Matches in SemOpenAlex for { <https://semopenalex.org/work/W18929574> ?p ?o ?g. }
- W18929574 endingPage "24" @default.
- W18929574 startingPage "16" @default.
- W18929574 abstract "Tumor necrosis factor (TNF) is able to induce a great diversity of cellular responses via modulating the expression of a number of different genes. The multitude of TNF activities may be explained by both structural and functional heterogeneity in TNF receptors as well as by a diversification of postreceptor signal transduction pathways. Purification of TNF receptors has revealed two major, distinct binding proteins (TR60 and TR80). TR60 seems to be an essential component for TNF signaling; the functional role of TR80 remains to be elucidated. The pathway of postreceptor signal transduction involves phospholipase A2, a phosphatidylcholine-specific phospholipase C, protein kinase C, and other serine/threonine and tyrosine-specific protein kinases with as yet unknown function. At the receiving end of TNF signaling, induction of gene expression is mediated through activation of nuclear transcription factors, such as NFkB, AP-1, IRF-1, and NF-GMa." @default.
- W18929574 created "2016-06-24" @default.
- W18929574 creator A5010497925 @default.
- W18929574 creator A5070597784 @default.
- W18929574 creator A5086472692 @default.
- W18929574 date "1992-04-01" @default.
- W18929574 modified "2023-09-23" @default.
- W18929574 title "Mechanisms of tumor necrosis factor action." @default.
- W18929574 cites W129757728 @default.
- W18929574 cites W1504047855 @default.
- W18929574 cites W1512393880 @default.
- W18929574 cites W1516043257 @default.
- W18929574 cites W1531074822 @default.
- W18929574 cites W1536347913 @default.
- W18929574 cites W1539182279 @default.
- W18929574 cites W1552669957 @default.
- W18929574 cites W1556753095 @default.
- W18929574 cites W1557531431 @default.
- W18929574 cites W1568518323 @default.
- W18929574 cites W1581410949 @default.
- W18929574 cites W1596123405 @default.
- W18929574 cites W166095048 @default.
- W18929574 cites W1776295853 @default.
- W18929574 cites W1965168699 @default.
- W18929574 cites W1968213454 @default.
- W18929574 cites W1968713831 @default.
- W18929574 cites W1971514924 @default.
- W18929574 cites W1977348907 @default.
- W18929574 cites W1986954033 @default.
- W18929574 cites W1987722323 @default.
- W18929574 cites W1993667392 @default.
- W18929574 cites W1997219067 @default.
- W18929574 cites W1999246265 @default.
- W18929574 cites W2003896199 @default.
- W18929574 cites W2005484362 @default.
- W18929574 cites W2019735634 @default.
- W18929574 cites W2023447656 @default.
- W18929574 cites W2023857134 @default.
- W18929574 cites W2025187365 @default.
- W18929574 cites W2031089158 @default.
- W18929574 cites W2031991869 @default.
- W18929574 cites W2033684442 @default.
- W18929574 cites W2033727409 @default.
- W18929574 cites W2034652137 @default.
- W18929574 cites W2037772620 @default.
- W18929574 cites W2039428188 @default.
- W18929574 cites W2043127339 @default.
- W18929574 cites W2043541788 @default.
- W18929574 cites W2044218480 @default.
- W18929574 cites W2047688511 @default.
- W18929574 cites W2048325240 @default.
- W18929574 cites W2049038993 @default.
- W18929574 cites W2051867686 @default.
- W18929574 cites W2056376839 @default.
- W18929574 cites W2058100123 @default.
- W18929574 cites W2061903251 @default.
- W18929574 cites W2070737639 @default.
- W18929574 cites W2076200943 @default.
- W18929574 cites W2077856196 @default.
- W18929574 cites W2078960968 @default.
- W18929574 cites W2080784424 @default.
- W18929574 cites W2083508061 @default.
- W18929574 cites W2089372467 @default.
- W18929574 cites W2091734110 @default.
- W18929574 cites W2095296343 @default.
- W18929574 cites W2117716734 @default.
- W18929574 cites W2127145932 @default.
- W18929574 cites W2146101256 @default.
- W18929574 cites W2151000863 @default.
- W18929574 cites W2157026533 @default.
- W18929574 cites W2162367837 @default.
- W18929574 cites W2164658118 @default.
- W18929574 cites W2168098703 @default.
- W18929574 cites W221489722 @default.
- W18929574 cites W2395739455 @default.
- W18929574 cites W2397769233 @default.
- W18929574 cites W3145981933 @default.
- W18929574 cites W337120153 @default.
- W18929574 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1313193" @default.
- W18929574 hasPublicationYear "1992" @default.
- W18929574 type Work @default.
- W18929574 sameAs 18929574 @default.
- W18929574 citedByCount "38" @default.
- W18929574 countsByYear W189295742012 @default.
- W18929574 countsByYear W189295742013 @default.
- W18929574 countsByYear W189295742015 @default.
- W18929574 countsByYear W189295742016 @default.
- W18929574 countsByYear W189295742019 @default.
- W18929574 countsByYear W189295742022 @default.
- W18929574 crossrefType "journal-article" @default.
- W18929574 hasAuthorship W18929574A5010497925 @default.
- W18929574 hasAuthorship W18929574A5070597784 @default.
- W18929574 hasAuthorship W18929574A5086472692 @default.
- W18929574 hasConcept C104317684 @default.
- W18929574 hasConcept C170493617 @default.
- W18929574 hasConcept C17991360 @default.
- W18929574 hasConcept C184235292 @default.
- W18929574 hasConcept C203014093 @default.