FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1895504297> ?p ?o ?g. }

• W1895504297 abstract "HomeCirculationVol. 106, No. 11Assessing Coronary Endothelial Dysfunction Free AccessLetterPDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessLetterPDF/EPUBAssessing Coronary Endothelial Dysfunction Calin V. Maniu, Stuart T. Higano and Amir Lerman Calin V. ManiuCalin V. Maniu Center for Coronary Physiology and Imaging, Mayo Clinic, Rochester, Minn Search for more papers by this author , Stuart T. HiganoStuart T. Higano Center for Coronary Physiology and Imaging, Mayo Clinic, Rochester, Minn Search for more papers by this author and Amir LermanAmir Lerman Center for Coronary Physiology and Imaging, Mayo Clinic, Rochester, Minn Search for more papers by this author Originally published10 Sep 2002https://doi.org/10.1161/01.CIR.0000030083.02775.D7Circulation. 2002;106:e48To the Editor:Hollenberg and colleagues report that coronary endothelial dysfunction, as detected by abnormal epicardial and microvascular responses to acetylcholine, preceded the development of clinical end points after heart transplantation.1 Similarly, we have shown that coronary endothelial dysfunction has an important effect on prognosis in patients with early coronary atherosclerosis. Although we acknowledge the importance of their findings and their potential clinical impact, we have some reservations about their study methods. The investigators appropriately assessed the microcirculation by measuring the coronary blood flow response to acetylcholine infusion with the use of the Doppler guidewire. The previously validated method for measuring coronary blood flow with the Doppler guidewire involves combining the averaged pulse-wave Doppler velocities with flow, or luminal, area at the site of the Doppler sample volume.2 Flow area is usually calculated from the angiographic diameter measured by use of quantitative coronary angiography methods. In this paper, the investigators measured flow area with intravascular ultrasound (IVUS) at a location “several centimeters” proximal to the Doppler sample volume. Other investigators have validated this method with the assumption that the lumen dimensions are constant along the vessel and that the Doppler measurements are made far enough downstream from the end of the IVUS catheter in which a parabolic velocity profile has reformed.3,4 In the current study, the investigators acknowledged that the wire was placed far distal to the IVUS catheter “to avoid flow artifact from catheter wake.” However, in allograft vasculopathy, one cannot assume that the lumen dimensions will be constant along the length of the vessel, especially during acetylcholine infusion. In patients with early coronary atherosclerosis, the acetylcholine response has been shown to be quite heterogeneous, with adjacent segments having discrepant constrictor and dilator responses.5 Therefore, the flow area at the IVUS catheter site may have been much different from the flow area at the Doppler sample volume. For measurement of absolute coronary blood flow during acetylcholine infusion, we advocate the generally accepted and validated method of combining flow area measured with the use of quantitative coronary angiography methods, rather than simultaneous IVUS and Doppler measurements.This study greatly adds to the understanding of allograft vasculopathy and we hope this understanding will translate into improved detection, treatment, and prevention of allograft vasculopathy in heart transplant patients.1 Hollenberg SM, Klein LW, Parrillo JE, et al. Coronary endothelial dysfunction after heart transplantation predicts allograft vasculopathy and cardiac death. Circulation. 2001; 104: 3091–6.CrossrefMedlineGoogle Scholar2 Doucette JW, Corl PD, Payne HM, et al. Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity. Circulation. 1992; 85: 1899–911.CrossrefMedlineGoogle Scholar3 Tadaoka S, Kagiyama M, Hiramatsu O, et al. Accuracy of 20-MHz Doppler catheter coronary artery velocimetry for measurement of coronary blood flow velocity. Cathet Cardiovasc Diagn. 1990; 19: 205–13.CrossrefMedlineGoogle Scholar4 Chou TM, Sudhir K, Iwanaga S, et al. Measurement of volumetric coronary blood flow by simultaneous intravascular two-dimensional and Doppler ultrasound: validation in an animal model. Am Heart J. 1994; 128: 237–43.CrossrefMedlineGoogle Scholar5 el-Tamimi H, Mansour M, Wargovich TJ, et al. Constrictor and dilator responses to intracoronary acetylcholine in adjacent segments of the same coronary artery in patients with coronary artery disease. Endothelial function revisited. Circulation. 