FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W188815566> ?p ?o ?g. }

• W188815566 endingPage "5" @default.
• W188815566 startingPage "501" @default.
• W188815566 abstract "This study aimed to test the feasibility of spironolactone treatment in comparison with a surfactant in the early stage of acute respiratory distress syndrome (ARDS) in rats, as assessed by the acute lung injury (ALI) score, blood gas, brain natriuretic peptide (BNP) and N-terminal pro-brain natriuretic peptide (NT-proBNP).A total of 40 rats were randomly allocated into one of five groups (n is eight). The baseline group (Group B) was subjected to neither tracheotomy nor ARDS induction, while the sham group (Group N) was subjected to tracheotomy upon ARDS induction by acid aspiration. The other three groups were administered either a single dose of spironolactone (100 mg/kg, Group Sp) or surfactant (100 mg/kg, Group S), or were untreated (Group A). Blood samples were collected from the femoral artery for blood gases, BNP and NT-proBNP measurements.ARDS induction decreased the blood PO2 /FiO2 ratio and increased the BNP and NT-proBNP levels (p is less than 0.001). Compared with the ARDS-untreated group, spironolactone treatment was more effective at reducing the elevated BNP (72 percent versus 37 percent) and NT-proBNP (53 percent versus 23 percent) levels and ALI score (28 percent versus 7 percent) than surfactant treatment. Moreover, the blood PO2 / FiO2 ratio was negatively correlated with the BNP (r is -0.79), NT-proBNP (r is -0.85) and ALI scores (r is -0.85).Spironolactone is an effective form of treatment for ARDS at an early stage, as reflected by an increased blood O2 /FiO2 ratio, decreased BNP and NT-proBNP levels, and ALI score." @default.
• W188815566 created "2016-06-24" @default.
• W188815566 creator A5008536278 @default.
• W188815566 creator A5024961448 @default.
• W188815566 creator A5055609344 @default.
• W188815566 creator A5068862843 @default.
• W188815566 creator A5077031553 @default.
• W188815566 date "2010-06-01" @default.
• W188815566 modified "2023-10-11" @default.
• W188815566 title "The efficacy of spironolactone in the treatment of acute respiratory distress syndrome-induced rats." @default.
• W188815566 cites W1971305507 @default.
• W188815566 cites W1978393770 @default.
• W188815566 cites W1979691648 @default.
• W188815566 cites W1983221818 @default.
• W188815566 cites W1987411396 @default.
• W188815566 cites W1987413490 @default.
• W188815566 cites W1988816170 @default.
• W188815566 cites W2000267911 @default.
• W188815566 cites W2005357317 @default.
• W188815566 cites W2024224109 @default.
• W188815566 cites W2026521622 @default.
• W188815566 cites W2049426749 @default.
• W188815566 cites W2050348223 @default.
• W188815566 cites W2051486282 @default.
• W188815566 cites W2090921019 @default.
• W188815566 cites W2101201730 @default.
• W188815566 cites W2106493153 @default.
• W188815566 cites W2109879469 @default.
• W188815566 cites W2125470888 @default.
• W188815566 cites W2126554704 @default.
• W188815566 cites W2129306951 @default.
• W188815566 cites W2131687335 @default.
• W188815566 cites W2140753070 @default.
• W188815566 cites W2167504169 @default.
• W188815566 cites W2171194138 @default.
• W188815566 cites W2333411966 @default.
• W188815566 cites W2345300991 @default.
• W188815566 cites W26622030 @default.
• W188815566 cites W96804527 @default.
• W188815566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20658111" @default.
• W188815566 hasPublicationYear "2010" @default.
• W188815566 type Work @default.
• W188815566 sameAs 188815566 @default.
• W188815566 citedByCount "6" @default.
• W188815566 countsByYear W1888155662013 @default.
• W188815566 countsByYear W1888155662016 @default.
• W188815566 countsByYear W1888155662020 @default.
• W188815566 countsByYear W1888155662022 @default.
• W188815566 crossrefType "journal-article" @default.
• W188815566 hasAuthorship W188815566A5008536278 @default.
• W188815566 hasAuthorship W188815566A5024961448 @default.
• W188815566 hasAuthorship W188815566A5055609344 @default.
• W188815566 hasAuthorship W188815566A5068862843 @default.
• W188815566 hasAuthorship W188815566A5077031553 @default.
• W188815566 hasConcept C126322002 @default.
• W188815566 hasConcept C141983124 @default.
• W188815566 hasConcept C2775846464 @default.
• W188815566 hasConcept C2776348555 @default.
• W188815566 hasConcept C2776379505 @default.
• W188815566 hasConcept C2777714996 @default.
• W188815566 hasConcept C2778198053 @default.
• W188815566 hasConcept C2778525890 @default.
• W188815566 hasConcept C2779537118 @default.
• W188815566 hasConcept C42219234 @default.
• W188815566 hasConcept C71924100 @default.
• W188815566 hasConcept C90924648 @default.
• W188815566 hasConceptScore W188815566C126322002 @default.
• W188815566 hasConceptScore W188815566C141983124 @default.
• W188815566 hasConceptScore W188815566C2775846464 @default.
• W188815566 hasConceptScore W188815566C2776348555 @default.
• W188815566 hasConceptScore W188815566C2776379505 @default.
• W188815566 hasConceptScore W188815566C2777714996 @default.
• W188815566 hasConceptScore W188815566C2778198053 @default.
• W188815566 hasConceptScore W188815566C2778525890 @default.
• W188815566 hasConceptScore W188815566C2779537118 @default.
• W188815566 hasConceptScore W188815566C42219234 @default.
• W188815566 hasConceptScore W188815566C71924100 @default.
• W188815566 hasConceptScore W188815566C90924648 @default.
• W188815566 hasIssue "6" @default.
• W188815566 hasLocation W1888155661 @default.
• W188815566 hasOpenAccess W188815566 @default.
• W188815566 hasPrimaryLocation W1888155661 @default.
• W188815566 hasRelatedWork W1982125375 @default.
• W188815566 hasRelatedWork W2045240349 @default.
• W188815566 hasRelatedWork W2108444173 @default.
• W188815566 hasRelatedWork W2168895700 @default.
• W188815566 hasRelatedWork W2352050331 @default.
• W188815566 hasRelatedWork W2352589853 @default.
• W188815566 hasRelatedWork W2354063579 @default.
• W188815566 hasRelatedWork W2354177604 @default.
• W188815566 hasRelatedWork W2358070615 @default.
• W188815566 hasRelatedWork W2361351754 @default.
• W188815566 hasRelatedWork W2364636005 @default.
• W188815566 hasRelatedWork W2368283475 @default.
• W188815566 hasRelatedWork W2374097581 @default.
• W188815566 hasRelatedWork W2374423540 @default.
• W188815566 hasRelatedWork W2375305029 @default.
• W188815566 hasRelatedWork W2376877908 @default.

• next