Matches in SemOpenAlex for { <https://semopenalex.org/work/W1893387083> ?p ?o ?g. }
- W1893387083 endingPage "282" @default.
- W1893387083 startingPage "278" @default.
- W1893387083 abstract "Human entorhinal cortex (ERC) connects the temporal neocortex with hippocampus and is essential for memory retrieval and navigation. Markedly, there have been only few quantitative MRI works on the ERC geometric measurements in pediatric and adult healthy subjects across the lifespan. Here, we sought to fill this gap in knowledge by quantifying the ERC thickness in a very large cohort of subjects spanning 9 decades of life.Using magnetic resonance imaging data from multiple centers (IXI, MMRR, NKI, OASIS combined with the NIH-Child Dev database and locally recruited healthy subjects), we analyzed the lifespan trajectory of ERC thickness in 1,660 healthy controls ranging from 2 to 94 years of age.The ERC thickness increased with age, reached a peak at about 44 years, and then decreased with age. ERC thickness is hemispherically rightward-asymmetric with no gender differences. Mean ERC thickness was found to vary between 2.943 ± .438 mm and 3.525 ± .355 mm across different age populations. Also, more pronounced loss of the ERC thickness in healthy aging men was noticeable.Our report with high spatial resolution brain MRI data from 1,660 healthy controls provided important clues about ERC thickness across lifespan. We believe that our report will pave the way for the future studies investigating distinct neural pathologies related with cognitive dysfunctions." @default.
- W1893387083 created "2016-06-24" @default.
- W1893387083 creator A5021143842 @default.
- W1893387083 creator A5022342401 @default.
- W1893387083 creator A5032357963 @default.
- W1893387083 creator A5032643831 @default.
- W1893387083 creator A5042927878 @default.
- W1893387083 creator A5073296164 @default.
- W1893387083 creator A5074378595 @default.
- W1893387083 creator A5082192669 @default.
- W1893387083 creator A5083972529 @default.
- W1893387083 date "2015-10-08" @default.
- W1893387083 modified "2023-09-26" @default.
- W1893387083 title "Entorhinal Cortex Thickness across the Human Lifespan" @default.
- W1893387083 cites W1515540534 @default.
- W1893387083 cites W1516136717 @default.
- W1893387083 cites W1582218424 @default.
- W1893387083 cites W1789491764 @default.
- W1893387083 cites W1966100017 @default.
- W1893387083 cites W1968723344 @default.
- W1893387083 cites W1979114778 @default.
- W1893387083 cites W1992395739 @default.
- W1893387083 cites W1992936223 @default.
- W1893387083 cites W1995123816 @default.
- W1893387083 cites W1995485453 @default.
- W1893387083 cites W1999972116 @default.
- W1893387083 cites W2020139159 @default.
- W1893387083 cites W2023831571 @default.
- W1893387083 cites W2036619684 @default.
- W1893387083 cites W2037689983 @default.
- W1893387083 cites W2040268226 @default.
- W1893387083 cites W2040759402 @default.
- W1893387083 cites W2041520556 @default.
- W1893387083 cites W2044225191 @default.
- W1893387083 cites W2046572522 @default.
- W1893387083 cites W2047051692 @default.
- W1893387083 cites W2061404811 @default.
- W1893387083 cites W2066470779 @default.
- W1893387083 cites W2076592929 @default.
- W1893387083 cites W2082939309 @default.
- W1893387083 cites W2098816522 @default.
- W1893387083 cites W2101135654 @default.
- W1893387083 cites W2102496376 @default.
- W1893387083 cites W2105416775 @default.
- W1893387083 cites W2105549490 @default.
- W1893387083 cites W2108995275 @default.
- W1893387083 cites W2114926230 @default.
- W1893387083 cites W2117102945 @default.
- W1893387083 cites W2120973488 @default.
- W1893387083 cites W2122358852 @default.
- W1893387083 cites W2123687120 @default.
- W1893387083 cites W2126999263 @default.
- W1893387083 cites W2127324977 @default.
- W1893387083 cites W2134286053 @default.
- W1893387083 cites W2137284909 @default.
- W1893387083 cites W2139893960 @default.
- W1893387083 cites W2140854449 @default.
- W1893387083 cites W2146263384 @default.
- W1893387083 cites W2150534249 @default.
- W1893387083 cites W2154562349 @default.
- W1893387083 cites W2170537094 @default.
- W1893387083 cites W2171808809 @default.
- W1893387083 cites W2990728208 @default.
- W1893387083 doi "https://doi.org/10.1111/jon.12297" @default.
- W1893387083 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4826319" @default.
- W1893387083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26565394" @default.
- W1893387083 hasPublicationYear "2015" @default.
- W1893387083 type Work @default.
- W1893387083 sameAs 1893387083 @default.
- W1893387083 citedByCount "32" @default.
- W1893387083 countsByYear W18933870832016 @default.
- W1893387083 countsByYear W18933870832017 @default.
- W1893387083 countsByYear W18933870832018 @default.
- W1893387083 countsByYear W18933870832019 @default.
- W1893387083 countsByYear W18933870832020 @default.
- W1893387083 countsByYear W18933870832021 @default.
- W1893387083 countsByYear W18933870832022 @default.
- W1893387083 countsByYear W18933870832023 @default.
- W1893387083 crossrefType "journal-article" @default.
- W1893387083 hasAuthorship W1893387083A5021143842 @default.
- W1893387083 hasAuthorship W1893387083A5022342401 @default.
- W1893387083 hasAuthorship W1893387083A5032357963 @default.
- W1893387083 hasAuthorship W1893387083A5032643831 @default.
- W1893387083 hasAuthorship W1893387083A5042927878 @default.
- W1893387083 hasAuthorship W1893387083A5073296164 @default.
- W1893387083 hasAuthorship W1893387083A5074378595 @default.
- W1893387083 hasAuthorship W1893387083A5082192669 @default.
- W1893387083 hasAuthorship W1893387083A5083972529 @default.
- W1893387083 hasBestOaLocation W18933870832 @default.
- W1893387083 hasConcept C118552586 @default.
- W1893387083 hasConcept C126322002 @default.
- W1893387083 hasConcept C126838900 @default.
- W1893387083 hasConcept C143409427 @default.
- W1893387083 hasConcept C144024400 @default.
- W1893387083 hasConcept C149923435 @default.
- W1893387083 hasConcept C15744967 @default.
- W1893387083 hasConcept C164705383 @default.
- W1893387083 hasConcept C169760540 @default.