Matches in SemOpenAlex for { <https://semopenalex.org/work/W188235598> ?p ?o ?g. }
- W188235598 abstract "Prostate cancer responds dramatically to androgen ablative therapy. For the majority of patients, the responses are not durable, particularly in bone, and progression developed in a median of 12–18 months [1,2]. Once hormone-refractory disease becomes clinically manifest, no standard therapy exists [3], and median survival rarely exceeds one year. While the exact etiology of androgen independence is not well defined, increasing evidence suggests that autocrine and paracrine production of specific growth factors may be contributory [4]. The unique avidity of prostatic cancer cells for the skeleton, a cause of significant morbidity [5], is also partially related to the presence of specific bone marrow derived growth factors that stimulate prostatic cancer cell growth [6]. This report describes therapies directed specifically to prostatic cancer in the skeleton and to one putative growth factor inhibitor, suramin, that has recently shown activity in the hormone refractory setting." @default.
- W188235598 created "2016-06-24" @default.
- W188235598 creator A5015396908 @default.
- W188235598 creator A5018167887 @default.
- W188235598 creator A5058359283 @default.
- W188235598 creator A5070062710 @default.
- W188235598 creator A5071888093 @default.
- W188235598 creator A5072850546 @default.
- W188235598 date "1992-01-01" @default.
- W188235598 modified "2023-10-16" @default.
- W188235598 title "Hormone Refractory Prostatic Cancer: The Role of Radiolabelled Diphosphonates and Growth Factor Inhibitors" @default.
- W188235598 cites W103322254 @default.
- W188235598 cites W1797512951 @default.
- W188235598 cites W1927196455 @default.
- W188235598 cites W1967642037 @default.
- W188235598 cites W1972757089 @default.
- W188235598 cites W1979269481 @default.
- W188235598 cites W1980756505 @default.
- W188235598 cites W1999578603 @default.
- W188235598 cites W2005709557 @default.
- W188235598 cites W2005808983 @default.
- W188235598 cites W2008736019 @default.
- W188235598 cites W2016194308 @default.
- W188235598 cites W2018996258 @default.
- W188235598 cites W2021504540 @default.
- W188235598 cites W2038736289 @default.
- W188235598 cites W2052425221 @default.
- W188235598 cites W2052524715 @default.
- W188235598 cites W2053356196 @default.
- W188235598 cites W2054577494 @default.
- W188235598 cites W2055869196 @default.
- W188235598 cites W2059342531 @default.
- W188235598 cites W2060401436 @default.
- W188235598 cites W2077148233 @default.
- W188235598 cites W2087339481 @default.
- W188235598 cites W2087432461 @default.
- W188235598 cites W2092351058 @default.
- W188235598 cites W2103227635 @default.
- W188235598 cites W2108739789 @default.
- W188235598 cites W2111161686 @default.
- W188235598 cites W2153189056 @default.
- W188235598 cites W2154652969 @default.
- W188235598 cites W2155510257 @default.
- W188235598 cites W2161654899 @default.
- W188235598 cites W2196881671 @default.
- W188235598 cites W2242063705 @default.
- W188235598 cites W2271098438 @default.
- W188235598 cites W2397424273 @default.
- W188235598 cites W2411644748 @default.
- W188235598 cites W2467309903 @default.
- W188235598 cites W2471857435 @default.
- W188235598 cites W27570217 @default.
- W188235598 cites W4233268218 @default.
- W188235598 cites W4241178025 @default.
- W188235598 cites W4246838396 @default.
- W188235598 doi "https://doi.org/10.1007/978-1-4615-3398-6_12" @default.
- W188235598 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1283494" @default.
- W188235598 hasPublicationYear "1992" @default.
- W188235598 type Work @default.
- W188235598 sameAs 188235598 @default.
- W188235598 citedByCount "0" @default.
- W188235598 crossrefType "book-chapter" @default.
- W188235598 hasAuthorship W188235598A5015396908 @default.
- W188235598 hasAuthorship W188235598A5018167887 @default.
- W188235598 hasAuthorship W188235598A5058359283 @default.
- W188235598 hasAuthorship W188235598A5070062710 @default.
- W188235598 hasAuthorship W188235598A5071888093 @default.
- W188235598 hasAuthorship W188235598A5072850546 @default.
- W188235598 hasConcept C121608353 @default.
- W188235598 hasConcept C126322002 @default.
- W188235598 hasConcept C128240485 @default.
- W188235598 hasConcept C134018914 @default.
- W188235598 hasConcept C142424586 @default.
- W188235598 hasConcept C143998085 @default.
- W188235598 hasConcept C170493617 @default.
- W188235598 hasConcept C2780192828 @default.
- W188235598 hasConcept C502942594 @default.
- W188235598 hasConcept C71924100 @default.
- W188235598 hasConcept C7876069 @default.
- W188235598 hasConcept C86803240 @default.
- W188235598 hasConcept C87355193 @default.
- W188235598 hasConceptScore W188235598C121608353 @default.
- W188235598 hasConceptScore W188235598C126322002 @default.
- W188235598 hasConceptScore W188235598C128240485 @default.
- W188235598 hasConceptScore W188235598C134018914 @default.
- W188235598 hasConceptScore W188235598C142424586 @default.
- W188235598 hasConceptScore W188235598C143998085 @default.
- W188235598 hasConceptScore W188235598C170493617 @default.
- W188235598 hasConceptScore W188235598C2780192828 @default.
- W188235598 hasConceptScore W188235598C502942594 @default.
- W188235598 hasConceptScore W188235598C71924100 @default.
- W188235598 hasConceptScore W188235598C7876069 @default.
- W188235598 hasConceptScore W188235598C86803240 @default.
- W188235598 hasConceptScore W188235598C87355193 @default.
- W188235598 hasLocation W1882355981 @default.
- W188235598 hasLocation W1882355982 @default.
- W188235598 hasOpenAccess W188235598 @default.
- W188235598 hasPrimaryLocation W1882355981 @default.
- W188235598 hasRelatedWork W1966504330 @default.
- W188235598 hasRelatedWork W1979139803 @default.