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- W1895795536 abstract "Tax of human T-cell leukemia virus type 1 was analyzed for interaction with the cyclic AMP response element binding protein (CREB) in vitro with and without Tax response element DNA. Mutations in the carboxy terminus of Tax (L296G and L320G) did not affect binding to CREB and led to supershifts. In contrast, mutants with changes in the amino-terminal cysteine-rich region lost the ability to bind to CREB. The S10A mutant protein bound moderately. Thus, the amino terminus of Tax is essential for Tax-CREB interaction." @default.
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- W1895795536 date "1995-09-01" @default.
- W1895795536 modified "2023-09-25" @default.
- W1895795536 title "The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein" @default.
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- W1895795536 doi "https://doi.org/10.1128/jvi.69.9.5806-5811.1995" @default.
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