Matches in SemOpenAlex for { <https://semopenalex.org/work/W1892298036> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1892298036 endingPage "459" @default.
- W1892298036 startingPage "453" @default.
- W1892298036 abstract "1. Ketorolac is an investigational non-opioid analgesic. Buprenorphine, an opioid compound and diclofenac, a non-steroidal anti-inflammatory, are analgesics used in clinical practise. 2. The psychomotor effects of ketorolac (30 mg), buprenorphine (0.3 mg), diclofenac (50 mg) and placebo all administered i.m., were examined in 12 healthy male volunteers (age 19-38 years), up to 8 h post-dose. 3. Creatine phosphokinase (CPK) was measured up to 24 h post-dose, providing an indication of local tissue damage following injection. 4. Buprenorphine caused significant psychomotor impairment in seven out of eight psychomotor tests. The effects consistently peaked 4 h post-dose and were still apparent in many cases 8 h post-dose. These psychomotor effects were supported by marked symptoms in all volunteers. 5. Ketorolac and diclofenac had no clinically significant effects on psychomotor tests and only minimal symptoms were reported. 6. Diclofenac caused a marked increased in CPK (mean Cmax 298 iu l-1) compared with ketorolac (mean Cmax 70 iu l-1) and buprenorphine (mean Cmax 68 iu l-1). 7. These results suggest that ketorolac and diclofenac are suitable for administration following day case surgery." @default.
- W1892298036 created "2016-06-24" @default.
- W1892298036 creator A5005522934 @default.
- W1892298036 creator A5046417936 @default.
- W1892298036 creator A5046689036 @default.
- W1892298036 creator A5053859273 @default.
- W1892298036 date "1989-04-01" @default.
- W1892298036 modified "2023-10-16" @default.
- W1892298036 title "Psychomotor effects of ketorolac in comparison with buprenorphine and diclofenac [see comments]" @default.
- W1892298036 cites W1545823900 @default.
- W1892298036 cites W1973717599 @default.
- W1892298036 cites W2014795606 @default.
- W1892298036 cites W2016494227 @default.
- W1892298036 cites W2073925912 @default.
- W1892298036 cites W2079902803 @default.
- W1892298036 cites W2083064925 @default.
- W1892298036 cites W2421871926 @default.
- W1892298036 doi "https://doi.org/10.1111/j.1365-2125.1989.tb05393.x" @default.
- W1892298036 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1379724" @default.
- W1892298036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2785813" @default.
- W1892298036 hasPublicationYear "1989" @default.
- W1892298036 type Work @default.
- W1892298036 sameAs 1892298036 @default.
- W1892298036 citedByCount "62" @default.
- W1892298036 countsByYear W18922980362012 @default.
- W1892298036 countsByYear W18922980362013 @default.
- W1892298036 countsByYear W18922980362017 @default.
- W1892298036 countsByYear W18922980362018 @default.
- W1892298036 countsByYear W18922980362019 @default.
- W1892298036 countsByYear W18922980362020 @default.
- W1892298036 crossrefType "journal-article" @default.
- W1892298036 hasAuthorship W1892298036A5005522934 @default.
- W1892298036 hasAuthorship W1892298036A5046417936 @default.
- W1892298036 hasAuthorship W1892298036A5046689036 @default.
- W1892298036 hasAuthorship W1892298036A5053859273 @default.
- W1892298036 hasBestOaLocation W18922980362 @default.
- W1892298036 hasConcept C112705442 @default.
- W1892298036 hasConcept C118552586 @default.
- W1892298036 hasConcept C126322002 @default.
- W1892298036 hasConcept C142724271 @default.
- W1892298036 hasConcept C164953862 @default.
- W1892298036 hasConcept C169900460 @default.
- W1892298036 hasConcept C170493617 @default.
- W1892298036 hasConcept C204787440 @default.
- W1892298036 hasConcept C22979827 @default.
- W1892298036 hasConcept C27081682 @default.
- W1892298036 hasConcept C2778446825 @default.
- W1892298036 hasConcept C2778949969 @default.
- W1892298036 hasConcept C2779826273 @default.
- W1892298036 hasConcept C2780820201 @default.
- W1892298036 hasConcept C2781063702 @default.
- W1892298036 hasConcept C42219234 @default.
- W1892298036 hasConcept C71924100 @default.
- W1892298036 hasConcept C98274493 @default.
- W1892298036 hasConceptScore W1892298036C112705442 @default.
- W1892298036 hasConceptScore W1892298036C118552586 @default.
- W1892298036 hasConceptScore W1892298036C126322002 @default.
- W1892298036 hasConceptScore W1892298036C142724271 @default.
- W1892298036 hasConceptScore W1892298036C164953862 @default.
- W1892298036 hasConceptScore W1892298036C169900460 @default.
- W1892298036 hasConceptScore W1892298036C170493617 @default.
- W1892298036 hasConceptScore W1892298036C204787440 @default.
- W1892298036 hasConceptScore W1892298036C22979827 @default.
- W1892298036 hasConceptScore W1892298036C27081682 @default.
- W1892298036 hasConceptScore W1892298036C2778446825 @default.
- W1892298036 hasConceptScore W1892298036C2778949969 @default.
- W1892298036 hasConceptScore W1892298036C2779826273 @default.
- W1892298036 hasConceptScore W1892298036C2780820201 @default.
- W1892298036 hasConceptScore W1892298036C2781063702 @default.
- W1892298036 hasConceptScore W1892298036C42219234 @default.
- W1892298036 hasConceptScore W1892298036C71924100 @default.
- W1892298036 hasConceptScore W1892298036C98274493 @default.
- W1892298036 hasIssue "4" @default.
- W1892298036 hasLocation W18922980361 @default.
- W1892298036 hasLocation W18922980362 @default.
- W1892298036 hasLocation W18922980363 @default.
- W1892298036 hasLocation W18922980364 @default.
- W1892298036 hasOpenAccess W1892298036 @default.
- W1892298036 hasPrimaryLocation W18922980361 @default.
- W1892298036 hasRelatedWork W117411119 @default.
- W1892298036 hasRelatedWork W2007461192 @default.
- W1892298036 hasRelatedWork W2012546774 @default.
- W1892298036 hasRelatedWork W2017357698 @default.
- W1892298036 hasRelatedWork W2018474001 @default.
- W1892298036 hasRelatedWork W2039966502 @default.
- W1892298036 hasRelatedWork W2075683469 @default.
- W1892298036 hasRelatedWork W2123996794 @default.
- W1892298036 hasRelatedWork W2165747316 @default.
- W1892298036 hasRelatedWork W2166939717 @default.
- W1892298036 hasVolume "27" @default.
- W1892298036 isParatext "false" @default.
- W1892298036 isRetracted "false" @default.
- W1892298036 magId "1892298036" @default.
- W1892298036 workType "article" @default.