Matches in SemOpenAlex for { <https://semopenalex.org/work/W189346932> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W189346932 endingPage "5" @default.
- W189346932 startingPage "S50" @default.
- W189346932 abstract "Hepato- and nephrotoxicity can be induced by the exposure to cadmium (Cd). This toxicity can be detected by the elevation of blood biomarkers such as ALT AST, ALP BUN and creatinine. These elevations are found in small animals, e.g. mice and rats. However the alteration of biomarkers did not investigate in large animals, e.g. cattle. Hepato- and nephrotoxicity induced by cadmium can also be examined by the alterations of metallothionein (MT) and metal transcription factor-1 (MTF-1). To present study the expressions of these markers, the cattle were classified into five groups according to the levels of cadmium in the kidneys. ALT, AST andALP were analyzed to determine liver damage whereas BUN and creatinine were examined for kidney damage. The results showed that blood biomarkers were not sensitive enough to be correlated markers to cadmium induced hepato- and nephrotoxicity in cattle. The expressions of MT and MTF-1 protein were investigated by immunofluorescence method. The expressions of MT and MTF-1 proteins were firstly found in the cattle group which had low cadmium concentration in tissues (< 0.5 mg/kg). Thus, these proteins could be used as the sensitive markers to determine the cadmium exposure. The MT and MTF-1 gene expressions were also studied. However, there was no correlation between the level of RNA and the protein expressions due to the concentration of protein levels bearing unclear relationship with the mRNA level. The investigation of these protein expressions is very useful because the result can be used as a protective method to prevent consumption of cadmium-contaminated beef." @default.
- W189346932 created "2016-06-24" @default.
- W189346932 creator A5025267746 @default.
- W189346932 creator A5030640034 @default.
- W189346932 creator A5061005957 @default.
- W189346932 date "2011-10-01" @default.
- W189346932 modified "2023-09-23" @default.
- W189346932 title "Prediction of cadmium (Cd) toxicity in cattle." @default.
- W189346932 cites W1490999150 @default.
- W189346932 cites W1991855340 @default.
- W189346932 cites W2013150301 @default.
- W189346932 cites W2026093245 @default.
- W189346932 cites W2045310997 @default.
- W189346932 cites W2056063805 @default.
- W189346932 cites W2084468424 @default.
- W189346932 cites W2125847914 @default.
- W189346932 cites W2440269545 @default.
- W189346932 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22338927" @default.
- W189346932 hasPublicationYear "2011" @default.
- W189346932 type Work @default.
- W189346932 sameAs 189346932 @default.
- W189346932 citedByCount "1" @default.
- W189346932 countsByYear W1893469322022 @default.
- W189346932 crossrefType "journal-article" @default.
- W189346932 hasAuthorship W189346932A5025267746 @default.
- W189346932 hasAuthorship W189346932A5030640034 @default.
- W189346932 hasAuthorship W189346932A5061005957 @default.
- W189346932 hasConcept C126189478 @default.
- W189346932 hasConcept C126322002 @default.
- W189346932 hasConcept C134018914 @default.
- W189346932 hasConcept C16685009 @default.
- W189346932 hasConcept C178790620 @default.
- W189346932 hasConcept C185592680 @default.
- W189346932 hasConcept C20719415 @default.
- W189346932 hasConcept C2780091579 @default.
- W189346932 hasConcept C2780306776 @default.
- W189346932 hasConcept C29730261 @default.
- W189346932 hasConcept C544657597 @default.
- W189346932 hasConcept C71924100 @default.
- W189346932 hasConcept C86803240 @default.
- W189346932 hasConceptScore W189346932C126189478 @default.
- W189346932 hasConceptScore W189346932C126322002 @default.
- W189346932 hasConceptScore W189346932C134018914 @default.
- W189346932 hasConceptScore W189346932C16685009 @default.
- W189346932 hasConceptScore W189346932C178790620 @default.
- W189346932 hasConceptScore W189346932C185592680 @default.
- W189346932 hasConceptScore W189346932C20719415 @default.
- W189346932 hasConceptScore W189346932C2780091579 @default.
- W189346932 hasConceptScore W189346932C2780306776 @default.
- W189346932 hasConceptScore W189346932C29730261 @default.
- W189346932 hasConceptScore W189346932C544657597 @default.
- W189346932 hasConceptScore W189346932C71924100 @default.
- W189346932 hasConceptScore W189346932C86803240 @default.
- W189346932 hasLocation W1893469321 @default.
- W189346932 hasOpenAccess W189346932 @default.
- W189346932 hasPrimaryLocation W1893469321 @default.
- W189346932 hasRelatedWork W1972428116 @default.
- W189346932 hasRelatedWork W2001673838 @default.
- W189346932 hasRelatedWork W2006976610 @default.
- W189346932 hasRelatedWork W2045344854 @default.
- W189346932 hasRelatedWork W2064824611 @default.
- W189346932 hasRelatedWork W2074392964 @default.
- W189346932 hasRelatedWork W2075442325 @default.
- W189346932 hasRelatedWork W2106188053 @default.
- W189346932 hasRelatedWork W2405290615 @default.
- W189346932 hasRelatedWork W61150575 @default.
- W189346932 hasVolume "94 Suppl 5" @default.
- W189346932 isParatext "false" @default.
- W189346932 isRetracted "false" @default.
- W189346932 magId "189346932" @default.
- W189346932 workType "article" @default.