Matches in SemOpenAlex for { <https://semopenalex.org/work/W1890989648> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W1890989648 endingPage "6" @default.
- W1890989648 startingPage "622" @default.
- W1890989648 abstract "Granulocytes from 21 nonasthmatic cystic fibrosis (CF) patients were isolated and the effects of isoproterenol, histamine, and prostaglandin E1 upon zymosan-induced beta-glucuronidase release was measured. Granulocytes from CF patients contained significantly less total beta-glucuronidase activity compared with those from control subjects, but response to zymosan stimulation was normal. Compared with those from control subjects, the granulocytes from CF patients with severe airway disease (% predicted FEV1 less than 60) had significantly reduced responsiveness to isoproterenol, which correlated with both the % predicted FEV1 values and the NIH clinical score. In this same population of CF patients, granulocyte responsiveness to PGE1 was also decreased compared with that of the control subjects, but the degree of impairment was not as severe as that observed with isoproterenol nor did it correlate with disease severity. Histamine responsiveness, however, was normal. Our findings suggest that abnormal beta-adrenergic responses may reflect the severity of airway disease and clinical score." @default.
- W1890989648 created "2016-06-24" @default.
- W1890989648 creator A5031055479 @default.
- W1890989648 creator A5032844814 @default.
- W1890989648 creator A5044980958 @default.
- W1890989648 creator A5049871412 @default.
- W1890989648 creator A5072965164 @default.
- W1890989648 date "1981-06-01" @default.
- W1890989648 modified "2023-09-23" @default.
- W1890989648 title "Analysis of granulocyte beta-adrenergic response in cystic fibrosis: correlation of decreased responsiveness with disease severity." @default.
- W1890989648 doi "https://doi.org/10.1164/arrd.1981.123.6.622" @default.
- W1890989648 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7271056" @default.
- W1890989648 hasPublicationYear "1981" @default.
- W1890989648 type Work @default.
- W1890989648 sameAs 1890989648 @default.
- W1890989648 citedByCount "4" @default.
- W1890989648 crossrefType "journal-article" @default.
- W1890989648 hasAuthorship W1890989648A5031055479 @default.
- W1890989648 hasAuthorship W1890989648A5032844814 @default.
- W1890989648 hasAuthorship W1890989648A5044980958 @default.
- W1890989648 hasAuthorship W1890989648A5049871412 @default.
- W1890989648 hasAuthorship W1890989648A5072965164 @default.
- W1890989648 hasConcept C1122143 @default.
- W1890989648 hasConcept C126322002 @default.
- W1890989648 hasConcept C134018914 @default.
- W1890989648 hasConcept C158453852 @default.
- W1890989648 hasConcept C170493617 @default.
- W1890989648 hasConcept C202751555 @default.
- W1890989648 hasConcept C203014093 @default.
- W1890989648 hasConcept C24998067 @default.
- W1890989648 hasConcept C2776938444 @default.
- W1890989648 hasConcept C2777983669 @default.
- W1890989648 hasConcept C2778870864 @default.
- W1890989648 hasConcept C2908647359 @default.
- W1890989648 hasConcept C55493867 @default.
- W1890989648 hasConcept C71924100 @default.
- W1890989648 hasConcept C86803240 @default.
- W1890989648 hasConcept C90924648 @default.
- W1890989648 hasConcept C99454951 @default.
- W1890989648 hasConceptScore W1890989648C1122143 @default.
- W1890989648 hasConceptScore W1890989648C126322002 @default.
- W1890989648 hasConceptScore W1890989648C134018914 @default.
- W1890989648 hasConceptScore W1890989648C158453852 @default.
- W1890989648 hasConceptScore W1890989648C170493617 @default.
- W1890989648 hasConceptScore W1890989648C202751555 @default.
- W1890989648 hasConceptScore W1890989648C203014093 @default.
- W1890989648 hasConceptScore W1890989648C24998067 @default.
- W1890989648 hasConceptScore W1890989648C2776938444 @default.
- W1890989648 hasConceptScore W1890989648C2777983669 @default.
- W1890989648 hasConceptScore W1890989648C2778870864 @default.
- W1890989648 hasConceptScore W1890989648C2908647359 @default.
- W1890989648 hasConceptScore W1890989648C55493867 @default.
- W1890989648 hasConceptScore W1890989648C71924100 @default.
- W1890989648 hasConceptScore W1890989648C86803240 @default.
- W1890989648 hasConceptScore W1890989648C90924648 @default.
- W1890989648 hasConceptScore W1890989648C99454951 @default.
- W1890989648 hasIssue "6" @default.
- W1890989648 hasLocation W18909896481 @default.
- W1890989648 hasOpenAccess W1890989648 @default.
- W1890989648 hasPrimaryLocation W18909896481 @default.
- W1890989648 hasRelatedWork W1890989648 @default.
- W1890989648 hasRelatedWork W1988819859 @default.
- W1890989648 hasRelatedWork W2011989849 @default.
- W1890989648 hasRelatedWork W2012777163 @default.
- W1890989648 hasRelatedWork W2033761402 @default.
- W1890989648 hasRelatedWork W2062851024 @default.
- W1890989648 hasRelatedWork W2091557746 @default.
- W1890989648 hasRelatedWork W2155663970 @default.
- W1890989648 hasRelatedWork W2343147030 @default.
- W1890989648 hasRelatedWork W4229566329 @default.
- W1890989648 hasVolume "123" @default.
- W1890989648 isParatext "false" @default.
- W1890989648 isRetracted "false" @default.
- W1890989648 magId "1890989648" @default.
- W1890989648 workType "article" @default.