Matches in SemOpenAlex for { <https://semopenalex.org/work/W189028045> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W189028045 endingPage "31" @default.
- W189028045 startingPage "115" @default.
- W189028045 abstract "Exercise induces extensive generation of reactive oxygen species, which are responsible for tissue damage: enzymes inactivation, lipid peroxidation and single strand breaks in DNA. Defense system against free radicals is consisting of enzymes such as superoxide dismutase, catalase, glutathione peroxidase, and numerous non-enzymatic antioxidants. The study was performed to evaluate the effect of a single bout of submaximal running exercise, on the lymphocyte DNA strand breaks and also to test how supplementation with tempol - a membrane-permeable SOD-mimetic (0.2 mmol/kg/day) influences the eventually evoked damage. Male, Wistar rats were challenged with graded 50 min. running on treadmill at intensity up to 75-85% of predicted VO(2)max. The DNA strand breaks in individual lymphocytes were determined by using a gel electrophoretic technique - comet assay. We found substantial lymphocyte DNA damage 60 min. after the exercise. Tempol failed to prevent from oxidative damage in rats challenged with exercise. Moreover tempol by itself induced higher DNA damage than the exercise bout." @default.
- W189028045 created "2016-06-24" @default.
- W189028045 creator A5013495721 @default.
- W189028045 creator A5036414871 @default.
- W189028045 creator A5038105619 @default.
- W189028045 creator A5059439478 @default.
- W189028045 date "2006-11-01" @default.
- W189028045 modified "2023-10-18" @default.
- W189028045 title "Lymphocyte DNA damage in rats challenged with a single bout of strenuous exercise." @default.
- W189028045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17242495" @default.
- W189028045 hasPublicationYear "2006" @default.
- W189028045 type Work @default.
- W189028045 sameAs 189028045 @default.
- W189028045 citedByCount "10" @default.
- W189028045 countsByYear W1890280452012 @default.
- W189028045 countsByYear W1890280452015 @default.
- W189028045 countsByYear W1890280452016 @default.
- W189028045 countsByYear W1890280452023 @default.
- W189028045 crossrefType "journal-article" @default.
- W189028045 hasAuthorship W189028045A5013495721 @default.
- W189028045 hasAuthorship W189028045A5036414871 @default.
- W189028045 hasAuthorship W189028045A5038105619 @default.
- W189028045 hasAuthorship W189028045A5059439478 @default.
- W189028045 hasConcept C126322002 @default.
- W189028045 hasConcept C143425029 @default.
- W189028045 hasConcept C185592680 @default.
- W189028045 hasConcept C2775838275 @default.
- W189028045 hasConcept C2776151105 @default.
- W189028045 hasConcept C2777761686 @default.
- W189028045 hasConcept C2778760513 @default.
- W189028045 hasConcept C2778979269 @default.
- W189028045 hasConcept C2780358455 @default.
- W189028045 hasConcept C2780829032 @default.
- W189028045 hasConcept C48349386 @default.
- W189028045 hasConcept C552990157 @default.
- W189028045 hasConcept C55493867 @default.
- W189028045 hasConcept C71924100 @default.
- W189028045 hasConceptScore W189028045C126322002 @default.
- W189028045 hasConceptScore W189028045C143425029 @default.
- W189028045 hasConceptScore W189028045C185592680 @default.
- W189028045 hasConceptScore W189028045C2775838275 @default.
- W189028045 hasConceptScore W189028045C2776151105 @default.
- W189028045 hasConceptScore W189028045C2777761686 @default.
- W189028045 hasConceptScore W189028045C2778760513 @default.
- W189028045 hasConceptScore W189028045C2778979269 @default.
- W189028045 hasConceptScore W189028045C2780358455 @default.
- W189028045 hasConceptScore W189028045C2780829032 @default.
- W189028045 hasConceptScore W189028045C48349386 @default.
- W189028045 hasConceptScore W189028045C552990157 @default.
- W189028045 hasConceptScore W189028045C55493867 @default.
- W189028045 hasConceptScore W189028045C71924100 @default.
- W189028045 hasLocation W1890280451 @default.
- W189028045 hasOpenAccess W189028045 @default.
- W189028045 hasPrimaryLocation W1890280451 @default.
- W189028045 hasRelatedWork W189028045 @default.
- W189028045 hasRelatedWork W1895588679 @default.
- W189028045 hasRelatedWork W1972543156 @default.
- W189028045 hasRelatedWork W1993548188 @default.
- W189028045 hasRelatedWork W2017357811 @default.
- W189028045 hasRelatedWork W2030366229 @default.
- W189028045 hasRelatedWork W2065747472 @default.
- W189028045 hasRelatedWork W2172052736 @default.
- W189028045 hasRelatedWork W2367305450 @default.
- W189028045 hasRelatedWork W4285037963 @default.
- W189028045 hasVolume "57 Suppl 10" @default.
- W189028045 isParatext "false" @default.
- W189028045 isRetracted "false" @default.
- W189028045 magId "189028045" @default.
- W189028045 workType "article" @default.