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- W1892209037 endingPage "608" @default.
- W1892209037 startingPage "591" @default.
- W1892209037 abstract "How a developing organ grows and patterns to its final shape is an important question in developmental biology. Studies of growth and patterning in the Drosophila wing imaginal disc have identified a key player, the morphogen Decapentaplegic (Dpp). These studies provided insights into our understanding of growth control and scaling: expansion of the Dpp gradient correlated with the growth of the tissue. A recent report on growth of a Drosophila organ other than the wing, the eye imaginal disc, prompts a reconsideration of our models of growth control. Despite striking differences between the two, the Dpp gradient scales with the target tissues of both organs and the growth of both the wing and the eye is controlled by Dpp. The goal of this review is to discuss whether a parsimonious model of scaling and growth control can explain the relationship between the Dpp gradient and growth in these two different developmental systems." @default.
- W1892209037 created "2016-06-24" @default.
- W1892209037 creator A5019038095 @default.
- W1892209037 creator A5065934696 @default.
- W1892209037 creator A5068186030 @default.
- W1892209037 creator A5080597344 @default.
- W1892209037 date "2015-06-24" @default.
- W1892209037 modified "2023-09-30" @default.
- W1892209037 title "The wing and the eye: a parsimonious theory for scaling and growth control?" @default.
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- W1892209037 doi "https://doi.org/10.1002/wdev.195" @default.
- W1892209037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26108346" @default.
- W1892209037 hasPublicationYear "2015" @default.