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- W188859954 abstract "As early as 1971, it was noted that smoking marijuana lowered intraocular pressure. In this study one of the active components of marijuana, delta-9-tetrahydrocannabinol, was given intravenously to ten subjects with normal intraocular pressures. Two strengths were used--0.022 mg/kg of body weight and 0.044 mg/kg of body weight. Intraocular pressure was found to decrease as much as 51% of baseline normal with an average decrease of 37%. Heart rate increased in a range of 22% and 65% of the resting pulse. Respiratory rate was not affected. No analgesic properties were demonstrated by either cutaneous or periosteal stimulation. Anxiety levels were increased by delta-9-tetrahydrocannabinol over placebo and diazepam (Valium). The mechanism of action is still uncertain but it is believed by some workers to be similar to that of a beta-adrenergic stimulator." @default.
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- W188859954 date "1976-01-01" @default.
- W188859954 modified "2023-09-23" @default.
- W188859954 title "The Effect of Delta-9-Tetrahydrocannabinol on Intraocular Pressure in Humans" @default.
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- W188859954 doi "https://doi.org/10.1007/978-1-4613-4286-1_6" @default.
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