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- W1881752912 endingPage "2248" @default.
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- W1881752912 abstract "Lipopolysaccharide isolated from Pseudomonas aeruginosa PAO1 (O5 serotype) was separated into two antigenically distinct fractions. A minor fraction, containing shorter polysaccharide chains, reacted with a monoclonal antibody to a P. aeruginosa common antigen but did not react with antibodies specific to O5-serotype lipopolysaccharide. In contrast, fractions containing long polysaccharide chains reacted only with the O5-specific monoclonal antibodies. The shorter, common-antigen fraction lacked phosphate and contained stoichiometric amounts of sulfate, and the fatty acid composition of this fraction was similar to that of the O-antigen-specific fraction. The lipid A derived from the serotype-specific lipopolysaccharide cross-reacted with monoclonal antibodies against lipid A from Escherichia coli, while the lipid A derived from the common antigen did not react. We propose that many serotypes of P. aeruginosa produce two chemically and antigenically distinct lipopolysaccharide molecules, one of which is a common antigen with a short polysaccharide and a unique core-lipid A structure." @default.
- W1881752912 created "2016-06-24" @default.
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- W1881752912 date "1989-04-01" @default.
- W1881752912 modified "2023-09-30" @default.
- W1881752912 title "Analysis of a common-antigen lipopolysaccharide from Pseudomonas aeruginosa" @default.
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- W1881752912 doi "https://doi.org/10.1128/jb.171.4.2244-2248.1989" @default.
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