Matches in SemOpenAlex for { <https://semopenalex.org/work/W1886572344> ?p ?o ?g. }
- W1886572344 abstract "Infants with birth asphyxia frequently require resuscitation. Current guidance is to start newborn resuscitation in 21% oxygen. However, infants with severe hypoxia-ischaemia may require prolonged resuscitation with oxygen. To date, no study has looked at the effect of resuscitation in 100% oxygen following a severe hypoxic-ischaemic insult.Postnatal day 7 Wistar rats underwent a severe hypoxic-ischaemic insult (modified Vannucci unilateral brain injury model) followed by immediate resuscitation in either 21% or 100% oxygen for 30 min. Seven days following the insult, negative geotaxis testing was performed in survivors, and the brains were harvested. Relative ipsilateral cortical and hippocampal area loss was assessed histologically.Total area loss in the affected hemisphere and area loss within the hippocampus did not significantly differ between the two groups. The same results were seen for short-term neurological assessment. No difference was seen in weight gain between pups resuscitated in 21% and 100% oxygen.Resuscitation in 100% oxygen does not cause a deleterious effect on brain injury following a severe hypoxic-ischaemic insult in a rat model of hypoxia-ischaemia. Further work investigating the effects of resuscitation in 100% oxygen is warranted, especially for newborn infants with severe hypoxic-ischaemic encephalopathy." @default.
- W1886572344 created "2016-06-24" @default.
- W1886572344 creator A5015337633 @default.
- W1886572344 creator A5023263519 @default.
- W1886572344 creator A5024329074 @default.
- W1886572344 creator A5024498709 @default.
- W1886572344 creator A5053438521 @default.
- W1886572344 creator A5075041400 @default.
- W1886572344 date "2015-11-01" @default.
- W1886572344 modified "2023-09-27" @default.
- W1886572344 title "The effect of resuscitation in 100% oxygen on brain injury in a newborn rat model of severe hypoxic-ischaemic encephalopathy" @default.
- W1886572344 cites W1543691530 @default.
- W1886572344 cites W1963531783 @default.
- W1886572344 cites W1970861924 @default.
- W1886572344 cites W1978708942 @default.
- W1886572344 cites W1984391795 @default.
- W1886572344 cites W1986118588 @default.
- W1886572344 cites W1986673001 @default.
- W1886572344 cites W1991122679 @default.
- W1886572344 cites W1993510527 @default.
- W1886572344 cites W1997441377 @default.
- W1886572344 cites W2001116239 @default.
- W1886572344 cites W2004730509 @default.
- W1886572344 cites W2006654108 @default.
- W1886572344 cites W2016619395 @default.
- W1886572344 cites W2017606109 @default.
- W1886572344 cites W2022755804 @default.
- W1886572344 cites W2024644391 @default.
- W1886572344 cites W2027917639 @default.
- W1886572344 cites W2046702675 @default.
- W1886572344 cites W2055855125 @default.
- W1886572344 cites W2058904157 @default.
- W1886572344 cites W2065395481 @default.
- W1886572344 cites W2079136352 @default.
- W1886572344 cites W2080355701 @default.
- W1886572344 cites W2082469825 @default.
- W1886572344 cites W2087928302 @default.
- W1886572344 cites W2093577835 @default.
- W1886572344 cites W2095517106 @default.
- W1886572344 cites W2099448554 @default.
- W1886572344 cites W2100382017 @default.
- W1886572344 cites W2111189180 @default.
- W1886572344 cites W2111928410 @default.
- W1886572344 cites W2129856224 @default.
- W1886572344 cites W2132866920 @default.
- W1886572344 cites W2136967026 @default.
- W1886572344 cites W2150608467 @default.
- W1886572344 cites W2155508486 @default.
- W1886572344 cites W2169982975 @default.
- W1886572344 cites W2615154296 @default.
- W1886572344 doi "https://doi.org/10.1016/j.resuscitation.2015.07.050" @default.
- W1886572344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26300234" @default.
- W1886572344 hasPublicationYear "2015" @default.
- W1886572344 type Work @default.
- W1886572344 sameAs 1886572344 @default.
- W1886572344 citedByCount "6" @default.
- W1886572344 countsByYear W18865723442016 @default.
- W1886572344 countsByYear W18865723442017 @default.
- W1886572344 countsByYear W18865723442019 @default.
- W1886572344 countsByYear W18865723442020 @default.
- W1886572344 crossrefType "journal-article" @default.
- W1886572344 hasAuthorship W1886572344A5015337633 @default.
- W1886572344 hasAuthorship W1886572344A5023263519 @default.
- W1886572344 hasAuthorship W1886572344A5024329074 @default.
- W1886572344 hasAuthorship W1886572344A5024498709 @default.
- W1886572344 hasAuthorship W1886572344A5053438521 @default.
- W1886572344 hasAuthorship W1886572344A5075041400 @default.
- W1886572344 hasBestOaLocation W18865723442 @default.
- W1886572344 hasConcept C126322002 @default.
- W1886572344 hasConcept C178790620 @default.
- W1886572344 hasConcept C185592680 @default.
- W1886572344 hasConcept C2778165595 @default.
- W1886572344 hasConcept C2778621155 @default.
- W1886572344 hasConcept C2779914510 @default.
- W1886572344 hasConcept C2780164069 @default.
- W1886572344 hasConcept C2781458332 @default.
- W1886572344 hasConcept C2909832856 @default.
- W1886572344 hasConcept C42219234 @default.
- W1886572344 hasConcept C540031477 @default.
- W1886572344 hasConcept C541997718 @default.
- W1886572344 hasConcept C71924100 @default.
- W1886572344 hasConcept C7836513 @default.
- W1886572344 hasConceptScore W1886572344C126322002 @default.
- W1886572344 hasConceptScore W1886572344C178790620 @default.
- W1886572344 hasConceptScore W1886572344C185592680 @default.
- W1886572344 hasConceptScore W1886572344C2778165595 @default.
- W1886572344 hasConceptScore W1886572344C2778621155 @default.
- W1886572344 hasConceptScore W1886572344C2779914510 @default.
- W1886572344 hasConceptScore W1886572344C2780164069 @default.
- W1886572344 hasConceptScore W1886572344C2781458332 @default.
- W1886572344 hasConceptScore W1886572344C2909832856 @default.
- W1886572344 hasConceptScore W1886572344C42219234 @default.
- W1886572344 hasConceptScore W1886572344C540031477 @default.
- W1886572344 hasConceptScore W1886572344C541997718 @default.
- W1886572344 hasConceptScore W1886572344C71924100 @default.
- W1886572344 hasConceptScore W1886572344C7836513 @default.
- W1886572344 hasLocation W18865723441 @default.
- W1886572344 hasLocation W18865723442 @default.
- W1886572344 hasLocation W18865723443 @default.
- W1886572344 hasLocation W18865723444 @default.