Matches in SemOpenAlex for { <https://semopenalex.org/work/W1895129514> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1895129514 endingPage "8" @default.
- W1895129514 startingPage "381" @default.
- W1895129514 abstract "ImmuKnow is an in vitro diagnosis method that uses patient samples of whole blood polyclonally stimulated with phytohaemagglutinin. It also measures adenosine triphosphate (ATP) production by CD4+ T cells. The test aims to offer an objective and overall measurement of each individual's cellular immune response. The assay was designed with the idea of individually monitoring the immunosuppression administered to transplant patients. At the same time, it aims to help achieve a balance as a way of avoiding immunosuppression excess and the associated adverse effects (infections, cancer, etc.) or an immunosuppression defect and the subsequent risk of allograft rejection. The majority of studies that have evaluated its clinical usefulness display great diversity in terms of patient recruitment, the immunosuppressant treatment received, the clinical variables analysed and, above all, the time between performing ImmuKnow and the evaluated clinical event. The most consistent data show that this assay on CD4+ T cell functioning is useful for predicting the risk of infection in renal transplant patients. However, its use as a rejection risk indicator is unclear. Lastly, given the great variability of immune response amongst individuals and that of existing publications, it can be deduced that the isolated ImmuKnow value does not have diagnostic capacity and only individual serial monitoring could provide definitive assistance in clinical decision making and immunosuppressant treatment changes. Other aspects of ImmuKnow application in the clinical routine, such as assay cycles, require randomised prospective studies for more comprehensive information." @default.
- W1895129514 created "2016-06-24" @default.
- W1895129514 creator A5009492539 @default.
- W1895129514 creator A5016761924 @default.
- W1895129514 creator A5045854773 @default.
- W1895129514 date "2013-01-01" @default.
- W1895129514 modified "2023-09-24" @default.
- W1895129514 title "The usefulness of intracellular adenosine-5'-triphosphate measurement in CD4+ cells in renal transplant." @default.
- W1895129514 cites W1520683642 @default.
- W1895129514 cites W1524999411 @default.
- W1895129514 cites W1568106739 @default.
- W1895129514 cites W1665088674 @default.
- W1895129514 cites W1965533545 @default.
- W1895129514 cites W1977461643 @default.
- W1895129514 cites W1979417621 @default.
- W1895129514 cites W1984432364 @default.
- W1895129514 cites W1989439033 @default.
- W1895129514 cites W2010256207 @default.
- W1895129514 cites W2014324653 @default.
- W1895129514 cites W2045125735 @default.
- W1895129514 cites W2050221135 @default.
- W1895129514 cites W2051872988 @default.
- W1895129514 cites W2063759059 @default.
- W1895129514 cites W2077745633 @default.
- W1895129514 cites W2089297859 @default.
- W1895129514 cites W2117806510 @default.
- W1895129514 cites W2133372129 @default.
- W1895129514 cites W2134795478 @default.
- W1895129514 cites W2142261360 @default.
- W1895129514 cites W2151519246 @default.
- W1895129514 cites W2166069608 @default.
- W1895129514 cites W2331438304 @default.
- W1895129514 doi "https://doi.org/10.3265/nefrologia.pre2012.oct.11540" @default.
- W1895129514 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23640115" @default.
- W1895129514 hasPublicationYear "2013" @default.
- W1895129514 type Work @default.
- W1895129514 sameAs 1895129514 @default.
- W1895129514 citedByCount "0" @default.
- W1895129514 crossrefType "journal-article" @default.
- W1895129514 hasAuthorship W1895129514A5009492539 @default.
- W1895129514 hasAuthorship W1895129514A5016761924 @default.
- W1895129514 hasAuthorship W1895129514A5045854773 @default.
- W1895129514 hasConcept C126322002 @default.
- W1895129514 hasConcept C143998085 @default.
- W1895129514 hasConcept C177713679 @default.
- W1895129514 hasConcept C197934379 @default.
- W1895129514 hasConcept C203014093 @default.
- W1895129514 hasConcept C2780050583 @default.
- W1895129514 hasConcept C2780252810 @default.
- W1895129514 hasConcept C2780303639 @default.
- W1895129514 hasConcept C2911091166 @default.
- W1895129514 hasConcept C2992666275 @default.
- W1895129514 hasConcept C71924100 @default.
- W1895129514 hasConcept C8891405 @default.
- W1895129514 hasConceptScore W1895129514C126322002 @default.
- W1895129514 hasConceptScore W1895129514C143998085 @default.
- W1895129514 hasConceptScore W1895129514C177713679 @default.
- W1895129514 hasConceptScore W1895129514C197934379 @default.
- W1895129514 hasConceptScore W1895129514C203014093 @default.
- W1895129514 hasConceptScore W1895129514C2780050583 @default.
- W1895129514 hasConceptScore W1895129514C2780252810 @default.
- W1895129514 hasConceptScore W1895129514C2780303639 @default.
- W1895129514 hasConceptScore W1895129514C2911091166 @default.
- W1895129514 hasConceptScore W1895129514C2992666275 @default.
- W1895129514 hasConceptScore W1895129514C71924100 @default.
- W1895129514 hasConceptScore W1895129514C8891405 @default.
- W1895129514 hasIssue "3" @default.
- W1895129514 hasLocation W18951295141 @default.
- W1895129514 hasOpenAccess W1895129514 @default.
- W1895129514 hasPrimaryLocation W18951295141 @default.
- W1895129514 hasRelatedWork W1981870169 @default.
- W1895129514 hasRelatedWork W1991601972 @default.
- W1895129514 hasRelatedWork W203300858 @default.
- W1895129514 hasRelatedWork W2136175148 @default.
- W1895129514 hasRelatedWork W2141965224 @default.
- W1895129514 hasRelatedWork W2305870901 @default.
- W1895129514 hasRelatedWork W2402149178 @default.
- W1895129514 hasRelatedWork W2464086138 @default.
- W1895129514 hasRelatedWork W4251938332 @default.
- W1895129514 hasRelatedWork W74037808 @default.
- W1895129514 hasVolume "33" @default.
- W1895129514 isParatext "false" @default.
- W1895129514 isRetracted "false" @default.
- W1895129514 magId "1895129514" @default.
- W1895129514 workType "article" @default.