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- W1885453944 startingPage "2659" @default.
- W1885453944 abstract "Abstract Since the original proposal by Fearon and Locksley (Fearon and Locksley. 1996. Science 272: 50–53) that the complement system linked innate and adaptive immunity, there has been a rapid expansion of studies on this topic. With the advance of intravital imaging, a number of recent papers revealed an additional novel pathway in which complement C3 and its receptors enhance humoral immunity through delivery of Ag to the B cell compartment. In this review, we discuss this pathway and highlight several novel exceptions recently found with a model influenza vaccine, such as mannose-binding lectin opsonization of influenza and uptake by macrophages, and the capture of virus by dendritic cells residing in the medullary compartment of peripheral lymph nodes." @default.
- W1885453944 created "2016-06-24" @default.
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- W1885453944 date "2010-09-01" @default.
- W1885453944 modified "2023-09-25" @default.
- W1885453944 title "Complement-Dependent Transport of Antigen into B Cell Follicles" @default.
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- W1885453944 doi "https://doi.org/10.4049/jimmunol.1000522" @default.
- W1885453944 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3477863" @default.
- W1885453944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20724732" @default.
- W1885453944 hasPublicationYear "2010" @default.
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