W188090560 date "2007-01-01" @default.
- W188090560 modified "2023-10-11" @default.
- W188090560 title "Treatment of Gonadotropin-Dependent Precocious Puberty" @default.
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- W188090560 doi "https://doi.org/10.1007/978-1-59745-499-5_16" @default.
- W188090560 hasPublicationYear "2007" @default.
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