FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1895671324> ?p ?o ?g. }

• W1895671324 endingPage "3031" @default.
• W1895671324 startingPage "3024" @default.
• W1895671324 abstract "Children immunized with a formalin-inactivated respiratory syncytial virus (RSV) vaccine experienced enhanced disease and exhibited pulmonary eosinophilia upon natural RSV infection. BALB/c mice immunized with either formalin-inactivated RSV or a recombinant vaccinia virus (vacv) expressing the RSV attachment (G) protein develop extensive pulmonary eosinophilia after RSV challenge that mimics the eosinophilic response observed in the children during the 1960s vaccine trials. Fas ligand (FasL) is a major immune effector molecule that can contribute to the clearance of respiratory viruses. However, the role of FasL in the development of RSV vaccine-enhanced disease has not been elucidated. RSV challenge of vacvG-immunized gld mice, that lack functional FasL, results in diminished systemic disease as well as pulmonary eosinophilia. The magnitude of the secondary RSV G-specific CD4 T cell response was diminished in gld mice as compared with wild-type controls. Furthermore, we show that CD4 T cells isolated after RSV challenge of vacvG-immunized gld mice exhibit enhanced expression of Annexin V and caspase 3/7 indicating that FasL is important for either the survival or the expansion of virus-specific secondary effector CD4 T cells. Taken together, these data identify a previously undefined role for FasL in the accumulation of secondary effector CD4 T cells and the development of RSV vaccine-enhanced disease." @default.
• W1895671324 created "2016-06-24" @default.
• W1895671324 creator A5021945180 @default.
• W1895671324 creator A5081174860 @default.
• W1895671324 date "2009-03-01" @default.
• W1895671324 modified "2023-10-16" @default.
• W1895671324 title "Fas Ligand Is Required for the Development of Respiratory Syncytial Virus Vaccine-Enhanced Disease" @default.
• W1895671324 cites W1520674641 @default.
• W1895671324 cites W1544853784 @default.
• W1895671324 cites W1560119945 @default.
• W1895671324 cites W1616910822 @default.
• W1895671324 cites W1678614669 @default.
• W1895671324 cites W1749863242 @default.
• W1895671324 cites W1763037144 @default.
• W1895671324 cites W1894593978 @default.
• W1895671324 cites W1913350003 @default.
• W1895671324 cites W1925238017 @default.
• W1895671324 cites W1951599209 @default.
• W1895671324 cites W1972183604 @default.
• W1895671324 cites W1986331996 @default.
• W1895671324 cites W1991212304 @default.
• W1895671324 cites W1997491419 @default.
• W1895671324 cites W2002733542 @default.
• W1895671324 cites W2002767739 @default.
• W1895671324 cites W2004645606 @default.
• W1895671324 cites W2005653020 @default.
• W1895671324 cites W2006181104 @default.
• W1895671324 cites W2007939817 @default.
• W1895671324 cites W2008161823 @default.
• W1895671324 cites W2034249793 @default.
• W1895671324 cites W2034578152 @default.
• W1895671324 cites W2038915318 @default.
• W1895671324 cites W2042373141 @default.
• W1895671324 cites W2052300492 @default.
• W1895671324 cites W2063051740 @default.
• W1895671324 cites W2081749766 @default.
• W1895671324 cites W2086313080 @default.
• W1895671324 cites W2094211978 @default.
• W1895671324 cites W2094830672 @default.
• W1895671324 cites W2097531560 @default.
• W1895671324 cites W2104320636 @default.
• W1895671324 cites W2109503169 @default.
• W1895671324 cites W2113414525 @default.
• W1895671324 cites W2120750267 @default.
• W1895671324 cites W2120952482 @default.
• W1895671324 cites W2123817481 @default.
• W1895671324 cites W2125685304 @default.
• W1895671324 cites W2136277706 @default.
• W1895671324 cites W2137071409 @default.
• W1895671324 cites W2141538789 @default.
• W1895671324 cites W2141847513 @default.
• W1895671324 cites W2154567574 @default.
• W1895671324 cites W2155924232 @default.
• W1895671324 cites W2163813388 @default.
• W1895671324 cites W2171134740 @default.
• W1895671324 doi "https://doi.org/10.4049/jimmunol.0803585" @default.
• W1895671324 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2676854" @default.
• W1895671324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19234198" @default.
• W1895671324 hasPublicationYear "2009" @default.
• W1895671324 type Work @default.
• W1895671324 sameAs 1895671324 @default.
• W1895671324 citedByCount "5" @default.
• W1895671324 countsByYear W18956713242014 @default.
• W1895671324 countsByYear W18956713242015 @default.
• W1895671324 countsByYear W18956713242016 @default.
• W1895671324 crossrefType "journal-article" @default.
• W1895671324 hasAuthorship W1895671324A5021945180 @default.
• W1895671324 hasAuthorship W1895671324A5081174860 @default.
• W1895671324 hasBestOaLocation W18956713241 @default.
• W1895671324 hasConcept C159047783 @default.
• W1895671324 hasConcept C190283241 @default.
• W1895671324 hasConcept C203014093 @default.
• W1895671324 hasConcept C2522874641 @default.
• W1895671324 hasConcept C2776042228 @default.
• W1895671324 hasConcept C2777037409 @default.
• W1895671324 hasConcept C2777129736 @default.
• W1895671324 hasConcept C2780355102 @default.
• W1895671324 hasConcept C2780727368 @default.
• W1895671324 hasConcept C2780813555 @default.
• W1895671324 hasConcept C2781445406 @default.
• W1895671324 hasConcept C2909466502 @default.
• W1895671324 hasConcept C31573885 @default.
• W1895671324 hasConcept C51785407 @default.
• W1895671324 hasConcept C55493867 @default.
• W1895671324 hasConcept C66008609 @default.
• W1895671324 hasConcept C86803240 @default.
• W1895671324 hasConcept C8891405 @default.
• W1895671324 hasConceptScore W1895671324C159047783 @default.
• W1895671324 hasConceptScore W1895671324C190283241 @default.
• W1895671324 hasConceptScore W1895671324C203014093 @default.
• W1895671324 hasConceptScore W1895671324C2522874641 @default.
• W1895671324 hasConceptScore W1895671324C2776042228 @default.
• W1895671324 hasConceptScore W1895671324C2777037409 @default.
• W1895671324 hasConceptScore W1895671324C2777129736 @default.
• W1895671324 hasConceptScore W1895671324C2780355102 @default.
• W1895671324 hasConceptScore W1895671324C2780727368 @default.
• W1895671324 hasConceptScore W1895671324C2780813555 @default.
• W1895671324 hasConceptScore W1895671324C2781445406 @default.

• next