1994; 89: 45–51.CrossrefMedlineGoogle ScholarcirculationahaCirculationCirculationCirculation0009-73221524-4539Lippincott Williams & WilkinsResponseHollenberg Steven M., , Parrillo Joseph E., , Scherer Markus, , Klein Lloyd W., , Burns Durand, , Tamburro Paul, , Oberoi Monica, Johnson Maryl R., , and Rosa Costanzo Maria, 10092002We appreciate the thoughtful comments of Drs Maniu, Higano, and Lerman. In our study, the Doppler flow wire was positioned several centimeters distal to the terminal portion of the IVUS catheter to avoid artifacts caused by the catheter wake.1 Thus, epicardial area and microvascular flow velocity responses were not obtained at the exact same point in the coronary tree, and this represents an acknowledged limitation of the study, for the reasons outlined in their letter. The methodology does, however, allow for simultaneous assessment of area and flow velocity, allowing for measurement of their time course and maximum response.2 Use of quantitative coronary angiography to measure coronary artery area at the site of the tip of the Doppler has its own limitations, including geometrical assumptions and resolution uncertainties secondary to cardiac motion,3 and although quantitative coronary angiography may be a more accurate method of measuring absolute coronary flow, it does not allow for assessment of the time course of the responses.Another factor that might mitigate this limitation in our study to some extent is the fact that we expressed our responses as a percentage of baseline for each patient, and thus the error introduced by the different positions would be the same (although heterogeneity in the acetylcholine response could occur, even over the short distance between the IVUS and the Doppler wire). We have analyzed the responses in our study with the use of flow velocity rather than calculated absolute flow, and the conclusions do not change. eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetailsCited By Ahmad A, Shelly-Cohen M, Corban M, Murphree Jr D, Toya T, Sara J, Ozcan I, Lerman L, Friedman P, Attia Z and Lerman A (2021) Machine learning aids clinical decision-making in patients presenting with angina and non-obstructive coronary artery disease, European Heart Journal - Digital Health, 10.1093/ehjdh/ztab084, 2:4, (597-605), Online publication date: 29-Dec-2022. Sara J, Prasad M, Zhang M, Lennon R, Herrmann J, Lerman L and Lerman A (2017) High-sensitivity C-reactive protein is an independent marker of abnormal coronary vasoreactivity in patients with non-obstructive coronary artery disease, American Heart Journal, 10.1016/j.ahj.2017.02.035, 190, (1-11), Online publication date: 1-Aug-2017. Prasad M, Matteson E, Herrmann J, Gulati R, Rihal C, Lerman L and Lerman A (2016) Uric Acid Is Associated With Inflammation, Coronary Microvascular Dysfunction, and Adverse Outcomes in Postmenopausal Women, Hypertension, 69:2, (236-242), Online publication date: 1-Feb-2017.Ahmad A, Corban M, Moriarty J, Kanaji Y, Rosedahl J, Gulati R, Rihal C, Prasad A, Sara J, Toya T, ter Horst I, Lerman L, Borah B and Lerman A Coronary Reactivity Assessment Is Associated With Lower Health Care–Associated Costs in Patients Presenting With Angina and Nonobstructive Coronary Artery Disease, Circulation: Cardiovascular Interventions, September 10, 2002Vol 106, Issue 11 Advertisement Article InformationMetrics https://doi.org/10.1161/01.CIR.0000030083.02775.D7PMID: 12221066 Originally publishedSeptember 10, 2002 PDF download Advertisement" @default.
• W1895504297 created "2016-06-24" @default.
• W1895504297 creator A5029129626 @default.
• W1895504297 creator A5073799750 @default.
• W1895504297 creator A5080490650 @default.
• W1895504297 date "2002-09-10" @default.
• W1895504297 modified "2023-09-23" @default.
• W1895504297 title "Assessing Coronary Endothelial Dysfunction" @default.
• W1895504297 cites W1974206361 @default.
• W1895504297 cites W2045402361 @default.
• W1895504297 cites W2089345006 @default.
• W1895504297 doi "https://doi.org/10.1161/01.cir.0000030083.02775.d7" @default.
• W1895504297 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12221066" @default.
• W1895504297 hasPublicationYear "2002" @default.
• W1895504297 type Work @default.
• W1895504297 sameAs 1895504297 @default.
• W1895504297 citedByCount "4" @default.
• W1895504297 countsByYear W18955042972017 @default.
• W1895504297 countsByYear W18955042972021 @default.
• W1895504297 countsByYear W18955042972023 @default.
• W1895504297 crossrefType "journal-article" @default.
• W1895504297 hasAuthorship W1895504297A5029129626 @default.
• W1895504297 hasAuthorship W1895504297A5073799750 @default.
• W1895504297 hasAuthorship W1895504297A5080490650 @default.
• W1895504297 hasBestOaLocation W18955042971 @default.
• W1895504297 hasConcept C126322002 @default.
• W1895504297 hasConcept C164705383 @default.
• W1895504297 hasConcept C2780972559 @default.
• W1895504297 hasConcept C71924100 @default.
• W1895504297 hasConceptScore W1895504297C126322002 @default.
• W1895504297 hasConceptScore W1895504297C164705383 @default.
• W1895504297 hasConceptScore W1895504297C2780972559 @default.
• W1895504297 hasConceptScore W1895504297C71924100 @default.
• W1895504297 hasIssue "11" @default.
• W1895504297 hasLocation W18955042971 @default.
• W1895504297 hasLocation W18955042972 @default.
• W1895504297 hasOpenAccess W1895504297 @default.
• W1895504297 hasPrimaryLocation W18955042971 @default.
• W1895504297 hasRelatedWork W2008851126 @default.
• W1895504297 hasRelatedWork W2011347913 @default.
• W1895504297 hasRelatedWork W2049397185 @default.
• W1895504297 hasRelatedWork W2073151595 @default.
• W1895504297 hasRelatedWork W2074833529 @default.
• W1895504297 hasRelatedWork W2125804349 @default.
• W1895504297 hasRelatedWork W2159512267 @default.
• W1895504297 hasRelatedWork W2304633692 @default.
• W1895504297 hasRelatedWork W2355498105 @default.
• W1895504297 hasRelatedWork W2399063111 @default.
• W1895504297 hasVolume "106" @default.
• W1895504297 isParatext "false" @default.
• W1895504297 isRetracted "false" @default.
• W1895504297 magId "1895504297" @default.
• W1895504297 workType "article" @default.