Matches in SemOpenAlex for { <https://semopenalex.org/work/W189427349> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W189427349 endingPage "23" @default.
- W189427349 startingPage "718" @default.
- W189427349 abstract "Neutropenia is a common toxicity of systemic cytotoxic therapy. Neutropenic enterocolitis (NE) is a rare occurrence but can be fatal, subsequent to neutropenia. The exact incidence and frequency is difficult to establish, but is usually underestimated. It is often missed but has recently been appreciated with increasing frequency in solid tumours. NE was initially reported with taxenes but now an increasing number of chemotherapeutic drugs are implicated. NE incidence is expected to increase with the use of dose dense regimens, myeloablative cytotoxic protocols, tissue transplants, and emerging newer molecules. The usual presentation is often non-specific and often over shadowed by the symptomatology of primary malignant disease and toxicity symptoms of chemotherapy. The basis of diagnosis is clinical, radiological (ultra sound/CT scan), per operative findings, and eventually post mortem. Treatment options of this highly fatal phenomenon varies from conservative to early surgical intervention. NE is expected to be diagnosed with increasing frequency. The factors leading to it are mucosal injury, caecal distension with resultant ischaemia, cytotoxic drugs, and microbiological agents. A high index of clinical suspicion and an early diagnosis is paramount for better outcome. Irrespective of management employed, conservative or upfront surgical intervention, it has a poor out come with high mortality. A clinical suspicion, early diagnosis, and prompt management are the key to a better result. There is need to identify people at high risk by prognostic factors, large scale studies, and formulating consensus management guidelines. At present individualized risk assessment based strategy is advocated." @default.
- W189427349 created "2016-06-24" @default.
- W189427349 creator A5057250200 @default.
- W189427349 creator A5062893180 @default.
- W189427349 date "2012-07-01" @default.
- W189427349 modified "2023-09-23" @default.
- W189427349 title "Chemotherapy-induced neutropenic necrotizing enterocolitis: a review." @default.
- W189427349 cites W103788795 @default.
- W189427349 cites W1975101868 @default.
- W189427349 cites W1975540164 @default.
- W189427349 cites W1977502335 @default.
- W189427349 cites W1982144629 @default.
- W189427349 cites W1999532427 @default.
- W189427349 cites W1999873285 @default.
- W189427349 cites W2003010403 @default.
- W189427349 cites W2006086892 @default.
- W189427349 cites W2011723488 @default.
- W189427349 cites W2016059561 @default.
- W189427349 cites W2018817146 @default.
- W189427349 cites W2024933507 @default.
- W189427349 cites W2030957507 @default.
- W189427349 cites W2033046938 @default.
- W189427349 cites W2052487508 @default.
- W189427349 cites W2069931945 @default.
- W189427349 cites W2071342876 @default.
- W189427349 cites W2073411333 @default.
- W189427349 cites W2079836113 @default.
- W189427349 cites W2101348027 @default.
- W189427349 cites W2102172978 @default.
- W189427349 cites W2142650263 @default.
- W189427349 cites W2156546371 @default.
- W189427349 cites W2163237499 @default.
- W189427349 cites W2318433066 @default.
- W189427349 cites W5274588 @default.
- W189427349 cites W2013317396 @default.
- W189427349 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23866523" @default.
- W189427349 hasPublicationYear "2012" @default.
- W189427349 type Work @default.
- W189427349 sameAs 189427349 @default.
- W189427349 citedByCount "5" @default.
- W189427349 countsByYear W1894273492017 @default.
- W189427349 countsByYear W1894273492020 @default.
- W189427349 countsByYear W1894273492022 @default.
- W189427349 crossrefType "journal-article" @default.
- W189427349 hasAuthorship W189427349A5057250200 @default.
- W189427349 hasAuthorship W189427349A5062893180 @default.
- W189427349 hasConcept C120665830 @default.
- W189427349 hasConcept C121332964 @default.
- W189427349 hasConcept C141071460 @default.
- W189427349 hasConcept C177713679 @default.
- W189427349 hasConcept C187212893 @default.
- W189427349 hasConcept C2776694085 @default.
- W189427349 hasConcept C2777063308 @default.
- W189427349 hasConcept C2778850193 @default.
- W189427349 hasConcept C61511704 @default.
- W189427349 hasConcept C71924100 @default.
- W189427349 hasConceptScore W189427349C120665830 @default.
- W189427349 hasConceptScore W189427349C121332964 @default.
- W189427349 hasConceptScore W189427349C141071460 @default.
- W189427349 hasConceptScore W189427349C177713679 @default.
- W189427349 hasConceptScore W189427349C187212893 @default.
- W189427349 hasConceptScore W189427349C2776694085 @default.
- W189427349 hasConceptScore W189427349C2777063308 @default.
- W189427349 hasConceptScore W189427349C2778850193 @default.
- W189427349 hasConceptScore W189427349C61511704 @default.
- W189427349 hasConceptScore W189427349C71924100 @default.
- W189427349 hasIssue "7" @default.
- W189427349 hasLocation W1894273491 @default.
- W189427349 hasOpenAccess W189427349 @default.
- W189427349 hasPrimaryLocation W1894273491 @default.
- W189427349 hasRelatedWork W1698575940 @default.
- W189427349 hasRelatedWork W175863639 @default.
- W189427349 hasRelatedWork W1981236961 @default.
- W189427349 hasRelatedWork W2013330239 @default.
- W189427349 hasRelatedWork W2081019057 @default.
- W189427349 hasRelatedWork W2121734196 @default.
- W189427349 hasRelatedWork W2407451013 @default.
- W189427349 hasRelatedWork W2411954154 @default.
- W189427349 hasRelatedWork W2465789807 @default.
- W189427349 hasRelatedWork W3002700213 @default.
- W189427349 hasVolume "62" @default.
- W189427349 isParatext "false" @default.
- W189427349 isRetracted "false" @default.
- W189427349 magId "189427349" @default.
- W189427349 workType "article" @default.