Matches in SemOpenAlex for { <https://semopenalex.org/work/W1893909223> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1893909223 endingPage "11" @default.
- W1893909223 startingPage "5107" @default.
- W1893909223 abstract "Irinotecan alone and plus mitomycin C have been proven to be effective as second-line chemotherapy for advanced gastric cancer. The objective of the present study was to compare the efficacy and safety of irinotecan alone (CA) and with mitomycin C (CM) in clinical practice.Between November 2006 and December 2011, 46 patients with advanced gastric cancer refractory to fluoropyrimidine and platinum were treated with CM (n=22) or CA (n=24).Baseline characteristics of the patients were similar in the two treatment groups, with the exception of the sex ratio. The median progression-free survival was 3.9 months in the CM arm and 3.7 months in the CA arm (p=0.25), and the median overall survival was 9.6 and 8.7 months (p=0.36), respectively. The overall response rate was 18% in the CA arm and 9% in the CM arm (p=0.38). Grade 3/4 neutropenia (45% vs. 25%), anemia (36% vs. 4%), febrile neutropenia (14% vs. 8%), anorexia (14% vs. 8%) tended to be higher in the CM arm than in the CA arm.Although the efficacy of CM and CA for advanced gastric cancer refractory to fluoropyrimidine and platinum was not significantly different, CM tended to lead to greater incidence of adverse events in clinical practice." @default.
- W1893909223 created "2016-06-24" @default.
- W1893909223 creator A5014047853 @default.
- W1893909223 creator A5015023308 @default.
- W1893909223 creator A5017951288 @default.
- W1893909223 creator A5032787627 @default.
- W1893909223 creator A5036438602 @default.
- W1893909223 creator A5040013839 @default.
- W1893909223 creator A5042401726 @default.
- W1893909223 creator A5045136564 @default.
- W1893909223 creator A5050871597 @default.
- W1893909223 creator A5056456991 @default.
- W1893909223 creator A5065692477 @default.
- W1893909223 creator A5076120991 @default.
- W1893909223 creator A5083668667 @default.
- W1893909223 creator A5087388222 @default.
- W1893909223 creator A5088724035 @default.
- W1893909223 date "2013-11-01" @default.
- W1893909223 modified "2023-09-27" @default.
- W1893909223 title "Non-randomized comparison between irinotecan plus mitomycin C and irinotecan alone in patients with advanced gastric cancer refractory to fluoropyrimidine and platinum." @default.
- W1893909223 cites W1976651872 @default.
- W1893909223 cites W2106787323 @default.
- W1893909223 cites W2153061032 @default.
- W1893909223 cites W2169094377 @default.
- W1893909223 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24222156" @default.
- W1893909223 hasPublicationYear "2013" @default.
- W1893909223 type Work @default.
- W1893909223 sameAs 1893909223 @default.
- W1893909223 citedByCount "1" @default.
- W1893909223 countsByYear W18939092232018 @default.
- W1893909223 crossrefType "journal-article" @default.
- W1893909223 hasAuthorship W1893909223A5014047853 @default.
- W1893909223 hasAuthorship W1893909223A5015023308 @default.
- W1893909223 hasAuthorship W1893909223A5017951288 @default.
- W1893909223 hasAuthorship W1893909223A5032787627 @default.
- W1893909223 hasAuthorship W1893909223A5036438602 @default.
- W1893909223 hasAuthorship W1893909223A5040013839 @default.
- W1893909223 hasAuthorship W1893909223A5042401726 @default.
- W1893909223 hasAuthorship W1893909223A5045136564 @default.
- W1893909223 hasAuthorship W1893909223A5050871597 @default.
- W1893909223 hasAuthorship W1893909223A5056456991 @default.
- W1893909223 hasAuthorship W1893909223A5065692477 @default.
- W1893909223 hasAuthorship W1893909223A5076120991 @default.
- W1893909223 hasAuthorship W1893909223A5083668667 @default.
- W1893909223 hasAuthorship W1893909223A5087388222 @default.
- W1893909223 hasAuthorship W1893909223A5088724035 @default.
- W1893909223 hasConcept C121332964 @default.
- W1893909223 hasConcept C121608353 @default.
- W1893909223 hasConcept C126322002 @default.
- W1893909223 hasConcept C141071460 @default.
- W1893909223 hasConcept C142424586 @default.
- W1893909223 hasConcept C197934379 @default.
- W1893909223 hasConcept C2776694085 @default.
- W1893909223 hasConcept C2777063308 @default.
- W1893909223 hasConcept C2778850193 @default.
- W1893909223 hasConcept C2779338040 @default.
- W1893909223 hasConcept C2780259306 @default.
- W1893909223 hasConcept C526805850 @default.
- W1893909223 hasConcept C71924100 @default.
- W1893909223 hasConcept C87355193 @default.
- W1893909223 hasConcept C90924648 @default.
- W1893909223 hasConceptScore W1893909223C121332964 @default.
- W1893909223 hasConceptScore W1893909223C121608353 @default.
- W1893909223 hasConceptScore W1893909223C126322002 @default.
- W1893909223 hasConceptScore W1893909223C141071460 @default.
- W1893909223 hasConceptScore W1893909223C142424586 @default.
- W1893909223 hasConceptScore W1893909223C197934379 @default.
- W1893909223 hasConceptScore W1893909223C2776694085 @default.
- W1893909223 hasConceptScore W1893909223C2777063308 @default.
- W1893909223 hasConceptScore W1893909223C2778850193 @default.
- W1893909223 hasConceptScore W1893909223C2779338040 @default.
- W1893909223 hasConceptScore W1893909223C2780259306 @default.
- W1893909223 hasConceptScore W1893909223C526805850 @default.
- W1893909223 hasConceptScore W1893909223C71924100 @default.
- W1893909223 hasConceptScore W1893909223C87355193 @default.
- W1893909223 hasConceptScore W1893909223C90924648 @default.
- W1893909223 hasIssue "11" @default.
- W1893909223 hasLocation W18939092231 @default.
- W1893909223 hasOpenAccess W1893909223 @default.
- W1893909223 hasPrimaryLocation W18939092231 @default.
- W1893909223 hasRelatedWork W1893909223 @default.
- W1893909223 hasRelatedWork W1952441553 @default.
- W1893909223 hasRelatedWork W1979420908 @default.
- W1893909223 hasRelatedWork W1988409157 @default.
- W1893909223 hasRelatedWork W2048648630 @default.
- W1893909223 hasRelatedWork W2098455424 @default.
- W1893909223 hasRelatedWork W2105216735 @default.
- W1893909223 hasRelatedWork W2319873980 @default.
- W1893909223 hasRelatedWork W2443672351 @default.
- W1893909223 hasRelatedWork W280698033 @default.
- W1893909223 hasVolume "33" @default.
- W1893909223 isParatext "false" @default.
- W1893909223 isRetracted "false" @default.
- W1893909223 magId "1893909223" @default.
- W1893909223 workType "article" @default.