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• W1882698603 abstract "Introdução: A tuberculose (TB) é uma importante causa de mortalidade e morbilidade mundial. Em Portugal, na última década do século xx, assistiu-se a uma diminuição da incidência de TB no grupo etário com menos de 15 anos. Material e métodos: Análise retrospectiva dos casos de TB doença em crianças internadas no Centro Hospitalar de Vila Nova de Gaia entre 1 de Janeiro de 2000 e 31 de Dezembro de 2007. Analisaram-se os respectivos dados epidemiológicos, clínicos, radioló-gicos, microbiológicos e terapêuticos. Resultados: No período estudado registaram-se 23 casos de tuberculose doença (78% TB pulmonar e 22% TB extrapulmonar). A faixa etária variou dos 6 meses aos 16 anos, predominando o sexo masculino. Todos os doentes tinham sido previamente vacinados com BCG e existia história de contacto prévio com TB em 57%. O ano de 2007 foi aquele em que ocor-reu um maior número de casos. A prova de Mantoux foi positiva em 91% dos casos e o isolamento de M. tuberculosis foi possível em 61%. A colheita de suco gástrico permitiu o isolamento em 1/3 dos casos e a broncoscopia contribuiu para o isolamento do M. tuberculosis em 43% dos casos com suco gástrico negativo. Todos os doentes efectuaram, no mínimo, 6 meses de tratamento com antibacilares, não sendo documen-tadas resistências. Após internamento, identificaram-se 43% (n = 10) casos intrafamiliares de TB. Conclusão: A tuberculose mantém-se um problema actual, sendo o diagnóstico, o rastreio dos contactos e o cumprimento terapêutico (inclusive profiláctico) um desafio fulcral na sua contenção. Rev Port Pneumol 2009; XV (5): 771-782 Introduction: Tuberculosis is a leading cause of world-wide mortality and morbidity. A reduced rate of tuberculosis in people aged less than 15 years has been seen in Portugal over the last decade of the twentieth century. Material and methods: Retrospective analysis of tuberculosis cases in children admitted to the Centro Hospitalar de Vila Nova de Gaia January 1 2000 to December 31 2007. The individual epidemiological, clinical, radiological, microbiological and treatment information was analysed. Results: We found 23 cases of tuberculosis disease (78% pulmonary tuberculosis and 22% extra-pulmonary tuberculosis). Children’s ages varied from 6 months to 16 years, with the male gender predo-minant. All patients had previously been vaccinated with BCG and there was a prior contact with TB in 57%. 2007 was the year with the highest number of cases. The Mantoux test was positive in 91% cases and M. tuberculosis isolation was possible in 61%. Gastric fluid analysis allowed isolation in 1/3 of cases and bronchoscopy contributed to M. tuberculosis isolation in 43% cases with negative gastric fluid analysis. Every patient underwent at least 6 months of tuberculostatic treatment, without any documented resistances. Conclusion: Tuberculosis remains a real problem, with the diagnosis, the search for contacts and adequate treatment (including prophylaxis) the main challenge. Rev Port Pneumol 2009; XV (5): 771-782" @default.
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• W1882698603 date "2009-09-01" @default.
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• W1882698603 title "Tuberculose doença – Casuística de um serviço de pediatria no século XXI" @default.
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• W1882698603 doi "https://doi.org/10.1016/s0873-2159(15)30178-1" @default.
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