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• W1885493605 endingPage "846" @default.
• W1885493605 startingPage "829" @default.
• W1885493605 abstract "Oocyte nuclear proteins of Xenopus are distributed into the cytoplasm of the maturing egg after germinal vesicle breakdown. Later they are found in all cell nuclei of the embryo. At early stages of development, different nuclear proteins behave differently. A class of 'early shifting' antigens is accumulated by pronuclei and cleavage nuclei, whereas others appear to be excluded from the nuclei at early stages but are shifted into the nuclei at blastula or during and after gastrulation. Accumulation of 'late-shifting' nuclear antigens is a gradual process and occurs during a period characteristic of each protein. Multiple artificial pronuclei can be formed after injection of sperm nuclei, erythrocyte nuclei or pure lambda-DNA into unfertilized eggs. The artificial pronuclei accumulate early- but not late-shifting proteins. Early-migrating proteins rapidly accumulate into the germinal vesicle after de novo synthesis in the oocyte, indicating that the efficiency of translocation into nuclei is an intrinsic property of each protein. Artificial extension of the length of the cell cycle before midblastula transition does not lead to accumulation of the late-shifting nuclear antigens investigated." @default.
• W1885493605 created "2016-06-24" @default.
• W1885493605 creator A5087866745 @default.
• W1885493605 date "1987-12-01" @default.
• W1885493605 modified "2023-10-04" @default.
• W1885493605 title "Differential accumulation of oocyte nuclear proteins by embryonic nuclei of <i>Xenopus</i>" @default.
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• W1885493605 doi "https://doi.org/10.1242/dev.101.4.829" @default.
• W1885493605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3332618" @default.
• W1885493605 hasPublicationYear "1987" @default.
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