Matches in SemOpenAlex for { <https://semopenalex.org/work/W1889104080> ?p ?o ?g. }
- W1889104080 endingPage "313" @default.
- W1889104080 startingPage "307" @default.
- W1889104080 abstract "The objective of this study is to optimize the levels of carbon and nitrogen sources of the medium in shake flask experiments and evaluate the effect of pH and dissolved oxygen (DO) on the production of L-asparaginase from a newly isolated Serratia marcescens SK-07 in a batch bioreactor.Central composite rotatable design (CCRD) was applied to optimize the levels of carbon and nitrogen sources of the medium in shake flask experiments. The optimal levels of L-asparagine, glucose, yeast extract and peptone were found to be 4·93, 3·81, 3·65 and 1·47 g l⁻¹, respectively, and maximal L-asparaginase production of 25·02 U mg⁻¹ was obtained under these conditions. Among the carbon sources tested, L-asparagine was identified to be the most favourable carbon source for enhanced production of L-asparaginase. The maximum L-asparaginase production of 29·89 U mg⁻¹ was achieved in a batch bioreactor at initial pH of 6·5 (uncontrolled) and DO level of 40% in the culture.We have isolated, screened and identified the potential micro-organism, S. marcescens, for the production of L-asparaginase. An overall 5·55-fold increase in the production was achieved under optimal levels of carbon and nitrogen sources, DO level and at initial pH of 6·5 (uncontrolled).The experiments illustrate the importance of statistical method for optimization of carbon and nitrogen sources and study the effect of physical process parameters on the production of L-asparaginase in shake flask and bioreactor, respectively. This study would be helpful for bioprocess development of bacterial L-asparaginase production." @default.
- W1889104080 created "2016-06-24" @default.
- W1889104080 creator A5038338413 @default.
- W1889104080 creator A5053056924 @default.
- W1889104080 creator A5060037706 @default.
- W1889104080 date "2011-02-15" @default.
- W1889104080 modified "2023-09-27" @default.
- W1889104080 title "Effect of chemical and physical parameters on the production of l-asparaginase from a newly isolated Serratia marcescens SK-07" @default.
- W1889104080 cites W1531685260 @default.
- W1889104080 cites W1677287410 @default.
- W1889104080 cites W1775749144 @default.
- W1889104080 cites W1970963500 @default.
- W1889104080 cites W1984617845 @default.
- W1889104080 cites W1999136344 @default.
- W1889104080 cites W2000052414 @default.
- W1889104080 cites W2001992796 @default.
- W1889104080 cites W2009674410 @default.
- W1889104080 cites W2022648960 @default.
- W1889104080 cites W2024571603 @default.
- W1889104080 cites W2035698184 @default.
- W1889104080 cites W2036299552 @default.
- W1889104080 cites W2065619350 @default.
- W1889104080 cites W2079630019 @default.
- W1889104080 cites W2088096285 @default.
- W1889104080 cites W2107419838 @default.
- W1889104080 cites W4249383959 @default.
- W1889104080 doi "https://doi.org/10.1111/j.1472-765x.2011.03006.x" @default.
- W1889104080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21231939" @default.
- W1889104080 hasPublicationYear "2011" @default.
- W1889104080 type Work @default.
- W1889104080 sameAs 1889104080 @default.
- W1889104080 citedByCount "20" @default.
- W1889104080 countsByYear W18891040802012 @default.
- W1889104080 countsByYear W18891040802013 @default.
- W1889104080 countsByYear W18891040802014 @default.
- W1889104080 countsByYear W18891040802015 @default.
- W1889104080 countsByYear W18891040802016 @default.
- W1889104080 countsByYear W18891040802017 @default.
- W1889104080 countsByYear W18891040802018 @default.
- W1889104080 countsByYear W18891040802019 @default.
- W1889104080 countsByYear W18891040802020 @default.
- W1889104080 countsByYear W18891040802022 @default.
- W1889104080 crossrefType "journal-article" @default.
- W1889104080 hasAuthorship W1889104080A5038338413 @default.
- W1889104080 hasAuthorship W1889104080A5053056924 @default.
- W1889104080 hasAuthorship W1889104080A5060037706 @default.
- W1889104080 hasBestOaLocation W18891040801 @default.
- W1889104080 hasConcept C100544194 @default.
- W1889104080 hasConcept C104317684 @default.
- W1889104080 hasConcept C104779481 @default.
- W1889104080 hasConcept C140205800 @default.
- W1889104080 hasConcept C145890019 @default.
- W1889104080 hasConcept C159985019 @default.
- W1889104080 hasConcept C168170006 @default.
- W1889104080 hasConcept C178790620 @default.
- W1889104080 hasConcept C181199279 @default.
- W1889104080 hasConcept C185592680 @default.
- W1889104080 hasConcept C192562407 @default.
- W1889104080 hasConcept C2775895851 @default.
- W1889104080 hasConcept C2776309202 @default.
- W1889104080 hasConcept C2778461978 @default.
- W1889104080 hasConcept C2778904437 @default.
- W1889104080 hasConcept C2909962599 @default.
- W1889104080 hasConcept C2982740256 @default.
- W1889104080 hasConcept C31903555 @default.
- W1889104080 hasConcept C43617362 @default.
- W1889104080 hasConcept C537208039 @default.
- W1889104080 hasConcept C54355233 @default.
- W1889104080 hasConcept C547475151 @default.
- W1889104080 hasConcept C55493867 @default.
- W1889104080 hasConcept C86803240 @default.
- W1889104080 hasConceptScore W1889104080C100544194 @default.
- W1889104080 hasConceptScore W1889104080C104317684 @default.
- W1889104080 hasConceptScore W1889104080C104779481 @default.
- W1889104080 hasConceptScore W1889104080C140205800 @default.
- W1889104080 hasConceptScore W1889104080C145890019 @default.
- W1889104080 hasConceptScore W1889104080C159985019 @default.
- W1889104080 hasConceptScore W1889104080C168170006 @default.
- W1889104080 hasConceptScore W1889104080C178790620 @default.
- W1889104080 hasConceptScore W1889104080C181199279 @default.
- W1889104080 hasConceptScore W1889104080C185592680 @default.
- W1889104080 hasConceptScore W1889104080C192562407 @default.
- W1889104080 hasConceptScore W1889104080C2775895851 @default.
- W1889104080 hasConceptScore W1889104080C2776309202 @default.
- W1889104080 hasConceptScore W1889104080C2778461978 @default.
- W1889104080 hasConceptScore W1889104080C2778904437 @default.
- W1889104080 hasConceptScore W1889104080C2909962599 @default.
- W1889104080 hasConceptScore W1889104080C2982740256 @default.
- W1889104080 hasConceptScore W1889104080C31903555 @default.
- W1889104080 hasConceptScore W1889104080C43617362 @default.
- W1889104080 hasConceptScore W1889104080C537208039 @default.
- W1889104080 hasConceptScore W1889104080C54355233 @default.
- W1889104080 hasConceptScore W1889104080C547475151 @default.
- W1889104080 hasConceptScore W1889104080C55493867 @default.
- W1889104080 hasConceptScore W1889104080C86803240 @default.
- W1889104080 hasIssue "4" @default.
- W1889104080 hasLocation W18891040801 @default.
- W1889104080 hasLocation W18891040802 @default.