FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1885423539> ?p ?o ?g. }

• W1885423539 endingPage "1883" @default.
• W1885423539 startingPage "1875" @default.
• W1885423539 abstract "Because radioactive precursors can be injected directly into the cell body or axon of R2, a giant, identified neuron of the Aplysia abdominal ganglion, it was possible to show that glycolipid is synthesized in the cell body, inserted into membranes along with glycoprotein, and then exported into the axon within organelles that are moved by fast axonal transport. After intrasomatic injection of N-[3H]-acetyl-D-galactosamine, five major 3H-glycolipids were identified using thin layer polysilicic acid glass fiber chromatography. At least two of the lipids are negatively charged. Analysis of 32P-labeled lipid from the abdominal ganglion revealed the presence of 2-aminoethylphosphonate, indicating that these polar substances are sphingophosphonoglycolipids. The major 3H-glycolipids synthesized in R2 are similar to a family of phospholipids isolated from the skin of A. kurodai, previously characterized by Araki et al. (Araki, S., Y. Komai, and M. Satake (1980) Biochem J. 87: 503-510). Since sialic acid is absent in Aplysia as in other invertebrates, these polar glycolipids may function like gangliosides in vertebrates. The polar 3H-glycolipids are synthesized and incorporated into intracytoplasmic membranes solely in the cell body. Direct injection of the labeled sugar into the axon revealed no local synthesis or exchange of glycolipid. Moreover, there was no indication for transfer from glial cells into axoplasm. Although the incorporation of N-[3H]-acetyl-D-galactosamine into glycolipid is not affected by anisomycin, an effective inhibitor of protein synthesis, the export into the axon of membranes containing the newly synthesized lipid is completely blocked by the drug.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W1885423539 created "2016-06-24" @default.
• W1885423539 creator A5007323247 @default.
• W1885423539 creator A5027636296 @default.
• W1885423539 creator A5048771352 @default.
• W1885423539 date "1984-07-01" @default.
• W1885423539 modified "2023-10-16" @default.
• W1885423539 title "Characterization of glycolipids synthesized in an identified neuron of Aplysia californica" @default.
• W1885423539 cites W1511810439 @default.
• W1885423539 cites W1529038768 @default.
• W1885423539 cites W1530115708 @default.
• W1885423539 cites W1918646363 @default.
• W1885423539 cites W1927707188 @default.
• W1885423539 cites W1970897261 @default.
• W1885423539 cites W1972706960 @default.
• W1885423539 cites W1973063119 @default.
• W1885423539 cites W1980033934 @default.
• W1885423539 cites W1998894167 @default.
• W1885423539 cites W2004936345 @default.
• W1885423539 cites W2011138734 @default.
• W1885423539 cites W2033322630 @default.
• W1885423539 cites W2039586277 @default.
• W1885423539 cites W2042941364 @default.
• W1885423539 cites W2055695762 @default.
• W1885423539 cites W2055982868 @default.
• W1885423539 cites W2070439727 @default.
• W1885423539 cites W2077275898 @default.
• W1885423539 cites W2077813577 @default.
• W1885423539 cites W2083385398 @default.
• W1885423539 cites W2086288913 @default.
• W1885423539 cites W2087679079 @default.
• W1885423539 cites W2095549072 @default.
• W1885423539 cites W2097775506 @default.
• W1885423539 cites W2112817302 @default.
• W1885423539 cites W2122089332 @default.
• W1885423539 cites W2143651487 @default.
• W1885423539 cites W2162763750 @default.
• W1885423539 cites W2178057437 @default.
• W1885423539 cites W2217609893 @default.
• W1885423539 cites W2405341196 @default.
• W1885423539 cites W2414057266 @default.
• W1885423539 cites W2439242760 @default.
• W1885423539 cites W99433102 @default.
• W1885423539 doi "https://doi.org/10.1523/jneurosci.04-07-01875.1984" @default.
• W1885423539 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6564885" @default.
• W1885423539 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6204024" @default.
• W1885423539 hasPublicationYear "1984" @default.
• W1885423539 type Work @default.
• W1885423539 sameAs 1885423539 @default.
• W1885423539 citedByCount "8" @default.
• W1885423539 countsByYear W18854235392012 @default.
• W1885423539 crossrefType "journal-article" @default.
• W1885423539 hasAuthorship W1885423539A5007323247 @default.
• W1885423539 hasAuthorship W1885423539A5027636296 @default.
• W1885423539 hasAuthorship W1885423539A5048771352 @default.
• W1885423539 hasBestOaLocation W18854235391 @default.
• W1885423539 hasConcept C12554922 @default.
• W1885423539 hasConcept C168240541 @default.
• W1885423539 hasConcept C169760540 @default.
• W1885423539 hasConcept C185592680 @default.
• W1885423539 hasConcept C22222904 @default.
• W1885423539 hasConcept C2778178740 @default.
• W1885423539 hasConcept C2779530196 @default.
• W1885423539 hasConcept C41625074 @default.
• W1885423539 hasConcept C55493867 @default.
• W1885423539 hasConcept C86803240 @default.
• W1885423539 hasConcept C95444343 @default.
• W1885423539 hasConceptScore W1885423539C12554922 @default.
• W1885423539 hasConceptScore W1885423539C168240541 @default.
• W1885423539 hasConceptScore W1885423539C169760540 @default.
• W1885423539 hasConceptScore W1885423539C185592680 @default.
• W1885423539 hasConceptScore W1885423539C22222904 @default.
• W1885423539 hasConceptScore W1885423539C2778178740 @default.
• W1885423539 hasConceptScore W1885423539C2779530196 @default.
• W1885423539 hasConceptScore W1885423539C41625074 @default.
• W1885423539 hasConceptScore W1885423539C55493867 @default.
• W1885423539 hasConceptScore W1885423539C86803240 @default.
• W1885423539 hasConceptScore W1885423539C95444343 @default.
• W1885423539 hasIssue "7" @default.
• W1885423539 hasLocation W18854235391 @default.
• W1885423539 hasLocation W18854235392 @default.
• W1885423539 hasLocation W18854235393 @default.
• W1885423539 hasLocation W18854235394 @default.
• W1885423539 hasOpenAccess W1885423539 @default.
• W1885423539 hasPrimaryLocation W18854235391 @default.
• W1885423539 hasRelatedWork W1968833258 @default.
• W1885423539 hasRelatedWork W2000060717 @default.
• W1885423539 hasRelatedWork W2039586277 @default.
• W1885423539 hasRelatedWork W2069561992 @default.
• W1885423539 hasRelatedWork W2071424178 @default.
• W1885423539 hasRelatedWork W2077275898 @default.
• W1885423539 hasRelatedWork W2314483475 @default.
• W1885423539 hasRelatedWork W3034230502 @default.
• W1885423539 hasRelatedWork W3184746592 @default.
• W1885423539 hasRelatedWork W4255519781 @default.
• W1885423539 hasVolume "4" @default.
• W1885423539 isParatext "false" @default.
• W1885423539 isRetracted "false" @default.

• next