FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1888784858> ?p ?o ?g. }

• W1888784858 endingPage "134" @default.
• W1888784858 startingPage "134" @default.
• W1888784858 abstract "Curcumin provides various biological effects through its anti-inflammatory and antioxidant properties. Moreover, curcumin exerts a neuroprotective effect against ischemic condition-induced brain damage. Protein phosphatase 2A (PP2A) is a ubiquitous serine and threonine phosphatase with various cell functions and broad substrate specificity. Especially PP2A subunit B plays an important role in nervous system. This study investigated whether curcumin regulates PP2A subunit B expression in focal cerebral ischemia. Cerebral ischemia was induced surgically by middle cerebral artery occlusion (MCAO). Adult male rats were injected with either vehicle or curcumin (50 mg/kg) 1 h after MCAO and cerebral cortex tissues were isolated 24 h after MCAO. A proteomics study, reverse transverse-PCR and Western blot analyses were performed to examine PP2A subunit B expression levels. We identified a reduction in PP2A subunit B expression in MCAO-operated animals using a proteomic approach. However, curcumin treatment prevented injury-induced reductions in PP2A subunit B levels. Reverse transverse-PCR and Western blot analyses confirmed that curcumin treatment attenuated the injury-induced reduction in PP2A subunit B levels. These findings can suggest that the possibility that curcumin maintains levels of PP2A subunit B in response to cerebral ischemia, which likely contributes to the neuroprotective function of curcumin in cerebral ischemic injury." @default.
• W1888784858 created "2016-06-24" @default.
• W1888784858 creator A5015008662 @default.
• W1888784858 creator A5049500230 @default.
• W1888784858 creator A5078219070 @default.
• W1888784858 creator A5091473479 @default.
• W1888784858 date "2015-01-01" @default.
• W1888784858 modified "2023-10-14" @default.
• W1888784858 title "Curcumin treatment recovery the decrease of protein phosphatase 2A subunit B induced by focal cerebral ischemia in Sprague-Dawley rats" @default.
• W1888784858 cites W152204717 @default.
• W1888784858 cites W1829131178 @default.
• W1888784858 cites W195118146 @default.
• W1888784858 cites W1971185265 @default.
• W1888784858 cites W1986499908 @default.
• W1888784858 cites W1988790557 @default.
• W1888784858 cites W1999793253 @default.
• W1888784858 cites W2011085845 @default.
• W1888784858 cites W2027213610 @default.
• W1888784858 cites W2028746615 @default.
• W1888784858 cites W2036093656 @default.
• W1888784858 cites W2038638713 @default.
• W1888784858 cites W2039994452 @default.
• W1888784858 cites W2043854033 @default.
• W1888784858 cites W2045696000 @default.
• W1888784858 cites W2045811396 @default.
• W1888784858 cites W2050781125 @default.
• W1888784858 cites W2055433327 @default.
• W1888784858 cites W2057849450 @default.
• W1888784858 cites W2066893159 @default.
• W1888784858 cites W2069691760 @default.
• W1888784858 cites W2070172912 @default.
• W1888784858 cites W2070978834 @default.
• W1888784858 cites W2074810969 @default.
• W1888784858 cites W2104841476 @default.
• W1888784858 cites W2111066733 @default.
• W1888784858 cites W2112505121 @default.
• W1888784858 cites W2121119677 @default.
• W1888784858 cites W2125079080 @default.
• W1888784858 cites W2142970302 @default.
• W1888784858 cites W4240253200 @default.
• W1888784858 doi "https://doi.org/10.5625/lar.2015.31.3.134" @default.
• W1888784858 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4602080" @default.
• W1888784858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26472966" @default.
• W1888784858 hasPublicationYear "2015" @default.
• W1888784858 type Work @default.
• W1888784858 sameAs 1888784858 @default.
• W1888784858 citedByCount "12" @default.
• W1888784858 countsByYear W18887848582016 @default.
• W1888784858 countsByYear W18887848582017 @default.
• W1888784858 countsByYear W18887848582018 @default.
• W1888784858 countsByYear W18887848582019 @default.
• W1888784858 countsByYear W18887848582021 @default.
• W1888784858 countsByYear W18887848582022 @default.
• W1888784858 countsByYear W18887848582023 @default.
• W1888784858 crossrefType "journal-article" @default.
• W1888784858 hasAuthorship W1888784858A5015008662 @default.
• W1888784858 hasAuthorship W1888784858A5049500230 @default.
• W1888784858 hasAuthorship W1888784858A5078219070 @default.
• W1888784858 hasAuthorship W1888784858A5091473479 @default.
• W1888784858 hasBestOaLocation W18887848581 @default.
• W1888784858 hasConcept C104292427 @default.
• W1888784858 hasConcept C104317684 @default.
• W1888784858 hasConcept C11960822 @default.
• W1888784858 hasConcept C126322002 @default.
• W1888784858 hasConcept C178666793 @default.
• W1888784858 hasConcept C185592680 @default.
• W1888784858 hasConcept C25498285 @default.
• W1888784858 hasConcept C2776415932 @default.
• W1888784858 hasConcept C2778250585 @default.
• W1888784858 hasConcept C389152 @default.
• W1888784858 hasConcept C541997718 @default.
• W1888784858 hasConcept C55493867 @default.
• W1888784858 hasConcept C71924100 @default.
• W1888784858 hasConcept C98274493 @default.
• W1888784858 hasConceptScore W1888784858C104292427 @default.
• W1888784858 hasConceptScore W1888784858C104317684 @default.
• W1888784858 hasConceptScore W1888784858C11960822 @default.
• W1888784858 hasConceptScore W1888784858C126322002 @default.
• W1888784858 hasConceptScore W1888784858C178666793 @default.
• W1888784858 hasConceptScore W1888784858C185592680 @default.
• W1888784858 hasConceptScore W1888784858C25498285 @default.
• W1888784858 hasConceptScore W1888784858C2776415932 @default.
• W1888784858 hasConceptScore W1888784858C2778250585 @default.
• W1888784858 hasConceptScore W1888784858C389152 @default.
• W1888784858 hasConceptScore W1888784858C541997718 @default.
• W1888784858 hasConceptScore W1888784858C55493867 @default.
• W1888784858 hasConceptScore W1888784858C71924100 @default.
• W1888784858 hasConceptScore W1888784858C98274493 @default.
• W1888784858 hasIssue "3" @default.
• W1888784858 hasLocation W18887848581 @default.
• W1888784858 hasLocation W18887848582 @default.
• W1888784858 hasLocation W18887848583 @default.
• W1888784858 hasLocation W18887848584 @default.
• W1888784858 hasOpenAccess W1888784858 @default.
• W1888784858 hasPrimaryLocation W18887848581 @default.
• W1888784858 hasRelatedWork W1538431955 @default.
• W1888784858 hasRelatedWork W1587432739 @default.
• W1888784858 hasRelatedWork W1888784858 @default.

• next