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- W1895698941 abstract "Summary. The mould collection of the Centraalbureau voor Schimmelcultures, Baarn, The Netherlands, was screened for isolates originating from warm‐blooded animals. The range of species indicates that distribution of clinically relevant, pathogenic or opportunistic strains over the fungal kingdom is non‐random. Some opportunistic fungi possess adaptations to life under hostile environmental conditions, enabling them to survive inside the human body. Presence of melanin or carotene seems to be an important virulence factor. Opportunistic fungi which sporulate in submersion are able to disseminate or cause severe local mycoses when the aspecific immune system of the host is impaired. Mycoses caused by a few dimorphic fungi, mostly in their natural ecological niche living in association with vertebrates, are promoted by specific immune deficiencies. Zusammenfassung. Die Pilzsammlung des Centraalbureau voor Schimmelcultures, Baarn, Niederlande, wurde auf Herkunft der Isolate untersucht. Die Verteilung klinisch relevanter Stämme über das Pilzreich ist nicht willkürlich. Opportunistische Pilze sind an extreme ökologi‐sche Bedingungen angepaßfit und können deswegen im menschlichen Körper überleben. Melanin und Carotin werden als wichtige Virulenz‐ Faktoren betrachtet. Einige opportunistische Pilze disseminieren oder verursachen ausgedehnte Läsionen, wenn das unspezifische Immunsystem geschädigt ist. Nur wenige, meistens dimorphe Pilze, welche in ihrer natürlichen ökologischen Nische an Wirbeltiere gebunden sind, werden erst infektiös bei geschwächter spezifischer Immu‐nabwehr des Wirtes." @default.
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- W1895698941 date "1992-09-01" @default.
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- W1895698941 title "The spectrum of opportunistic filamentous fungi present in the CBS culture collection" @default.
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- W1895698941 doi "https://doi.org/10.1111/j.1439-0507.1992.tb00849.x" @default.
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