FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1890870166> ?p ?o ?g. }

• W1890870166 endingPage "54" @default.
• W1890870166 startingPage "41" @default.
• W1890870166 abstract "The aim of the present work was to study the preparation and characteristics of sustained-release microspheres. As a model drug, sodium diclofenac was encapsulated in microspheres of the polymer Eudragit RS by using a double emulsion–solvent evaporation method. Investigations were carried out on the effects of the preparation method, the rate of the first step of emulsification, and the phase volume and composition (drug and additives) on the physical parameters of the product: its drug encapsulation, and the drug release. We evaluated the resulting microsphere structure [by differential scanning calorimetry (DSC)], the particle size, the surface area (by scanning electron microscopy), the entrapment and encapsulation efficiency (applying a novel method, energy-dispersive x-ray fluorescence analysis), the viscosity of the primary emulsion, and the organic solvent residue (by gas chromatography). We also evaluated and compared the samples by means of the kinetic data relating to drug release. The particle size could be decreased to one third by increasing the external aqueous phase ratio. In the first step of emulsification, elevation of the stirring rate led to microspheres with unfavorable characteristics. Increase of the active agent content and the plasticizer concentration had opposite effects. We applied a covalently not bound plasticizer, which was shown to influence the structure of the microspheres considerably. Drug Dev. Res. 64:41–54, 2005. © 2005 Wiley-Liss, Inc." @default.
• W1890870166 created "2016-06-24" @default.
• W1890870166 creator A5020772600 @default.
• W1890870166 creator A5022462561 @default.
• W1890870166 creator A5023611952 @default.
• W1890870166 creator A5054143787 @default.
• W1890870166 creator A5062326075 @default.
• W1890870166 date "2005-01-01" @default.
• W1890870166 modified "2023-10-18" @default.
• W1890870166 title "Influence of preparation conditions on the properties of Eudragit microspheres produced by a double emulsion method" @default.
• W1890870166 cites W1557469254 @default.
• W1890870166 cites W1968983438 @default.
• W1890870166 cites W1974933001 @default.
• W1890870166 cites W1988684693 @default.
• W1890870166 cites W2003742048 @default.
• W1890870166 cites W2007337976 @default.
• W1890870166 cites W2007746492 @default.
• W1890870166 cites W2009523551 @default.
• W1890870166 cites W2011192062 @default.
• W1890870166 cites W2016656813 @default.
• W1890870166 cites W2026061792 @default.
• W1890870166 cites W2038550135 @default.
• W1890870166 cites W2043789726 @default.
• W1890870166 cites W2047255590 @default.
• W1890870166 cites W2050009863 @default.
• W1890870166 cites W2058339985 @default.
• W1890870166 cites W2059104154 @default.
• W1890870166 cites W2062866402 @default.
• W1890870166 cites W2066202831 @default.
• W1890870166 cites W2070410358 @default.
• W1890870166 cites W2083719812 @default.
• W1890870166 cites W2086130473 @default.
• W1890870166 cites W2094598829 @default.
• W1890870166 cites W2120867526 @default.
• W1890870166 cites W2155751766 @default.
• W1890870166 cites W2280680688 @default.
• W1890870166 cites W4252629618 @default.
• W1890870166 doi "https://doi.org/10.1002/ddr.10425" @default.
• W1890870166 hasPublicationYear "2005" @default.
• W1890870166 type Work @default.
• W1890870166 sameAs 1890870166 @default.
• W1890870166 citedByCount "22" @default.
• W1890870166 countsByYear W18908701662012 @default.
• W1890870166 countsByYear W18908701662013 @default.
• W1890870166 countsByYear W18908701662014 @default.
• W1890870166 countsByYear W18908701662015 @default.
• W1890870166 countsByYear W18908701662017 @default.
• W1890870166 countsByYear W18908701662018 @default.
• W1890870166 countsByYear W18908701662019 @default.
• W1890870166 crossrefType "journal-article" @default.
• W1890870166 hasAuthorship W1890870166A5020772600 @default.
• W1890870166 hasAuthorship W1890870166A5022462561 @default.
• W1890870166 hasAuthorship W1890870166A5023611952 @default.
• W1890870166 hasAuthorship W1890870166A5054143787 @default.
• W1890870166 hasAuthorship W1890870166A5062326075 @default.
• W1890870166 hasConcept C121332964 @default.
• W1890870166 hasConcept C127413603 @default.
• W1890870166 hasConcept C147789679 @default.
• W1890870166 hasConcept C159985019 @default.
• W1890870166 hasConcept C178790620 @default.
• W1890870166 hasConcept C185592680 @default.
• W1890870166 hasConcept C187530423 @default.
• W1890870166 hasConcept C192562407 @default.
• W1890870166 hasConcept C26771246 @default.
• W1890870166 hasConcept C2777521759 @default.
• W1890870166 hasConcept C2778123984 @default.
• W1890870166 hasConcept C2780471494 @default.
• W1890870166 hasConcept C39519442 @default.
• W1890870166 hasConcept C42360764 @default.
• W1890870166 hasConcept C43617362 @default.
• W1890870166 hasConcept C58968531 @default.
• W1890870166 hasConcept C97355855 @default.
• W1890870166 hasConceptScore W1890870166C121332964 @default.
• W1890870166 hasConceptScore W1890870166C127413603 @default.
• W1890870166 hasConceptScore W1890870166C147789679 @default.
• W1890870166 hasConceptScore W1890870166C159985019 @default.
• W1890870166 hasConceptScore W1890870166C178790620 @default.
• W1890870166 hasConceptScore W1890870166C185592680 @default.
• W1890870166 hasConceptScore W1890870166C187530423 @default.
• W1890870166 hasConceptScore W1890870166C192562407 @default.
• W1890870166 hasConceptScore W1890870166C26771246 @default.
• W1890870166 hasConceptScore W1890870166C2777521759 @default.
• W1890870166 hasConceptScore W1890870166C2778123984 @default.
• W1890870166 hasConceptScore W1890870166C2780471494 @default.
• W1890870166 hasConceptScore W1890870166C39519442 @default.
• W1890870166 hasConceptScore W1890870166C42360764 @default.
• W1890870166 hasConceptScore W1890870166C43617362 @default.
• W1890870166 hasConceptScore W1890870166C58968531 @default.
• W1890870166 hasConceptScore W1890870166C97355855 @default.
• W1890870166 hasIssue "1" @default.
• W1890870166 hasLocation W18908701661 @default.
• W1890870166 hasOpenAccess W1890870166 @default.
• W1890870166 hasPrimaryLocation W18908701661 @default.
• W1890870166 hasRelatedWork W2001018507 @default.
• W1890870166 hasRelatedWork W2030379177 @default.
• W1890870166 hasRelatedWork W2053499275 @default.
• W1890870166 hasRelatedWork W2072515419 @default.
• W1890870166 hasRelatedWork W2095667463 @default.

• next