Matches in SemOpenAlex for { <https://semopenalex.org/work/W1887118332> ?p ?o ?g. }
- W1887118332 endingPage "16539" @default.
- W1887118332 startingPage "16524" @default.
- W1887118332 abstract "Mitochondria are involved in the aging processes that ultimately lead to neurodegeneration and the development of Alzheimer's disease (AD). A healthy lifestyle, including a diet rich in antioxidants and polyphenols, represents one strategy to protect the brain and to prevent neurodegeneration. We recently reported that a stabilized hexanic rice bran extract (RBE) rich in vitamin E and polyphenols (but unsuitable for human consumption) has beneficial effects on mitochondrial function in vitro and in vivo (doi:10.1016/j.phrs.2013.06.008, 10.3233/JAD-132084). To enable the use of RBE as food additive, a stabilized ethanolic extract has been produced. Here, we compare the vitamin E profiles of both extracts and their effects on mitochondrial function (ATP concentrations, mitochondrial membrane potential, mitochondrial respiration and mitochondrial biogenesis) in PC12 cells. We found that vitamin E contents and the effects of both RBE on mitochondrial function were similar. Furthermore, we aimed to identify components responsible for the mitochondria-protective effects of RBE, but could not achieve a conclusive result. α-Tocotrienol and possibly also γ-tocotrienol, α-tocopherol and δ-tocopherol might be involved, but hitherto unknown components of RBE or a synergistic effect of various components might also play a role in mediating RBE's beneficial effects on mitochondrial function." @default.
- W1887118332 created "2016-06-24" @default.
- W1887118332 creator A5000975558 @default.
- W1887118332 creator A5041307323 @default.
- W1887118332 creator A5055595014 @default.
- W1887118332 creator A5060367646 @default.
- W1887118332 creator A5071961324 @default.
- W1887118332 creator A5079609531 @default.
- W1887118332 date "2015-09-11" @default.
- W1887118332 modified "2023-09-25" @default.
- W1887118332 title "Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components" @default.
- W1887118332 cites W1855150270 @default.
- W1887118332 cites W1970587959 @default.
- W1887118332 cites W1974408096 @default.
- W1887118332 cites W1979368624 @default.
- W1887118332 cites W1980267283 @default.
- W1887118332 cites W1980515769 @default.
- W1887118332 cites W1984971377 @default.
- W1887118332 cites W1995321922 @default.
- W1887118332 cites W2014689439 @default.
- W1887118332 cites W2015872365 @default.
- W1887118332 cites W2022915755 @default.
- W1887118332 cites W2029351168 @default.
- W1887118332 cites W2033422521 @default.
- W1887118332 cites W2039725515 @default.
- W1887118332 cites W2042923512 @default.
- W1887118332 cites W2044151078 @default.
- W1887118332 cites W2049811173 @default.
- W1887118332 cites W2051240076 @default.
- W1887118332 cites W2055339952 @default.
- W1887118332 cites W2056617276 @default.
- W1887118332 cites W2059494962 @default.
- W1887118332 cites W2059643569 @default.
- W1887118332 cites W2074243279 @default.
- W1887118332 cites W2074965288 @default.
- W1887118332 cites W2080712061 @default.
- W1887118332 cites W2090606446 @default.
- W1887118332 cites W2090742622 @default.
- W1887118332 cites W2091746744 @default.
- W1887118332 cites W2094645185 @default.
- W1887118332 cites W2105404724 @default.
- W1887118332 cites W2116386358 @default.
- W1887118332 cites W2126866334 @default.
- W1887118332 cites W2129267808 @default.
- W1887118332 cites W2138844585 @default.
- W1887118332 cites W2141486452 @default.
- W1887118332 cites W2143011549 @default.
- W1887118332 cites W2144408459 @default.
- W1887118332 cites W2166790314 @default.
- W1887118332 cites W2169824758 @default.
- W1887118332 cites W2324756735 @default.
- W1887118332 doi "https://doi.org/10.3390/molecules200916524" @default.
- W1887118332 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6331980" @default.
- W1887118332 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26378512" @default.
- W1887118332 hasPublicationYear "2015" @default.
- W1887118332 type Work @default.
- W1887118332 sameAs 1887118332 @default.
- W1887118332 citedByCount "11" @default.
- W1887118332 countsByYear W18871183322016 @default.
- W1887118332 countsByYear W18871183322017 @default.
- W1887118332 countsByYear W18871183322019 @default.
- W1887118332 countsByYear W18871183322020 @default.
- W1887118332 countsByYear W18871183322021 @default.
- W1887118332 countsByYear W18871183322022 @default.
- W1887118332 countsByYear W18871183322023 @default.
- W1887118332 crossrefType "journal-article" @default.
- W1887118332 hasAuthorship W1887118332A5000975558 @default.
- W1887118332 hasAuthorship W1887118332A5041307323 @default.
- W1887118332 hasAuthorship W1887118332A5055595014 @default.
- W1887118332 hasAuthorship W1887118332A5060367646 @default.
- W1887118332 hasAuthorship W1887118332A5071961324 @default.
- W1887118332 hasAuthorship W1887118332A5079609531 @default.
- W1887118332 hasBestOaLocation W18871183321 @default.
- W1887118332 hasConcept C126322002 @default.
- W1887118332 hasConcept C14036430 @default.
- W1887118332 hasConcept C185592680 @default.
- W1887118332 hasConcept C2776925932 @default.
- W1887118332 hasConcept C2777229759 @default.
- W1887118332 hasConcept C2777551382 @default.
- W1887118332 hasConcept C2778004101 @default.
- W1887118332 hasConcept C2778250585 @default.
- W1887118332 hasConcept C2778310972 @default.
- W1887118332 hasConcept C2779134260 @default.
- W1887118332 hasConcept C2781449162 @default.
- W1887118332 hasConcept C28859421 @default.
- W1887118332 hasConcept C55493867 @default.
- W1887118332 hasConcept C70899900 @default.
- W1887118332 hasConcept C71924100 @default.
- W1887118332 hasConcept C86803240 @default.
- W1887118332 hasConcept C95444343 @default.
- W1887118332 hasConcept C98274493 @default.
- W1887118332 hasConceptScore W1887118332C126322002 @default.
- W1887118332 hasConceptScore W1887118332C14036430 @default.
- W1887118332 hasConceptScore W1887118332C185592680 @default.
- W1887118332 hasConceptScore W1887118332C2776925932 @default.
- W1887118332 hasConceptScore W1887118332C2777229759 @default.
- W1887118332 hasConceptScore W1887118332C2777551382 @default.
- W1887118332 hasConceptScore W1887118332C2778004101 @default.