Matches in SemOpenAlex for { <https://semopenalex.org/work/W1893224725> ?p ?o ?g. }
- W1893224725 endingPage "828" @default.
- W1893224725 startingPage "818" @default.
- W1893224725 abstract "Aging of the reproductive system has been studied in numerous vertebrate species. Although there are wide variations in reproductive strategies and hormone cycle components, many of the fundamental changes that occur during aging are similar. Evolutionary hypotheses attempt to explain why menopause occurs, whereas cellular hypotheses attempt to explain how it occurs. It is commonly believed that a disruption in the hypothalamic-pituitary-gonadal axis is responsible for the onset of menopause. Data exist to demonstrate that the first signs of menopause occur at the level of the brain or the ovary. Thus, finding an appropriate and representative animal model is especially important for the advancement of menopause research. In primates, there is a gradual decline in the function of the hypothalamic-pituitary-gonadal (HPG) axis ultimately resulting in irregularities in menstrual cycles and increasingly sporadic incidence of ovulation. Rodents also exhibit a progressive deterioration in HPG axis function; however, they also experience a period of constant estrus accompanied by intermittent ovulations, reduced progesterone levels, and elevated circulating estradiol levels. It is remarkable to observe that females of other classes also demonstrate deterioration in HPG axis function and ovarian failure. Comparisons of aging in various taxa provide insight into fundamental biological mechanisms of aging that could underlie reproductive decline." @default.
- W1893224725 created "2016-06-24" @default.
- W1893224725 creator A5016735317 @default.
- W1893224725 creator A5030336965 @default.
- W1893224725 creator A5039555071 @default.
- W1893224725 creator A5044264789 @default.
- W1893224725 date "2005-12-01" @default.
- W1893224725 modified "2023-09-27" @default.
- W1893224725 title "Ovarian Aging and Menopause: Current Theories, Hypotheses, and Research Models" @default.
- W1893224725 cites W1550251946 @default.
- W1893224725 cites W1577859676 @default.
- W1893224725 cites W1600610840 @default.
- W1893224725 cites W16282355 @default.
- W1893224725 cites W1968249925 @default.
- W1893224725 cites W1972448905 @default.
- W1893224725 cites W1974975856 @default.
- W1893224725 cites W1976631136 @default.
- W1893224725 cites W1985823173 @default.
- W1893224725 cites W1989643757 @default.
- W1893224725 cites W1990355089 @default.
- W1893224725 cites W1991303866 @default.
- W1893224725 cites W1993642198 @default.
- W1893224725 cites W1995780952 @default.
- W1893224725 cites W2003340724 @default.
- W1893224725 cites W2009159536 @default.
- W1893224725 cites W2013481652 @default.
- W1893224725 cites W2019572526 @default.
- W1893224725 cites W2022356766 @default.
- W1893224725 cites W2023076624 @default.
- W1893224725 cites W2023095530 @default.
- W1893224725 cites W2024472446 @default.
- W1893224725 cites W2025233095 @default.
- W1893224725 cites W2028021946 @default.
- W1893224725 cites W2029131356 @default.
- W1893224725 cites W2029422876 @default.
- W1893224725 cites W2031454887 @default.
- W1893224725 cites W2033873142 @default.
- W1893224725 cites W2037341437 @default.
- W1893224725 cites W2038988941 @default.
- W1893224725 cites W2041932804 @default.
- W1893224725 cites W2043159791 @default.
- W1893224725 cites W2043979841 @default.
- W1893224725 cites W2044593903 @default.
- W1893224725 cites W2045476680 @default.
- W1893224725 cites W2047247552 @default.
- W1893224725 cites W2048124239 @default.
- W1893224725 cites W2048697586 @default.
- W1893224725 cites W2049107009 @default.
- W1893224725 cites W2051348661 @default.
- W1893224725 cites W2057713336 @default.
- W1893224725 cites W2059502203 @default.
- W1893224725 cites W2063557787 @default.
- W1893224725 cites W2063809442 @default.
- W1893224725 cites W2067258086 @default.
- W1893224725 cites W2068311282 @default.
- W1893224725 cites W2073687053 @default.
- W1893224725 cites W2076604159 @default.
- W1893224725 cites W2077180087 @default.
- W1893224725 cites W2077332834 @default.
- W1893224725 cites W2079394706 @default.
- W1893224725 cites W2080902740 @default.
- W1893224725 cites W2083158575 @default.
- W1893224725 cites W2087602948 @default.
- W1893224725 cites W2095353799 @default.
- W1893224725 cites W2096555371 @default.
- W1893224725 cites W2097270150 @default.
- W1893224725 cites W2101266059 @default.
- W1893224725 cites W2102021233 @default.
- W1893224725 cites W2111701671 @default.
- W1893224725 cites W2115053548 @default.
- W1893224725 cites W2118981894 @default.
- W1893224725 cites W2124157801 @default.
- W1893224725 cites W2129222018 @default.
- W1893224725 cites W2131280745 @default.
- W1893224725 cites W2131303835 @default.
- W1893224725 cites W2134755119 @default.
- W1893224725 cites W2134979684 @default.
- W1893224725 cites W2135624258 @default.
- W1893224725 cites W2142525992 @default.
- W1893224725 cites W2149967205 @default.
- W1893224725 cites W2150392329 @default.
- W1893224725 cites W2152001263 @default.
- W1893224725 cites W2152046955 @default.
- W1893224725 cites W2153000015 @default.
- W1893224725 cites W2157999278 @default.
- W1893224725 cites W2160151670 @default.
- W1893224725 cites W2161591122 @default.
- W1893224725 cites W2169222380 @default.
- W1893224725 cites W2331073645 @default.
- W1893224725 cites W2409825417 @default.
- W1893224725 cites W2768469806 @default.
- W1893224725 cites W3023516284 @default.
- W1893224725 cites W4240471373 @default.
- W1893224725 cites W4378949049 @default.
- W1893224725 doi "https://doi.org/10.1177/153537020523001106" @default.
- W1893224725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16339746" @default.
- W1893224725 hasPublicationYear "2005" @default.
- W1893224725 type Work @default.